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EMSViT: Efficient Multi Scale Vision Transformer for Biomedical Image Segmentation

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Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (BrainLes 2021)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 12962))

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Abstract

In this paper, we propose a novel network named Efficient Multi Scale Vision Transformer for Biomedical Image Segmentation (EMSViT). Our network splits the input feature maps into three parts with \(1\times 1\), \(3\times 3\) and \(5\times 5\) convolutions in both encoder and decoder. Concat operator is used to merge the features before being fed to three consecutive transformer blocks with attention mechanism embedded inside it. Skip connections are used to connect encoder and decoder transformer blocks. Similarly, transformer blocks and multi scale architecture is used in decoder before being linearly projected to produce the output segmentation map. We test the performance of our network using Synapse multi-organ segmentation dataset, Automated cardiac diagnosis challenge dataset, Brain tumour MRI segmentation dataset and Spleen CT segmentation dataset. Without bells and whistles, our network outperforms most of the previous state of the art CNN and transformer based models using Dice score and the Hausdorff distance as the evaluation metrics.

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References

  • Bakas, S., et al.: Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the brats challenge. arXiv preprint arXiv:1811.02629 (2018)

  • Cao, H., et al.: Swin-UNet: UNet-like pure transformer for medical image segmentation. arXiv preprint arXiv:2105.05537 (2021)

  • Chen, J., et al.: TransUNet: transformers make strong encoders for medical image segmentation. arXiv preprint arXiv:2102.04306 (2021)

  • Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3D U-Net: learning dense volumetric segmentation from sparse annotation. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 424–432. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_49

    Chapter  Google Scholar 

  • Dosovitskiy, A., et al.: An image is worth 16x16 words: transformers for image recognition at scale. arXiv preprint arXiv:2010.11929 (2020)

  • Eelbode, T., et al.: Optimization for medical image segmentation: theory and practice when evaluating with dice score or Jaccard index. IEEE Trans. Med. Imaging 39(11), 3679–3690 (2020)

    Article  Google Scholar 

  • Fan, T., Wang, G., Li, Y., Wang, H.: MA-Net: a multi-scale attention network for liver and tumor segmentation. IEEE Access 8, 179656–179665 (2020)

    Article  Google Scholar 

  • Fu, S., et al.: Domain adaptive relational reasoning for 3D multi-organ segmentation. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12261, pp. 656–666. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59710-8_64

    Chapter  Google Scholar 

  • Gibson, E., et al.: Automatic multi-organ segmentation on abdominal CT with dense V-Networks. IEEE Trans. Med. Imaging 37(8), 1822–1834 (2018)

    Article  MathSciNet  Google Scholar 

  • Hatamizadeh, A., Yang, D., Roth, H., and Xu, D.: UNETR: transformers for 3D medical image segmentation. arXiv preprint arXiv:2103.10504 (2021)

  • Hu, H., Zhang, Z., Xie, Z., Lin, S.: Local relation networks for image recognition. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 3464–3473 (2019)

    Google Scholar 

  • Isensee, F., Jaeger, P.F., Kohl, S.A., Petersen, J., Maier-Hein, K.H.: nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat. Methods 18(2), 203–211 (2021)

    Article  Google Scholar 

  • Jin, Q., Meng, Z., Sun, C., Cui, H., Su, R.: RA-UNet: a hybrid deep attention-aware network to extract liver and tumor in CT scans. Front. Bioeng. Biotechnol. 8, 1471 (2020)

    Google Scholar 

  • Li, C., et al.: ANU-Net: attention-based nested U-Net to exploit full resolution features for medical image segmentation. Comput. Graph. 90, 11–20 (2020)

    Article  Google Scholar 

  • Li, X., Chen, H., Qi, X., Dou, Q., Fu, C.-W., Heng, P.-A.: H-DenseUNet: hybrid densely connected UNet for liver and tumor segmentation from CT volumes. IEEE Trans. Med. Imaging 37(12), 2663–2674 (2018)

    Article  Google Scholar 

  • Liu, L., Kurgan, L., Wu, F.-X., Wang, J.: Attention convolutional neural network for accurate segmentation and quantification of lesions in ischemic stroke disease. Med. Image Anal. 65, 101791 (2020)

    Article  Google Scholar 

  • Liu, Z., et al.: Swin transformer: hierarchical vision transformer using shifted windows. arXiv preprint arXiv:2103.14030 (2021)

  • Menze, B.H., et al.: The multimodal brain tumor image segmentation benchmark (BraTS). IEEE Trans. Med. Imaging 34(10), 1993–2024 (2014)

