Abstract
We consider a cell-based approach in which the balance of momentum is used to predict the impact of cellular forces on the surrounding tissue. To this extent, the elasticity equation and Dirac Delta distributions are combined. In order to avoid the singularity caused by Dirac Delta distribution, alternative approaches are developed and a Gaussian distribution is used as a smoothed approach. Based on the application that the pulling force is pointing inward the cell, the smoothed particle approach is probed as well. In one dimension, it turns out that the aforementioned three approaches are consistent. For two dimensions, we report a computational consistence between the direct and smoothed particle approach.
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Q. Peng and F. Vermolen, Point Forces and Their Alternatives in Cell-Based Models for Skin Contraction. Reports of the Delft Institute of Applied Mathematics, vol. 19-03, Delft University, the Netherlands, 2019. ISSN: 1389-6520
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The authors appreciate China Scholarship Council (CSC) for the financial support on this project.
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Peng, Q., Vermolen, F. (2021). Point Forces and Their Alternatives in Cell-Based Models for Skin Contraction. In: Vermolen, F.J., Vuik, C. (eds) Numerical Mathematics and Advanced Applications ENUMATH 2019. Lecture Notes in Computational Science and Engineering, vol 139. Springer, Cham. https://doi.org/10.1007/978-3-030-55874-1_75
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DOI: https://doi.org/10.1007/978-3-030-55874-1_75
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