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Brightening Up Brain Injuries: Design, Synthesis and Characterization of a PET Diagnostic Agent for Neuronal Trauma

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ICT for Health, Accessibility and Wellbeing (IHAW 2021)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1538))

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Abstract

Concussions are an increasingly significant issue today, however, there is still no single standard, objective criterion for diagnosing them. An objective test with high sensitivity and specificity for concussions would provide a substantial advance in concussion diagnostics, which can help in the prognosis, treatment, and medical decision-making regarding the disorder. This research looks to fill the void in concussion diagnostic techniques by synthesizing a specifically designed, small molecule [18] F-radiotracer capable of binding to a biomarker of neuronal trauma, thus allowing for the imaging of its upregulation using a PET scanner.

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Authors and Affiliations

  1. Lakehead University, Thunder Bay, ON, P7B 5E1, Canada

    Jessica Allingham, Wely B. Floriano & Michael Campbell

  2. Thunder Bay Regional Health Research Institute, Thunder Bay, ON, P7B 6V4, Canada

    Michael Campbell

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  1. Jessica Allingham
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  2. Wely B. Floriano
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  3. Michael Campbell
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Correspondence to Jessica Allingham .

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Editors and Affiliations

  1. Université de Rouen-Normandie, Rouen, France

    Edwige Pissaloux

  2. University of Cyprus, Nicosia, Cyprus

    George Angelos Papadopoulos

  3. Frederick University, Nicosia, Cyprus

    Achilleas Achilleos

  4. Universidad Panamericana, Aguascalientes, Mexico

    Ramiro Velázquez

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Allingham, J., Floriano, W.B., Campbell, M. (2021). Brightening Up Brain Injuries: Design, Synthesis and Characterization of a PET Diagnostic Agent for Neuronal Trauma. In: Pissaloux, E., Papadopoulos, G.A., Achilleos, A., Velázquez, R. (eds) ICT for Health, Accessibility and Wellbeing. IHAW 2021. Communications in Computer and Information Science, vol 1538. Springer, Cham. https://doi.org/10.1007/978-3-030-94209-0_8

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  • DOI: https://doi.org/10.1007/978-3-030-94209-0_8

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