    Article  Google Scholar 

  • Myronenko, A.: 3D MRI brain tumor segmentation using autoencoder regularization. In: Crimi, A., Bakas, S., Kuijf, H., Keyvan, F., Reyes, M., van Walsum, T. (eds.) BrainLes 2018. LNCS, vol. 11384, pp. 311–320. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-11726-9_28

    Chapter  Google Scholar 

  • Ni, J., Wu, J., Tong, J., Chen, Z., Zhao, J.: GC-Net: global context network for medical image segmentation. Comput. Methods Program. Biomed. 190, 105121 (2020)

    Article  Google Scholar 

  • Oktay, O., et al.: Attention U-Net: learning where to look for the pancreas. arXiv preprint arXiv:1804.03999 (2018)

  • Parmar, N., et al.: Image transformer. In: International Conference on Machine Learning, pp. 4055–4064. PMLR (2018)

    Google Scholar 

  • Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  • Sagar, A.: Bayesian multi scale neural network for crowd counting. arXiv preprint arXiv:2007.14245 (2020)

  • Sagar, A.: Monocular depth estimation using multi scale neural network and feature fusion. arXiv preprint arXiv:2009.09934 (2020)

  • Sagar, A.: DMSANet: dual multi scale attention network. arXiv preprint arXiv:2106.08382 (2021)

  • Sagar, A., Soundrapandiyan, R.: Semantic segmentation with multi scale spatial attention for self driving cars. arXiv preprint arXiv:2007.12685 (2020)

  • Schlemper, J., et al.: Attention gated networks: learning to leverage salient regions in medical images. Med. Image Anal. 53, 197–207 (2019)

    Article  Google Scholar 

  • Simpson, A.L., et al.: A large annotated medical image dataset for the development and evaluation of segmentation algorithms. arXiv preprint arXiv:1902.09063 (2019)

  • Sinha, A., Dolz, J.: Multi-scale self-guided attention for medical image segmentation. IEEE J. Biomed. Health Inf. 25(1), 121-130 (2020)

    Google Scholar 

  • Touvron, H., Cord, M., Douze, M., Massa, F., Sablayrolles, A., Jégou, H.: Training data-efficient image transformers & distillation through attention. arXiv preprint arXiv:2012.12877 (2020)

  • Valanarasu, J.M.J., Oza, P., Hacihaliloglu, I., Patel, V.M.: Medical transformer: gated axial-attention for medical image segmentation. arXiv preprint arXiv:2102.10662 (2021)

  • Vaswani, A., et al.: Attention is all you need. arXiv preprint arXiv:1706.03762 (2017)

  • Wang, W., Chen, C., Ding, M., Li, J., Yu, H., Zha, S.: TransBTS: multimodal brain tumor segmentation using transformer. arXiv preprint arXiv:2103.04430 (2021)

  • Wang, X., Girshick, R., Gupta, A., He, K.: Non-local neural networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7794–7803 (2018)

    Google Scholar 

  • Xiao, X., Lian, S., Luo, Z., Li, S.: Weighted Res-UNet for high-quality retina vessel segmentation. In 2018 9th International Conference on Information Technology in Medicine and Education (ITME), pp. 327–331. IEEE (2018)

    Google Scholar 

  • Xie, Y., Zhang, J., Shen, C., Xia, Y.: CoTr: efficiently bridging CNN and transformer for 3D medical image segmentation. arXiv preprint arXiv:2103.03024 (2021)

  • Yu, L., et al.: Automatic 3D cardiovascular MR segmentation with densely-connected volumetric ConvNets. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10434, pp. 287–295. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66185-8_33

    Chapter  Google Scholar 

  • Zhang, Y., Liu, H., Hu, Q.: Transfuse: fusing transformers and CNNs for medical image segmentation. arXiv preprint arXiv:2102.08005 (2021)

  • Zhou, Z., Rahman Siddiquee, M.M., Tajbakhsh, N., Liang, J.: UNet++: a nested U-Net architecture for medical image segmentation. In: Stoyanov, D., et al. (eds.) DLMIA/ML-CDS -2018. LNCS, vol. 11045, pp. 3–11. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00889-5_1

    Chapter  Google Scholar 

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Correspondence to Abhinav Sagar .

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Sagar, A. (2022). EMSViT: Efficient Multi Scale Vision Transformer for Biomedical Image Segmentation. In: Crimi, A., Bakas, S. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2021. Lecture Notes in Computer Science, vol 12962. Springer, Cham. https://doi.org/10.1007/978-3-031-08999-2_3

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  • DOI: https://doi.org/10.1007/978-3-031-08999-2_3

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