Abstract
Studies have shown that the expansion of the lateral ventricle is closely related to many neurodegenerative diseases, so the segmentation of the lateral ventricle plays an important role in the diagnosis of related diseases. However, traditional segmentation methods are subjective, laborious, and time-consuming. Furthermore, due to the uneven magnetic field, irregular, small, and discontinuous shape of every single slice, the segmentation of the lateral ventricle is still a great challenge. In this paper, we propose an efficient and automatic lateral ventricle segmentation method in magnetic resonance (MR) images using a multi-scale feature fusion convolutional neural network (MFF-Net). First, we create a multi-center clinical dataset with a total of 117 patient MR scans. This dataset comes from two different hospitals and the images have different sampling intervals, different ages, and distinct image dimensions. Second, we present a new multi-scale feature fusion module (MSM) to capture different levels of feature information of lateral ventricles through various receptive fields. In particular, MSM can also extract the multi-scale lateral ventricle region feature information to solve the problem of insufficient feature extraction of small object regions with the deepening of network structure. Finally, extensive experiments have been conducted to evaluate the performance of the proposed MFF-Net. In addition, to verify the performance of the proposed method, we compare MFF-Net with seven state-of-the-art segmentation models. Both quantitative results and visual effects show that our MFF-Net outperforms other models and can achieve more accurate segmentation performance. The results also indicate that our model can be applied in clinical practice and is a feasible method for lateral ventricle segmentation.
F. Ye and Z. Wang—Co-first authors, contributed equally to this work.
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Acknowledgements
This work was supported by the National Natural Science Foundation of China under Grants 61802328, 61972333 and 61771415, the Natural Science Foundation of Hunan Province of China under Grant 2019JJ50606, and the Research Foundation of Education Department of Hunan Province of China under Grant 19B561.
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Ye, F., Wang, Z., Hu, K., Zhu, S., Gao, X. (2021). Automated Segmentation of Lateral Ventricle in MR Images Using Multi-scale Feature Fusion Convolutional Neural Network. In: Del Bimbo, A., et al. Pattern Recognition. ICPR International Workshops and Challenges. ICPR 2021. Lecture Notes in Computer Science(), vol 12666. Springer, Cham. https://doi.org/10.1007/978-3-030-68780-9_28
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