Abstract
Automatic nasopharyngeal carcinoma (NPC) segmentation in magnetic resonance (MR) images remains challenging since NPC is infiltrative and typically has a small or even tiny volume, making it indiscernible from tightly connected surrounding tissues. Recent methods using deep learning models performed unsatisfactorily since the boundary between NPC and its neighbor tissues is difficult to distinguish. In this paper, a novel Convolutional Neural Network (CNN) with recurrent attention modules (RAMs) is proposed to tackle the problem. To enhance the performance of NPC segmentation, the proposed fully automatic NPC segmentation method with recurrent attention exploits the semantic features in higher layers to guide the learning of features in lower layers. Features are fed into RAMs iteratively from the higher layers to the lower ones. The lower layers are updated iteratively by the guidance of higher layers to render with discriminative capability. Our proposed method was validated in a dataset including 596 patients, experimental results demonstrate that our method outperforms state-of-the-art methods.
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References
Wei, W.I., Sham, J.S.: Nasopharyngeal carcinoma. Lancet 365(9476), 2041–2054 (2005)
King, A.D., et al.: Neck node metastases from nasopharyngeal carcinoma: MR imaging of patterns of disease. J. Sci. Spec. Head Neck 22(3), 275–281 (2000)
Huang, K.W., Zhao, Z.Y., Gong, Q., Zha, J., Chen, L., Yang, R.: Nasopharyngeal carcinoma segmentation via HMRF-EM with maximum entropy. In: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 2968–2972. IEEE (2015)
Huang, W., Chan, K.L., Zhou, J.: Region-based nasopharyngeal carcinoma lesion segmentation from MRI using clustering- and classification-based methods with learning. J. Digit. Imaging 26(3), 472–482 (2013)
Zhou, J., Chan, K.L., Xu, P., Chong, V.F.: Nasopharyngeal carcinoma lesion segmentation from MR images by support vector machine. In: 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, pp. 1364–1367. IEEE (2006)
Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Men, K., et al.: Deep deconvolutional neural network for target segmentation of nasopharyngeal cancer in planning computed tomography images. Front. Oncol. 7, 315 (2017)
He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)
Russakovsky, O., et al.: Imagenet large scale visual recognition challenge. Int. J. Comput. Vision 115(3), 211–252 (2015)
Hu, J., Shen, L., Sun, G.: Squeeze-and-excitation networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7132–7141 (2018)
Jégou, S., Drozdzal, M., Vazquez, D., Romero, A., Bengio, Y.: The one hundred layers tiramisu: fully convolutional densenets for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition Workshops, pp. 11–19 (2017)
Acknowledgments
This work was supported by grants from the National Natural Science Foundation of China (no. 61771007, no. 81572652), Health & Medical Collaborative Innovation Project of Guangzhou City, China (grants 201604020003, 201803010021), Science and Technology Planning Projects of Guangdong Province (2016A010101013, 2017B020226004), and the Fundamental Research Fund for the Central Universities (2017ZD051).
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Huang, Jb., Zhuo, E., Li, H., Liu, L., Cai, H., Ou, Y. (2019). Achieving Accurate Segmentation of Nasopharyngeal Carcinoma in MR Images Through Recurrent Attention. In: Shen, D., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. MICCAI 2019. Lecture Notes in Computer Science(), vol 11768. Springer, Cham. https://doi.org/10.1007/978-3-030-32254-0_55
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DOI: https://doi.org/10.1007/978-3-030-32254-0_55
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