Abstract
Knowledge graphs (KGs) are a way to model data involving intricate relations between a number of entities. Understanding the information contained in KGs and predicting what hidden relations may be present can provide valuable domain-specific knowledge. Thus, we use data provided by the 5th Annual Oak Ridge National Laboratory Smoky Mountains Computational Sciences Data Challenge 2 as well as auxiliary textual data processed with natural language processing techniques to form and analyze a COVID-19 KG of biomedical concepts and research papers. Moreover, we propose a recurrent graph convolutional network model that predicts both the existence of novel links between concepts in this COVID-19 KG and the time at which the link will form. We demonstrate our model’s promising performance against several baseline models. The utilization of our work can give insights that are useful in COVID-19-related fields such as drug development and public health. All code for our paper is publicly available at https://github.com/RemingtonKim/SMCDC2021.
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References
Caruana, R.: Multitask learning: a knowledge-based source of inductive bias. In: Proceedings of the Tenth International Conference on Machine Learning, pp. 41–48. Morgan Kaufmann (1993)
Defferrard, M., Bresson, X., Vandergheynst, P.: Convolutional neural networks on graphs with fast localized spectral filtering (2017)
Divakaran, A., Mohan, A.: Temporal link prediction: a survey. N. Gener. Comput. 38(1), 213–258 (2019)
Domingo-Fernández, D., et al.: COVID-19 knowledge graph: a computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology. Bioinformatics 37(9), 1332–1334 (2020)
Giarelis, N., Kanakaris, N., Karacapilidis, N.: On the utilization of structural and textual information of a scientific knowledge graph to discover future research collaborations: a link prediction perspective. In: Appice, A., Tsoumakas, G., Manolopoulos, Y., Matwin, S. (eds.) DS 2020. LNCS (LNAI), vol. 12323, pp. 437–450. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-61527-7_29
Grover, A., Leskovec, J.: node2vec: scalable feature learning for networks (2016)
Leskovec, J., Faloutsos, C.: Sampling from large graphs. In: KDD 2006, pp. 631–636. Association for Computing Machinery, New York (2006)
Li, J., Peng, J., Liu, S., Weng, L., Li, C.: TSAM: temporal link prediction in directed networks based on self-attention mechanism (2020)
Liben-Nowell, D., Kleinberg, J.: The link prediction problem for social networks. In: Proceedings of the Twelfth International Conference on Information and Knowledge Management, CIKM 2003, pp. 556–559. Association for Computing Machinery, New York (2003)
Mikolov, T., Chen, K., Corrado, G., Dean, J.: Efficient estimation of word representations in vector space (2013)
Peddada, A.V., Kostas, L.: Users and pins and boards, oh my! temporal link prediction over the Pinterest network (2016)
Ruder, S.: An overview of multi-task learning in deep neural networks (2017)
Seo, Y., Defferrard, M., Vandergheynst, P., Bresson, X.: Structured sequence modeling with graph convolutional recurrent networks. In: Cheng, L., Leung, A.C.S., Ozawa, S. (eds.) ICONIP 2018. LNCS, vol. 11301, pp. 362–373. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-04167-0_33
Wise, C., et al.: COVID-19 knowledge graph: accelerating information retrieval and discovery for scientific literature (2020)
Zhou, T., Lü, L., Zhang, Y.C.: Predicting missing links via local information. Eur. Phys. J. B 71(4), 623–630 (2009)
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Kim, R., Ning, Y. (2022). Recurrent Multi-task Graph Convolutional Networks for COVID-19 Knowledge Graph Link Prediction. In: Nichols, J., et al. Driving Scientific and Engineering Discoveries Through the Integration of Experiment, Big Data, and Modeling and Simulation. SMC 2021. Communications in Computer and Information Science, vol 1512. Springer, Cham. https://doi.org/10.1007/978-3-030-96498-6_24
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DOI: https://doi.org/10.1007/978-3-030-96498-6_24
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