Skip to main content

Multi-stage Domain Adaptation for Subretinal Fluid Classification in Cross-device OCT Images

  • Conference paper
  • First Online:
Pattern Recognition (ACPR 2021)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 13188))

Included in the following conference series:

  • 1029 Accesses

Abstract

Optical coherence tomography (OCT) is a practical basis that is widely used for computer-aided retinal diagnosis, and OCT images from different devices show obvious intensity distribution differences. Recently, deep learning based models have achieved promising results for the classification tasks on single-device OCT images. However, when the models trained on source domain images are transferred for the classification of the target domain images from another OCT device, we can observe significant performance degradation. Re-annotating target domain images and fine-tuning models are inefficient. In this paper, we propose a multi-stage domain adaptation method (MSDA), which can learn generalized and effective domain invariant information for cross-device OCT classification from labeled source domain images and unlabeled target domain images. Specifically, task-independent feature alignment (TiFA) module firstly maps OCT images with different distributions to the same latent space, where the original image information is effectively preserved. Then, the downstream task-specific feature alignment (TsFA) module further distills out category-associated features from the output of TiFA. The experimental results demonstrate that the proposed MSDA improves the subretinal fluid classification performance of cross-device OCT images.

This study was supported in part by National Natural Science Foundation of China (62172223, 61671242), in part by Key R & D Program of Jiangsu Science and Technology Department (BE2018131) and the Fundamental Research Funds for the Central Universities (30921013105).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ben-David, S., Blitzer, J., Crammer, K., Kulesza, A., Pereira, F., Vaughan, J.W.: A theory of learning from different domains. Mach. Learn. 79(1), 151–175 (2010)

    Article  MathSciNet  Google Scholar 

  2. Borgwardt, K.M., Gretton, A., Rasch, M.J., Kriegel, H.P., Schölkopf, B., Smola, A.J.: Integrating structured biological data by kernel maximum mean discrepancy. Bioinformatics 22(14), e49–e57 (2006)

    Article  Google Scholar 

  3. Duker, J.S., Waheed, N.K., Goldman, D.: Handbook of Retinal OCT: Optical Coherence Tomography E-Book. Elsevier, Amsterdam (2013)

    Google Scholar 

  4. Ghifary, M., Kleijn, W.B., Zhang, M.: Domain adaptive neural networks for object recognition. In: Pham, D.-N., Park, S.-B. (eds.) PRICAI 2014. LNCS (LNAI), vol. 8862, pp. 898–904. Springer, Cham (2014). https://doi.org/10.1007/978-3-319-13560-1_76

    Chapter  Google Scholar 

  5. Goodfellow, I.J., et al.: Generative adversarial networks. arXiv preprint arXiv:1406.2661 (2014)

  6. Hou, Y., Zheng, L.: Visualizing adapted knowledge in domain transfer. arXiv preprint arXiv:2104.10602 (2021)

  7. Jaffe, G.J., et al.: Macular morphology and visual acuity in the comparison of age-related macular degeneration treatments trials. Ophthalmology 120(9), 1860–1870 (2013)

    Article  Google Scholar 

  8. Johnson, M.W.: Etiology and treatment of macular edema. Am. J. Ophthalmol. 147(1), 11–21 (2009)

    Article  Google Scholar 

  9. Li, J., Chen, E., Ding, Z., Zhu, L., Lu, K., Shen, H.T.: Maximum density divergence for domain adaptation. IEEE Trans. Pattern Anal. Mach. Intell. 43, 3918–3930 (2020)

    Article  Google Scholar 

  10. Liu, M.Y., Breuel, T., Kautz, J.: Unsupervised image-to-image translation networks. arXiv preprint arXiv:1703.00848 (2017)

  11. Liu, M.Y., Tuzel, O.: Coupled generative adversarial networks. arXiv preprint arXiv:1606.07536 (2016)

  12. Long, M., Zhu, H., Wang, J., Jordan, M.I.: Unsupervised domain adaptation with residual transfer networks. arXiv preprint arXiv:1602.04433 (2016)

  13. Long, M., Zhu, H., Wang, J., Jordan, M.I.: Deep transfer learning with joint adaptation networks. In: International Conference on Machine Learning, pp. 2208–2217. PMLR (2017)

    Google Scholar 

  14. Oulbacha, R., Kadoury, S.: MRI to CT synthesis of the lumbar spine from a pseudo-3D cycle GAN. In: 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), pp. 1784–1787. IEEE (2020)

    Google Scholar 

  15. Romo-Bucheli, D., et al.: Reducing image variability across oct devices with unsupervised unpaired learning for improved segmentation of retina. Biomed. Opt. Express 11(1), 346–363 (2020)

    Article  Google Scholar 

  16. Saito, K., Watanabe, K., Ushiku, Y., Harada, T.: Maximum classifier discrepancy for unsupervised domain adaptation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3723–3732 (2018)

    Google Scholar 

  17. Schmidt-Erfurth, U., Klimscha, S., Waldstein, S., Bogunović, H.: A view of the current and future role of optical coherence tomography in the management of age-related macular degeneration. Eye 31(1), 26–44 (2017)

    Article  Google Scholar 

  18. Sun, B., Feng, J., Saenko, K.: Return of frustratingly easy domain adaptation. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 30 (2016)

    Google Scholar 

  19. Tzeng, E., Hoffman, J., Saenko, K., Darrell, T.: Adversarial discriminative domain adaptation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7167–7176 (2017)

    Google Scholar 

  20. Xie, X., Chen, J., Li, Y., Shen, L., Ma, K., Zheng, Y.: Self-supervised CycleGAN for object-preserving image-to-image domain adaptation. In: Vedaldi, A., Bischof, H., Brox, T., Frahm, J.-M. (eds.) ECCV 2020. LNCS, vol. 12365, pp. 498–513. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-58565-5_30

    Chapter  Google Scholar 

  21. Yu, F., Zhang, M., Dong, H., Hu, S., Dong, B., Zhang, L.: DAST: unsupervised domain adaptation in semantic segmentation based on discriminator attention and self-training. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 35, pp. 10754–10762 (2021)

    Google Scholar 

  22. Zhao, S., Li, B., Yue, X., Gu, Y., Xu, P., Hu, R., Chai, H., Keutzer, K.: Multi-source domain adaptation for semantic segmentation. arXiv preprint arXiv:1910.12181 (2019)

  23. Zhu, J.Y., Park, T., Isola, P., Efros, A.A.: Unpaired image-to-image translation using cycle-consistent adversarial networks. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 2223–2232 (2017)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Qiang Chen .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Li, T., Huang, K., Zhang, Y., Li, M., Zhang, W., Chen, Q. (2022). Multi-stage Domain Adaptation for Subretinal Fluid Classification in Cross-device OCT Images. In: Wallraven, C., Liu, Q., Nagahara, H. (eds) Pattern Recognition. ACPR 2021. Lecture Notes in Computer Science, vol 13188. Springer, Cham. https://doi.org/10.1007/978-3-031-02375-0_35

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-02375-0_35

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-02374-3

  • Online ISBN: 978-3-031-02375-0

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics