Abstract
Advances in high-throughput mapping of 3D genome organization have enabled genome-wide characterization of chromatin interactions. However, proximity ligation based mapping approaches for pairwise chromatin interaction such as Hi-C cannot capture multi-way interactions, which are informative to delineate higher-order genome organization and gene regulation mechanisms at single-nucleus resolution.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this paper
Cite this paper
Zhang, R., Ma, J. (2020). Probing Multi-way Chromatin Interaction with Hypergraph Representation Learning. In: Schwartz, R. (eds) Research in Computational Molecular Biology. RECOMB 2020. Lecture Notes in Computer Science(), vol 12074. Springer, Cham. https://doi.org/10.1007/978-3-030-45257-5_37
Download citation
DOI: https://doi.org/10.1007/978-3-030-45257-5_37
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-45256-8
Online ISBN: 978-3-030-45257-5
eBook Packages: Computer ScienceComputer Science (R0)