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Design, Optimization and Characterization of Bio-Hybrid Actuators Based on 3D-Bioprinted Skeletal Muscle Tissue

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Biomimetic and Biohybrid Systems (Living Machines 2019)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 11556))

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Abstract

The field of bio-hybrid robotics aims at the integration of biological components with artificial materials in order to take advantage of many unique features occurring in nature, such as adaptability, self-healing or resilience. In particular, skeletal muscle tissue has been used to fabricate bio-actuators or bio-robots that can perform simple actions. In this paper, we present 3D bioprinting as a versatile technique to develop these kinds of actuators and we focus on the importance of optimizing the designs and properly characterizing their performance. For that, we introduce a method to calculate the force generated by the bio-actuators based on the deflection of two posts included in the bio-actuator design by means of image processing algorithms. Finally, we present some results related to the adaptation, controllability and force modulation of our bio-actuators, paving the way towards a design- and optimization-driven development of more complex 3D-bioprinted bio-actuators.

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Author information

Authors and Affiliations

  1. Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 10-12, 08028, Barcelona, Spain

    Rafael Mestre, Tania Patiño, Maria Guix, Xavier Barceló & Samuel Sanchez

  2. Institució Catalana de Recerca i Estudis Avancats (ICREA), Barcelona, Spain

    Samuel Sanchez

Authors
  1. Rafael Mestre
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  2. Tania Patiño
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  3. Maria Guix
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  4. Xavier Barceló
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  5. Samuel Sanchez
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Corresponding author

Correspondence to Samuel Sanchez .

Editor information

Editors and Affiliations

  1. University of Bath, Bath, UK

    Uriel Martinez-Hernandez

  2. SPECS, Institute for Bioengineering of Catalonia, Barcelona, Spain

    Vasiliki Vouloutsi

  3. SPECS, Institute for Bioengineering of Catalonia, Barcelona, Spain

    Anna Mura

  4. University of Sheffield, Sheffield, UK

    Michael Mangan

  5. Osaka University, Suita, Japan

    Minoru Asada

  6. University of Sheffield, Sheffield, UK

    Tony J. Prescott

  7. SPECS, ICREA, BIST, Barcelona, Spain

    Paul F.M.J. Verschure

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Mestre, R., Patiño, T., Guix, M., Barceló, X., Sanchez, S. (2019). Design, Optimization and Characterization of Bio-Hybrid Actuators Based on 3D-Bioprinted Skeletal Muscle Tissue. In: Martinez-Hernandez, U., et al. Biomimetic and Biohybrid Systems. Living Machines 2019. Lecture Notes in Computer Science(), vol 11556. Springer, Cham. https://doi.org/10.1007/978-3-030-24741-6_18

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  • DOI: https://doi.org/10.1007/978-3-030-24741-6_18

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-24740-9

  • Online ISBN: 978-3-030-24741-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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