Skip to main content

AI-based AMD Analysis: A Review of Recent Progress

  • Conference paper
  • First Online:
Computer Vision – ACCV 2018 Workshops (ACCV 2018)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11367))

Included in the following conference series:

  • 1589 Accesses

Abstract

Since 2016 much progress has been made in the automatic analysis of age related macular degeneration (AMD). Much of it was dedicated to the classification of referable vs. non-referable AMD, fine-grained AMD severity classification, and assessing the five-year risk of progression to the severe form of AMD. Here we review these developments, the main tasks that were addressed, and the main methods that were carried out.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Although it was also suggested that this may not necessarily have a substantial influence on the generalizability of the deep learning models.

References

  1. Klein, R., Klein, B.E.K.: The prevalence of age-related eye diseases and visual impairment in aging: current estimates. Investig. Ophthalmol. Vis. Sci. 54(14) (2013)

    Article  Google Scholar 

  2. Velez-Montoya, R., Oliver, S.C.N., Olson, J.L., Fine, S.L., Quiroz-Mercado, H., Mandava, N.: Current knowledge and trends in age-related macular degeneration: genetics, epidemiology, and prevention. Retina 34(3), 423–441 (2014)

    Article  Google Scholar 

  3. Burlina, P., Freund, D.E., Dupas, B., Bressler, N.: Automatic screening of age-related macular degeneration and retinal abnormalities. In: 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC, pp. 3962–3966. IEEE (2011)

    Google Scholar 

  4. Holz, F.G., Strauss, E.C., Schmitz-Valckenberg, S., van Lookeren Campagne, M.: Geographic atrophy: clinical features and potential therapeutic approaches. Ophthalmology 121(5), 1079–1091 (2014)

    Article  Google Scholar 

  5. Venhuizen, F.G., et al.: Automated staging of age-related macular degeneration using optical coherence tomography. Investig. Ophthalmol. Vis. Sci. 58(4), 2318–2328 (2017)

    Article  Google Scholar 

  6. Freund, D.E., Bressler, N., Burlina, P.: Automated detection of drusen in the macula. In: 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, pp. 61–64. IEEE (2009)

    Google Scholar 

  7. Feeny, A.K., Tadarati, M., Freund, D.E., Bressler, N.M., Burlina, P.: Automated segmentation of geographic atrophy of the retinal epithelium via random forests in AREDS color fundus images. Comput. Biol. Med. 65, 124–136 (2015)

    Article  Google Scholar 

  8. Esteva, A., et al.: Dermatologist-level classification of skin cancer with deep neural networks. Nature 542(7639), 115–118 (2017)

    Article  Google Scholar 

  9. Burlina, P., Billings, S., Joshi, N., Albayda, J.: Automated diagnosis of myositis from muscle ultrasound: exploring the use of machine learning and deep learning methods. PloS one 12(8), e0184059 (2017)

    Article  Google Scholar 

  10. Burlina, P., Freund, D.E., Joshi, N., Wolfson, Y., Bressler, N.M.: Detection of age-related macular degeneration via deep learning. In: 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), pp. 184–188. IEEE (2016)

    Google Scholar 

  11. Burlina, P., Joshi, N., Pekala, M., Pacheco, K., Freund, D.E., Bressler, N.M.: Automated grading of age-related macular degeneration from color fundus images using deep convolutional neural networks. JAMA Ophtalmol. 135, 1170–1176 (2017)

    Article  Google Scholar 

  12. Burlina, P., Pacheco, K.D., Joshi, N., Freund, D.E., Bressler, N.M.: Comparing humans and deep learning performance for grading AMD: a study in using universal deep features and transfer learning for automated AMD analysis. Compu. Biol. Med. 82, 80–86 (2017)

    Article  Google Scholar 

  13. Burlina, P., Joshi, N., Pacheco, K.D., Freund, D.E., Kong, J., Bressler, N.M.: Use of deep learning for detailed severity characterization and estimation of 5-year risk among patients with age-related macular degeneration. JAMA Ophthalmol. 136, 1359–1366 (2018)

    Article  Google Scholar 

  14. Burlina, P., Joshi, N., Pacheco, K.D., Freund, D.E., Kong, J., Bressler, N.M.: Utility of deep learning methods for referability classification of age-related macular degeneration. JAMA Ophthalmol. 136, 1305–1307 (2018)

    Article  Google Scholar 

  15. Ting, D.S.W., et al.: Development and validation of a deep learning system for diabetic retinopathy and related eye diseases using retinal images from multiethnic populations with diabetes. JAMA 318(22), 2211–2223 (2017)

    Article  Google Scholar 

  16. Age-Related Eye Disease Study Research Group et al. The age-related eye disease study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the age-related eye disease study report number 6. Am. J. Ophthalmol. 132(5), 668–681 (2001)

    Google Scholar 

  17. Ting, D.S.W., Liu, Y., Burlina, P., Xu, X., Bressler, N.M., Wong, T.Y.: AI for medical imaging goes deep. Nat. Med. 24(5), 539 (2018)

    Article  Google Scholar 

  18. Grassmann, F., et al.: A deep learning algorithm for prediction of age-related eye disease study severity scale for age-related macular degeneration from color fundus photography. Ophthalmology 125, 1410–1420 (2018)

    Article  Google Scholar 

  19. Burlina, P.M., Joshi, N., Pacheco, K.D., Liu, T.Y.A., Bressler, N.M.: Assessment of deep generative models for high-resolution synthetic retinal image generation of age-related macular degeneration. JAMA Ophthalmol. 137(3), 258 (2019)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to P. Burlina .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Burlina, P., Joshi, N., Bressler, N.M. (2019). AI-based AMD Analysis: A Review of Recent Progress. In: Carneiro, G., You, S. (eds) Computer Vision – ACCV 2018 Workshops. ACCV 2018. Lecture Notes in Computer Science(), vol 11367. Springer, Cham. https://doi.org/10.1007/978-3-030-21074-8_25

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-21074-8_25

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21073-1

  • Online ISBN: 978-3-030-21074-8

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics