Skip to main content

Multi-input Deep Convolutional Neural Network Based on Transfer Learning for Assisted Diagnosis of Alzheimer’s Disease

  • Conference paper
  • First Online:
HCI International 2021 - Posters (HCII 2021)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1420))

Included in the following conference series:

Abstract

Alzheimer’s Disease is the most common form of dementia which initially impairs the memory and finally progresses to death. There is no effective treatment for this irreversible disease. The latest innovations in multimodal neuroimaging data and artificial intelligence technology made it possible to detect this disease in the early stage, which has become a major research area in neuroscience. We proposed a deep learning algorithm using pre-train Restnet50 that takes both gray matter and white matter into account which would have a potential improvement to the existing CAD methods of AD diagnosis is utilized for the classification of brain images among Cognitively Normal (CN), Early Mild Cognitive Impairment (EMCL), Late Mild Cognitive Impairment (LMCI), Alzheimer’s Disease (AD), ensuring very precise and accurate diagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Alzheimer’s Association: 2017 Alzheimer’s disease facts and figures. Alzheimer’s Dementia, vol. 13, no. 4 (2017)

    Google Scholar 

  2. Jahn, H.: Memory loss in Alzheimer's disease. Dialogues Clin. Neurosci. 15(4), 445–54 (2013).https://doi.org/10.31887/DCNS.2013.15.4/hjahn

  3. LNCS Homepage. http://www.springer.com/lncs. Accessed 21 Nov 2016

  4. Sayeed, A., Petrou, M., Spyrou, N., Kadyrov, A., Spinks, T.: Diagnostic features of Alzheimer’s disease extracted from PET sinograms. Phys. Med. Biol. 47(1), 137–148 (2002)

    Article  Google Scholar 

  5. Desai, K.D., Parmar, P.S.: Effective early detection of Alzheimer’s and dementia disease using brain MRI scan images. Int. J. Emerg. Technol. Adv. Eng. 2(4), 414–417 (2012)

    Google Scholar 

  6. Duraisamy, B., Shanmugam, J.V., Annamalai, J.: Alzheimer disease detection from structural MR images using FCM based weighted probabilistic neural network. Brain Imaging Behav. 13(1), 87–110 (2018). https://doi.org/10.1007/s11682-018-9831-2

    Article  Google Scholar 

  7. Risacher, S.L., Saykin, A.J., Wes, J.D., Shen, L., Firpi, H.A., McDonald, B.C.: Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort. Curr. Alzheimer Res. 6(4), 347–361 (2009)

    Article  Google Scholar 

  8. Zhang, F., et al.: Semantic association for neuroimaging classification of PET images. J. Nuclear Med. 55(Suppl. 1), 2029–2029 (2014)

    Google Scholar 

  9. Khagi, B., Lee, C.G., Kwon, G.: Alzheimer’s disease classification from brain MRI based on transfer learning from CNN. In: 2018 11th Biomedical Engineering International Conference (BMEiCON), Chiang Mai, Thailand, pp. 1–4 (2018). https://doi.org/10.1109/BMEiCON.2018.8609974

  10. Simon, B.C., Baskar, D., Jayanthi, V.S.: Alzheimer’s disease classification using deep convolutional neural network. In: 2019 9th International Conference on Advances in Computing and Communication (ICACC), Kochi, India, pp. 204–208 (2019). https://doi.org/10.1109/ICACC48162.2019.8986170

  11. Liu, S., et al.: Multimodal neuroimaging feature learning for multiclass diagnosis of Alzheimer’s disease. IEEE Trans. Biomed. Eng. 62(4), 1132–1140 (2015)

    Article  Google Scholar 

  12. Kapoor, L., Thakur, S.: A survey on brain tumor detection using image processing techniques. In: 7th International Conference on Cloud Computing, Data Science & Engineering (2017)

    Google Scholar 

  13. Madusanka, N., Choi, H.K., So, J.H., et al.: Alzheimer’s disease classification based on multi-feature fusion. Curr. Med. Imaging Rev. 15(2), 161–169 (2018)

    Article  Google Scholar 

  14. Choi, B.K., et al.: Convolutional neural network-based MR image analysis for Alzheimer’s disease classification. Curr. Med Imaging Rev. 16(1), 27–35 (2020). https://doi.org/10.2174/1573405615666191021123854. PMID: 31989891

    Article  Google Scholar 

  15. Hosseini-Asl, E., Keynton, R., El-Baz, A.: Alzheimer’s disease diagnostics by adaptation of 3D convolutional network. In: 2016 IEEE International Conference on Image Processing (ICIP), pp. 126–130. IEEE (2016)

    Google Scholar 

  16. Goceri, E., Songul, C.: Biomedical information technology: image based computer aided diagnosis systems. In: International Conference on Advanced Technologies, Antalaya, Turkey (2018)

    Google Scholar 

  17. Gocer, E.: Diagnosis of Alzheimer’s disease with sobolev gradient based optimization and 3D convolutional neural network. J. Numer. Methods Biomed. Eng. 35(7), e3225 (2019)

    Google Scholar 

  18. Goceri, E.: Fully automated classification of brain tumors using capsules for Alzheimer’s disease diagnosis. IET Image Process (2019)

    Google Scholar 

  19. Goceri, E., Songül, C.: Computer-based segmentation, change detection and quantification for lesions in multiple sclerosis 2017. In: International Conference on Computer Science and Engineering (UBMK) Antalya, Antalya, Turkey, 5–7 October 2017, pp. 177–182 (2017)

    Google Scholar 

  20. Kim, J.P., et al.: Machine learning based hierarchical classification of frontotemporal dementia and Alzheimer’s disease. Neuroimage Clin. 23, 101811 (2019)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zhao Liu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Ling, W., Qin, Z., Liu, Z., Zhu, P. (2021). Multi-input Deep Convolutional Neural Network Based on Transfer Learning for Assisted Diagnosis of Alzheimer’s Disease. In: Stephanidis, C., Antona, M., Ntoa, S. (eds) HCI International 2021 - Posters. HCII 2021. Communications in Computer and Information Science, vol 1420. Springer, Cham. https://doi.org/10.1007/978-3-030-78642-7_68

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-78642-7_68

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-78641-0

  • Online ISBN: 978-3-030-78642-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics