Abstract
The automated analysis of medical images requires robust and accurate algorithms that address the inherent challenges of identifying heterogeneous anatomical and pathological structures, such as brain tumors, in large volumetric images. In this paper, we present Cerberus, a single lightweight convolutional neural network model for the segmentation of fine-grained brain tumor regions in multichannel MRIs. Cerberus has an encoder-decoder architecture that takes advantage of a shared encoding phase to learn common representations for these regions and, then, uses specialized decoders to produce detailed segmentations. Cerberus learns to combine the weights learned for each category to produce a final multi-label segmentation. We evaluate our approach on the official test set of the Brain Tumor Segmentation Challenge 2020, and we obtain dice scores of 0.807 for enhancing tumor, 0.867 for whole tumor and 0.826 for tumor core.
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References
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Bakas, S., et al.: Segmentation labels and radiomic features for the pre-operative scans of the TCGA-LGG collection. Cancer Imaging Arch. 286 (2017)
Bakas, S., et al.: Segmentation labels and radiomic features for the pre-operative scans of the TCGA-GBM collection. Cancer Imaging Arch. Nat. Sci. Data 4, 170117 (2017)
Bakas, S., et al.: Advancing the cancer genome atlas glioma MRI collections with expert segmentation labels and radiomic features. Sci. Data 4, 170117 (2017)
Bakas, S., et al.: Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge. CoRR abs/1811.02629 (2018). http://arxiv.org/abs/1811.02629
Brügger, R., Baumgartner, C.F., Konukoglu, E.: A partially reversible u-net for memory-efficient volumetric image segmentation. CoRR abs/1906.06148 (2019). http://arxiv.org/abs/1906.06148
Chen, C., Liu, X., Ding, M., Zheng, J., Li, J.: 3D dilated multi-fiber network for real-time brain tumor segmentation in MRI. In: Shen, D., Liu, T., Peters, T.M., Staib, L.H., Essert, C., Zhou, S., Yap, P., Khan, A. (eds.) Medical Image Computing and Computer Assisted Intervention - MICCAI 2019–22nd International Conference, Shenzhen, China, 13–17 October 2019, Proceedings, Part III. Lecture Notes in Computer Science, vol. 11766, pp. 184–192. Springer (2019). https://doi.org/10.1007/978-3-030-32248-9_21
Chen, Y., Kalantidis, Y., Li, J., Yan, S., Feng, J.: Multi-fiber networks for video recognition. CoRR abs/1807.11195 (2018). http://arxiv.org/abs/1807.11195
Cheng, G., Cheng, J., Luo, M., He, L., Tian, Y., Wang, R.: Effective and efficient multitask learning for brain tumor segmentation. J. Real-Time Image Proc. 17(6), 1951–1960 (2020). https://doi.org/10.1007/s11554-020-00961-4
Gomez, A.N., Ren, M., Urtasun, R., Grosse, R.B.: The reversible residual network: Backpropagation without storing activations. CoRR abs/1707.04585 (2017). http://arxiv.org/abs/1707.04585
Imai, H., Matzek, S., Le, T.D., Negishi, Y., Kawachiya, K.: High resolution medical image segmentation using data-swapping method. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11766, pp. 238–246. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32248-9_27
Isensee, F., Kickingereder, P., Wick, W., Bendszus, M., Maier-Hein, K.H.: No new-net. In: Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, pp. 234–244 (2018). https://doi.org/10.1007/978-3-030-11726-9_21
Li, X., Luo, G., Wang, K.: Multi-step cascaded networks for brain tumor segmentation. CoRR abs/1908.05887 (2019). http://arxiv.org/abs/1908.05887
Menze, B.H., et al.: The multimodal brain tumor image segmentation benchmark (BRATS). IEEE Trans. Med. Imaging 34(10), 1993–2024 (2014)
Simpson, A.L., et al.: A large annotated medical image dataset for the development and evaluation of segmentation algorithms. CoRR abs/1902.09063 (2019). http://arxiv.org/abs/1902.09063
Wang, G., Li, W., Ourselin, S., Vercauteren, T.: Automatic brain tumor segmentation using cascaded anisotropic convolutional neural networks. In: Crimi, A., Bakas, S., Kuijf, H.J., Menze, B.H., Reyes, M. (eds.) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - Third International Workshop, BrainLes 2017, Held in Conjunction with MICCAI 2017, Quebec City, QC, Canada, 14 September 2017, Revised Selected Papers. Lecture Notes in Computer Science, vol. 10670, pp. 178–190. Springer (2017). https://doi.org/10.1007/978-3-319-75238-9_16
Wu, Y., He, K.: Group normalization. CoRR abs/1803.08494 (2018). http://arxiv.org/abs/1803.08494
Xu, H., Xie, H., Liu, Y., Cheng, C., Niu, C., Zhang, Y.: Deep cascaded attention network for multi-task brain tumor segmentation. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11766, pp. 420–428. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32248-9_47
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Daza, L., Gómez, C., Arbeláez, P. (2021). Cerberus: A Multi-headed Network for Brain Tumor Segmentation. In: Crimi, A., Bakas, S. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2020. Lecture Notes in Computer Science(), vol 12659. Springer, Cham. https://doi.org/10.1007/978-3-030-72087-2_30
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DOI: https://doi.org/10.1007/978-3-030-72087-2_30
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