Abstract
This paper uses network science techniques to evaluate the SATHCAP dataset concerning HIV and drug use. A referral network is generated via respondent-driven sampling, which is used to identify important bridge nodes that are responsible for maintaining the structure of large connected components of sexual and drug-using activity. These nodes are scrutinized to determine biomarkers and social factors that distinguish them from the underlying population. It is found that attributes such as homelessness and sexual abuse are more prevalent in these bridge nodes. These nodes are ill-served by public health efforts, because they are hard to reach and difficult to identify. Intervention campaigns targeted at groups displaying these attributes could meaningfully lower the spread of HIV.
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References
Albert, R., Jeong, H., Barabási, A.L.: Error and attack tolerance of complex networks. Nature 406(6794), 378–382 (2000)
Barabási, A.L., Bonabeau, E.: Scale-free networks. Sci. Am. 288(5), 60–69 (2003)
Bearman, P.S., Moody, J., Stovel, K.: Chains of affection: the structure of adolescent romantic and sexual networks. Am. J. Sociol. 110(1), 44–91 (2004)
Bell, D.C., Atkinson, J.S., Carlson, J.W.: Centrality measures for disease transmission networks. Soc. Netw. 21(1), 1–21 (1999)
Castilla, J., Del Romero, J., Hernando, V., Marincovich, B., GarcÃa, S., RodrÃguez, C.: Effectiveness of highly active antiretroviral therapy in reducing heterosexual transmission of HIV. JAIDS J. Acquired Immune Defic. Syndr. 40(1), 96–101 (2005)
Compton, W., Normand, J., Lambert, E.: Sexual acquisition and transmission of HIV cooperative agreement program (SATHCAP), July 2009. J. Urban Health 86(1), 1–4 (2009)
Crawford, F.W.: The graphical structure of respondent-driven sampling. Sociol. Methodol. 46(1), 187–211 (2016)
Deo, N.: Graph theory with application to engineering and computer science, pp. 39–44. phi pvt., Ltd., India (1974)
Eames, K.T.: Modelling disease spread through random and regular contacts in clustered populations. Theor. popul. Biol. 73(1), 104–111 (2008)
Freeman, L.C.: A set of measures of centrality based on betweenness. Sociometry 40, 35–41 (1977)
Gile, K.J., Handcock, M.S.: 7. respondent-driven sampling: an assessment of current methodology. Sociol. Methodol. 40(1), 285–327 (2010)
Goel, S., Salganik, M.J.: Assessing respondent-driven sampling. Proc. Nat. Acad. Sci. 107(15), 6743–6747 (2010)
Hagberg, A., Swart, P., SÂ Chult, D.: Exploring network structure, dynamics, and function using networkx. Technical Report, Los Alamos National Lab. (LANL), Los Alamos, NM (United States) (2008)
Holme, P., Kim, B.J., Yoon, C.N., Han, S.K.: Attack vulnerability of complex networks. Phys. Rev. 65(5), 056109 (2002)
Iguchi, M.Y., Ober, A.J., Berry, S.H., Fain, T., Heckathorn, D.D., Gorbach, P.M., Heimer, R., Kozlov, A., Ouellet, L.J., Shoptaw, S., et al.: Simultaneous recruitment of drug users and men who have sex with men in the united states and Russia using respondent-driven sampling: sampling methods and implications. J. Urban Health 86(1), 5 (2009)
Kuhns, L.M., Kwon, S., Ryan, D.T., Garofalo, R., Phillips, G., Mustanski, B.S.: Evaluation of respondent-driven sampling in a study of urban young men who have sex with men. J. Urban Health 92(1), 151–167 (2015)
Lee, S., Suzer-Gurtekin, T., Wagner, J., Valliant, R.: Total survey error and respondent driven sampling: focus on nonresponse and measurement errors in the recruitment process and the network size reports and implications for inferences. J. Official Stat. 33(2), 335–366 (2017)
Lloyd, A.L., May, R.M.: How viruses spread among computers and people. Science 292(5520), 1316–1317 (2001)
Lloyd-Smith, J.O., Schreiber, S.J., Kopp, P.E., Getz, W.M.: Superspreading and the effect of individual variation on disease emergence. Nature 438(7066), 355–359 (2005)
Magnani, R., Sabin, K., Saidel, T., Heckathorn, D.: Review of sampling hard-to-reach and hidden populations for HIV surveillance. Aids 19, S67–S72 (2005)
McKinney, W.: Data structures for statistical computing in python. In:  van der Walt, S., Millman, J. (eds.) Proceedings of the 9th Python in Science Conference, pp. 51 – 56 (2010)
Murphy, R.D., Gorbach, P.M., Weiss, R.E., Hucks-Ortiz, C., Shoptaw, S.J.: Seroadaptation in a sample of very poor Los Angeles area men who have sex with men. AIDS Behav. 17(5), 1862–1872 (2013)
Pellowski, J.A., Kalichman, S.C., Matthews, K.A., Adler, N.: A pandemic of the poor: social disadvantage and the us HIV epidemic. Am. Psychol. 68(4), 197 (2013)
Potterat, J.J., Phillips-Plummer, L., Muth, S.Q., Rothenberg, R., Woodhouse, D., Maldonado-Long, T., Zimmerman, H., Muth, J.: Risk network structure in the early epidemic phase of HIV transmission in Colorado springs. Sex. Transm. Infect. 78(suppl 1), i159–i163 (2002)
Rhodes, S.D., McCoy, T.P.: Condom use among immigrant Latino sexual minorities: multilevel analysis after respondent-driven sampling. AIDS Educ. Prev. 27(1), 27–43 (2015)
Wejnert, C.: 3. an empirical test of respondent-driven sampling: point estimates, variance, degree measures, and out-of-equilibrium data. Sociol. Methodol. 39(1), 73–116 (2009)
Youm, Y., Mackesy-Amiti, M.E., Williams, C.T., Ouellet, L.J.: Identifying hidden sexual bridging communities in Chicago. J. Urban Health 86(1), 107–120 (2009)
Young, S.D., Shoptaw, S., Weiss, R.E., Munjas, B., Gorbach, P.M.: Predictors of unrecognized HIV infection among poor and ethnic men who have sex with men in Los Angeles. AIDS Behav. 15(3), 643–649 (2011)
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Grubb, J., Lopez, D., Mohan, B., Matta, J. (2021). Identifying Biomarkers for Important Nodes in Networks of Sexual and Drug Activity. In: Benito, R.M., Cherifi, C., Cherifi, H., Moro, E., Rocha, L.M., Sales-Pardo, M. (eds) Complex Networks & Their Applications IX. COMPLEX NETWORKS 2020 2020. Studies in Computational Intelligence, vol 943. Springer, Cham. https://doi.org/10.1007/978-3-030-65347-7_30
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