Skip to main content

VAN: Voting and Attention Based Network for Unsupervised Medical Image Registration

  • Conference paper
  • First Online:
PRICAI 2021: Trends in Artificial Intelligence (PRICAI 2021)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 13031))

Included in the following conference series:

  • 2211 Accesses

Abstract

In this paper, a novel unsupervised network for medical image registration called VAN (Voting and Attention based Network) is proposed, in which the final deformation field is determined by the voting process between multiple registration branches. To reduce model parameters, multiple registration branches share one encoder. Besides, the attention mechanism is introduced, which further improves the network accuracy. We also adopt the method of single training and multiple-registrations to deal with the problem of the large deformation field. The experimental results show that the registration effect of our proposed network outperforms the baselines VoxelMorph and Symmetric Normalization (SyN) on three brain MRI image datasets.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Avants, B.B., Epstein, C.L., Grossman, M., Gee, J.C.: Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain. Med. Image Anal. 12(1), 26–41 (2008)

    Article  Google Scholar 

  2. Balakrishnan, G., Zhao, A., Sabuncu, M.R., Guttag, J., Dalca, A.V.: VoxelMorph: a learning framework for deformable medical image registration. IEEE Trans. Med. Imaging 38(8), 1788–1800 (2019)

    Article  Google Scholar 

  3. Beg, M.F., Miller, M.I., Trouv’e, A., Younes, L.: Computing large deformation metric mappings via geodesic flows of diffeomorphisms. Int. J. Comput. Vision 61(2), 139–157 (2005)

    Article  Google Scholar 

  4. Fabian, I., et al.: nnU-Net: self-adapting framework for u-net-based medical image segmentation. arXiv preprint arXiv:1809.10486 (2018)

  5. Fan, J.F., Cao, X.H., Wang, Q.W., Yap, P.T., Shen, D.G.: Adversarial learning for mono- or multi-modal registration. Med. Image Anal. 58, 101545 (2019)

    Article  Google Scholar 

  6. Fan, J.F., Cao, X.H., Yap, P.T., Shen, D.G.: BIRNet: brain image registration using dual-supervised fully convolutional networks. Med. Image Anal. 54, 193–206 (2019)

    Article  Google Scholar 

  7. Goodfellow, I., et al.: Generative adversarial nets. In: Advances in Neural Information Processing Systems, vol. 27, pp. 2672–2680 (2014)

    Google Scholar 

  8. Jaderberg, M., Simonyan, K., Zisserman, A., Kavukcuoglu, K.: Spatial transformer networks. In: Advances in Neural Information Processing Systems, vol. 28, pp. 2017–2025 (2015)

    Google Scholar 

  9. Jenkinson, M., Smith, S.: A global optimisation method for robust affine registration of brain images. Med. Image Anal. 5(2), 143–156 (2001)

    Article  Google Scholar 

  10. Kim, B., Kim, D.H., Park, S.H., Kim, J., Lee, J.G., Ye, J.C.: CycleMorph: cycle consistent unsupervised deformable image registration. arXiv preprint arXiv:2008.05772 (2020)

  11. Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. In: International Conference on Learning Representations (2015)

    Google Scholar 

  12. Mok, T.C.W., Chung, A.C.S.: Fast symmetric diffeomorphic image registration with convolutional neural networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4644–4653 (2020)

    Google Scholar 

  13. Ronneberger, O., Fischer, P., Brox, T.: U-Net: Convolutional networks for biomedical image segmentation. In: Medical Image Computing and Computer-Assisted Intervention, pp. 234–241 (2015)

    Google Scholar 

  14. Shan, S.Y., Guo, X.Q., Yan, W., Chang, E.I., Fan, Y.B., Xu, Y.: Unsupervised end-to-end learning for deformable medical image registration. arXiv preprint arXiv:1711.08608 (2017)

  15. Sokooti, H., de Vos, B., Berendsen, F., Lelieveldt, B.P.F., Išgum, I., Staring, M.: Nonrigid image registration using multi-scale 3D convolutional neural networks. In: Medical Image Computing and Computer Assisted Intervention, pp. 232–239 (2017)

    Google Scholar 

  16. Vercauteren, T., Pennec, X., Perchant, A., Ayache, N.: Diffeomorphic demons: efficient nonparametric image registration. Neuroimage 45(1), S61–S72 (2009)

    Article  Google Scholar 

  17. de Vos, B.D., Berendsen, F.F., Viergever, M.A., Staring, M., Išgum, I.: End-to-end unsupervised deformable image registration with a convolutional neural network. In: Deep Learning in Medical Image Analysis and Multimodal Learning for Clinical Decision Support, pp. 204–212 (2017)

    Google Scholar 

  18. Woo, S., Park, J., Lee, J.Y., Kweon, I.S.: Cbam: convolutional block attention module. In: Proceedings of the European Conference on Computer Vision (2018)

    Google Scholar 

  19. Zhang, J.: Inverse-consistent deep networks for unsupervised deformable image registration. arXiv preprint arXiv:1809.03443 (2018)

  20. Zhang, X.Y., Jian, W.J., Chen, Y., Yang, S.: Deform-GAN: An unsupervised learning model for deformable registration. arXiv preprint arXiv:2002.11430 (2020)

  21. Zhao, S.Y., Dong, Y., Chang, E.I.C., Xu, Y.: Recursive cascaded networks for unsupervised medical image registration. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 10600–10610 (2019)

    Google Scholar 

Download references

Acknowledgment

This work was supported by Shanghai Science and Technology Innovation Action Plan (18441909000, 20511100200), Science and Technology Commission of Shanghai Municipality (14DZ2260800), and OSTF foundation. The authors would like to thank Prof. Meng Yao of East China Normal University for fruitful discussion.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chaomin Shen .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Zu, Z., Zhang, G., Peng, Y., Ye, Z., Shen, C. (2021). VAN: Voting and Attention Based Network for Unsupervised Medical Image Registration. In: Pham, D.N., Theeramunkong, T., Governatori, G., Liu, F. (eds) PRICAI 2021: Trends in Artificial Intelligence. PRICAI 2021. Lecture Notes in Computer Science(), vol 13031. Springer, Cham. https://doi.org/10.1007/978-3-030-89188-6_29

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-89188-6_29

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-89187-9

  • Online ISBN: 978-3-030-89188-6

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics