Abstract
When the world is rushing to test potential COVID-19 treatments, the limited resources and the overwhelming information demand the fast understanding of the promising drugs. This paper examines the multipurpose use of potential COVID-19 treatments by mining scientific papers on COVID-19 and related historical coronavirus research. Semantic shifts of the treatment-related entities are recognized to present their various applications in practice. The results identify 10 multipurpose entities. For selected entities, a detailed interpretation is given via text mining analysis about their possible use and rationale in different situations.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Mullard, A.: Flooded by the torrent: the COVID-19 drug pipeline. Lancet 395(10232), 1245–1246 (2020)
Wang, L. L., Lo, K., Chandrasekhar, Y., et al.: CORD-19: the Covid-19 open research dataset. ArXiv (2020)
Wei, C.H., Allot, A., Leaman, R., Lu, Z.: PubTator central: automated concept annotation for biomedical full text articles. Nucleic Acids Res. 47(W1), W587–W593 (2019)
Blei, D.M., Ng, A.Y., Jordan, M.I.: Latent dirichlet allocation. J. Mach. Learn. Res. 3, 993–1022 (2003)
Blei, D.M.: Probabilistic topic models. Commun. ACM 55(4), 77–84 (2012)
Rehurek, R., Sojka, P.: Software framework for topic modelling with large corpora. In: Proceedings of the LREC 2010 Workshop on New Challenges for NLP Frameworks, pp. 45–50 (2010)
Röder, M., Both, A., Hinneburg, A.: Exploring the space of topic coherence measures. In: Proceedings of the Eighth ACM International Conference on Web Search and Data Mining, WSDM 2015. pp. 399–408. Association for Computing Machinery, Shanghai (2015)
Wang, S., Schlobach, S., Klein, M.: Concept drift and how to identify it. Web Semant. Sci. Serv. Agents World Wide Web. 9(3), 247–265 (2011)
Hoffman, M., Bach, F.R., Blei, D.M.: online learning for latent dirichlet allocation. In: Advances in Neural Information Processing Systems, pp. 856–864 (2010)
Schneider, T.D.: Information Theory Primer with an Appendix on Logarithms. National Cancer Institute (2007)
Rossignol, J.F.: Nitazoxanide: a first-in-class broad-spectrum antiviral agent. Antiviral Res. 110, 94–103 (2014)
Xu, J., Shi, P.Y., Li, H., Zhou, J.: Broad spectrum antiviral agent niclosamide and its therapeutic potential. ACS Infect. Diseases 6(5), 909–915 (2020)
Acknowledgements
This research is supported by the MOE (Ministry of Education of China) Project of Humanities and Social Sciences [grant number 18YJC870002].
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this paper
Cite this paper
Chen, B., Yu, Q., Bu, Y., Ding, Y. (2021). Semantic Shifts Reveal the Multipurpose Use of Potential COVID-19 Treatments. In: Toeppe, K., Yan, H., Chu, S.K.W. (eds) Diversity, Divergence, Dialogue. iConference 2021. Lecture Notes in Computer Science(), vol 12645. Springer, Cham. https://doi.org/10.1007/978-3-030-71292-1_12
Download citation
DOI: https://doi.org/10.1007/978-3-030-71292-1_12
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-71291-4
Online ISBN: 978-3-030-71292-1
eBook Packages: Computer ScienceComputer Science (R0)