Skip to main content

Deep Efficient Neural Networks for Explainable COVID-19 Detection on CXR Images

  • Conference paper
  • First Online:
Advances and Trends in Artificial Intelligence. Artificial Intelligence Practices (IEA/AIE 2021)

Abstract

With the spread of COVID-19 pandemic worldwide, medical imaging modalities and deep learning can play an important role in the fight against this disease. Recent years have seen the impressive results obtained using deep neural networks in different fields. Radiology is among the medical fields that can benefit from this recent progress and improve disease’s diagnosis, monitoring and prognosis. In this work, we propose the use of a deep efficient neural network based on EfficientNet B7 to detect COVID-19 in Chest X-rays (CXR). The obtained results on a large dataset are promising and show the high performance of the proposed model, with in average an accuracy of 95%, an AUC of 95%, a specificity of 90% and a sensitivity of 97%. In addition, an explainability model was developed and shows the high performance and high generalization degree of the proposed model in detecting and highlighting the signs of the disease.

This work was supported by Atlantic Canada Opportunities Agency (ACOA), Regional Economic Growth through Innovation - Business Scale-Up and Productivity (Project 217148), Natural Sciences and Engineering Research Council of Canada (NSERC), Alliance Grants (ALLRP 552039-20), New Brunswick Innovation Foundation (NBIF), COVID-19 Research Fund (COV2020-042), and the Microsoft AI For Health program.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Apostolopoulos, I.D., Mpesiana, T.A.: COVID-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks. Phys. Eng. Sci. Med. 43(2), 635–640 (2020)

    Article  Google Scholar 

  2. BIMCV Valencia Region, Pertusa, A., de la Iglesia Vaya, M.: BIMCV-COVID19+ (2020). https://doi.org/10.17605/OSF.IO/NH7G8. https://osf.io/nh7g8/

  3. Chetoui, M., Abadarahmane, T., Akhloufi, M.A.: Deep learning for COVID-19 detection on chest x-ray and CT scan. In: 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE (2020, poster)

    Google Scholar 

  4. Chetoui, M., Akhloufi, M.A.: Deep retinal diseases detection and explainability using OCT images. In: Campilho, A., Karray, F., Wang, Z. (eds.) ICIAR 2020. LNCS, vol. 12132, pp. 358–366. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-50516-5_31

    Chapter  Google Scholar 

  5. Chetoui, M., Akhloufi, M.A.: Explainable diabetic retinopathy using efficientnet. In: 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), pp. 1966–1969. IEEE (2020)

    Google Scholar 

  6. Chollet, F., et al.: Keras (2015). https://keras.io

  7. Chung, A.C.S., Gee, J.C., Yushkevich, P.A., Bao, S.: Information processing in medical imaging. In: Information Processing in Medical Imaging (2019)

    Google Scholar 

  8. Cohen, J.P., Morrison, P., Dao, L., Roth, K., Duong, T.Q., Ghassemi, M.: COVID-19 image data collection: prospective predictions are the future. arXiv 2006.11988 (2020). https://github.com/ieee8023/covid-chestxray-dataset

  9. Domingues, I., Pereira, G., Martins, P., Duarte, H., Santos, J., Abreu, P.H.: Using deep learning techniques in medical imaging: a systematic review of applications on CT and pet. Artif. Intell. Rev. 53(6), 4093–4160 (2020)

    Article  Google Scholar 

  10. Fang, Y., et al.: Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology 200432 (2020)

    Google Scholar 

  11. Farooq, M., Hafeez, A.: COVID-ResNet: a deep learning framework for screening of COVID19 from radiographs. arXiv preprint arXiv:2003.14395 (2020)

  12. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  13. Hemdan, E.E.D., Shouman, M.A., Karar, M.E.: COVIDX-Net: a framework of deep learning classifiers to diagnose COVID-19 in x-ray images. arXiv preprint arXiv:2003.11055 (2020)

  14. Hu, J., Shen, L., Sun, G.: Squeeze-and-excitation networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7132–7141 (2018)

    Google Scholar 

  15. Huang, G., Liu, Z., Van Der Maaten, L., Weinberger, K.Q.: Densely connected convolutional networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4700–4708 (2017)

    Google Scholar 

  16. Huang, Y., et al.: GPipe: efficient training of giant neural networks using pipeline parallelism. In: Advances in Neural Information Processing Systems, pp. 103–112 (2019)

    Google Scholar 

  17. Kermany, D.S., et al.: Identifying medical diagnoses and treatable diseases by image-based deep learning. Cell 172(5), 1122–1131.e9 (2018). https://doi.org/10.1016/j.cell.2018.02.010

  18. Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980 (2014)

  19. Liang, T., et al.: Handbook of COVID-19 prevention and treatment. The First Affiliated Hospital, Zhejiang University School of Medicine. Compiled According to Clinical Experience, vol. 68 (2020)

    Google Scholar 

  20. Malhotra, A., et al.: Multi-task driven explainable diagnosis of COVID-19 using chest x-ray images. arXiv preprint arXiv:2008.03205 (2020)

