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Assessment and Comparison of Colour Fidelity of Whole Slide Imaging Scanners

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Artificial Intelligence and Machine Learning for Digital Pathology

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 12090))

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Abstract

The aim of this work is to develop a colourimetrically justified method for determination of colour fidelity of WSI scanners. We measure the absolute accuracy of colour reproduction and assess the scanner’s ability to resolve similar colours, which seems to be even more important for diagnostic and research tasks. Along this, some theoretical background is given which helps in understanding of common sources of failures in colour reproduction. The work was done in the framework of 2-nd and 3-rd International Scanner Contest. We hope this publication will be useful for scanner manufactures as well as for academical and clinical users.

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Notes

  1. 1.

     Sensors sensitive to reversible linear combination of cone spectral sensitivities, i.e. with channels as weighted sums of cone spectral responses, will work too.

  2. 2.

     The opposite case, i.e. low \(dE_{mean}\) and high \(dE_{var}\), is theoretically not possible because dE is always positive, thus, high \(dE_{var}\) will be accompanied with high \(dE_{mean}\) too.

  3. 3.

     As in 2012 and 2016, none of scanner manufacturers have provided colour profiles for their WSI scanners.

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Correspondence to Norman Zerbe .

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Zerbe, N., Alekseychuk, A., Hufnagl, P. (2020). Assessment and Comparison of Colour Fidelity of Whole Slide Imaging Scanners. In: Holzinger, A., Goebel, R., Mengel, M., Müller, H. (eds) Artificial Intelligence and Machine Learning for Digital Pathology. Lecture Notes in Computer Science(), vol 12090. Springer, Cham. https://doi.org/10.1007/978-3-030-50402-1_16

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  • DOI: https://doi.org/10.1007/978-3-030-50402-1_16

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  • Print ISBN: 978-3-030-50401-4

  • Online ISBN: 978-3-030-50402-1

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