  21. Minaee, S., Kafieh, R., Sonka, M., Yazdani, S., Soufi, G.J.: Deep-COVID: predicting COVID-19 from chest x-ray images using deep transfer learning. arXiv preprint arXiv:2004.09363 (2020)

  22. Montfort, H.: Hopital Montfort (2020). https://hopitalmontfort.com/

  23. NVIDIA: 2080 Ti. https://www.nvidia.com/en-us/geforce/graphics-cards/rtx-2080. Accessed Jan 2021

  24. NVIDIA: K80. https://www.nvidia.com/fr-fr/data-center/tesla-k80/. Accessed Jan 2021

  25. Pan, I., Cadrin-Chênevert, A., Cheng, P.M.: Tackling the radiological society of North America pneumonia detection challenge. Am. J. Roentgenol. 213(3), 568–574 (2019)

    Article  Google Scholar 

  26. Rahman, T.: COVID-19 radiography database (2020). https://www.kaggle.com/tawsifurrahman/covid19-radiography-database

  27. Ramachandran, P., Zoph, B., Le, Q.V.: Searching for activation functions. arXiv preprint arXiv:1710.05941 (2017)

  28. Sandler, M., Howard, A., Zhu, M., Zhmoginov, A., Chen, L.C.: Mobilenetv 2: inverted residuals and linear bottlenecks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4510–4520 (2018)

    Google Scholar 

  29. Sandler, M., Howard, A.G., Zhu, M., Zhmoginov, A., Chen, L.: Inverted residuals and linear bottlenecks: mobile networks for classification, detection and segmentation. CoRR abs/1801.04381 (2018). http://arxiv.org/abs/1801.04381

  30. Selvaraju, R.R., Cogswell, M., Das, A., Vedantam, R., Parikh, D., Batra, D.: Grad-cam: visual explanations from deep networks via gradient-based localization. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 618–626 (2017)

    Google Scholar 

  31. Sethy, P.K., Behera, S.K.: Detection of coronavirus disease (COVID-19) based on deep features. Preprints 2020030300, 2020 (2020)

    Google Scholar 

  32. Shi, F., et al.: Review of artificial intelligence techniques in imaging data acquisition, segmentation and diagnosis for COVID-19. IEEE Rev. Biomed. Eng. (2020)

    Google Scholar 

  33. Shih, G., et al.: Augmenting the national institutes of health chest radiograph dataset with expert annotations of possible pneumonia. Radiol. Artif. Intell. 1(1), e180041 (2019)

    Google Scholar 

  34. Simonyan, K., Zisserman, A.: Very deep convolutional networks for large-scale image recognition. arxiv 2014. arXiv preprint arXiv:1409.1556 1409 (2014)

  35. Tan, M., et al.: Mnasnet: platform-aware neural architecture search for mobile. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 2820–2828 (2019)

    Google Scholar 

  36. Tan, M., Le, Q.V.: Efficientnet: rethinking model scaling for convolutional neural networks. CoRR abs/1905.11946 (2019). http://arxiv.org/abs/1905.11946

  37. Wang, L., Lin, Z.Q., Wong, A.: COVID-Net: a tailored deep convolutional neural network design for detection of COVID-19 cases from chest x-ray images. Sci. Rep. 10(1), 1–12 (2020)

    Article  Google Scholar 

  38. Wehbe, R.M., et al.: DeepCOVID-XR: an artificial intelligence algorithm to detect COVID-19 on chest radiographs trained and tested on a large US clinical dataset. Radiology 203511 (2020)

    Google Scholar 

  39. WHO: Coronavirus disease 2020 (2020). https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports

  40. WHO: Statement on the second meeting of the international health regulations (2005) emergency committee regarding the outbreak of novel coronavirus (2019-ncov) (2020). https://www.who.int/

  41. WHO: WHO director-general’s opening remarks at the media briefing on COVID-19 (2020). https://www.who.int

Download references

Acknowledgments

The authors would like to acknowledge El Mostafa Bouattane and Joseph Abdulnour (Institut du Savoir Montfort, Hôpital Montfort) for their assistance with organizing and sharing Montfort anonymized CXR images.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Moulay A. Akhloufi .

Editor information

Editors and Affiliations

Ethics declarations

Disclosures

The authors declare no conflict of interest.

Ethical Conduct of Research

The research ethics board at Université de Moncton waived ethics approval since our study does not involve direct work with humans, but only with anonymized images as described in the dataset section.

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Chetoui, M., Akhloufi, M.A. (2021). Deep Efficient Neural Networks for Explainable COVID-19 Detection on CXR Images. In: Fujita, H., Selamat, A., Lin, J.CW., Ali, M. (eds) Advances and Trends in Artificial Intelligence. Artificial Intelligence Practices. IEA/AIE 2021. Lecture Notes in Computer Science(), vol 12798. Springer, Cham. https://doi.org/10.1007/978-3-030-79457-6_29

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-79457-6_29

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-79456-9

  • Online ISBN: 978-3-030-79457-6

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics