Skip to main content

Brain Tumor Segmentation with Patch-Based 3D Attention UNet from Multi-parametric MRI

  • Conference paper
  • First Online:
Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (BrainLes 2021)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 12963))

Included in the following conference series:

Abstract

Accurate segmentation of different sub-regions of gliomas including peritumoral edema, necrotic core, enhancing and non-enhancing tumor core from multiparametric MRI scans has important clinical relevance in diagnosis, prognosis and treatment of brain tumors. However, due to the highly heterogeneous appearance and shape, segmentation of the sub-regions is very challenging. Recent development using deep learning models has proved its effectiveness in the past several brain segmentation challenges as well as other semantic and medical image segmentation problems. In this paper we developed a deep-learning-based segmentation method using a patch-based 3D UNet with the attention block. Hyper-parameters tuning and training and testing augmentations were applied to increase the model performance. Preliminary results showed effectiveness of the segmentation model and achieved mean Dice scores of 0.806 (ET), 0.863 (TC) and 0.918 (WT) in the validation dataset.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Kumar, V., et al.: Radiomics: the process and the challenges. Magn. Reson. Imaging 30, 1234–1248 (2012)

    Article  Google Scholar 

  2. Gillies, R.J., Kinahan, P.E., Hricak, H.: Radiomics: images are more than pictures. They Are Data Radiology 278, 563–577 (2015)

    Google Scholar 

  3. Baid, U., et al., The RSNA-ASNR-MICCAI BraTS 2021 benchmark on brain tumor segmentation and radiogenomic classification. arXiv:2107.02314 (2021)

  4. Menze, B.H., et al.: The multimodal brain tumor image segmentation benchmark (BRATS). IEEE Trans. Med. Imaging 34(10), 1993–2024 (2015). https://doi.org/10.1109/TMI.2014.2377694

    Article  Google Scholar 

  5. Bakas, S., et al.: Advancing the cancer genome atlas glioma MRI collections with expert segmentation labels and radiomic features. Nat. Sci. Data 4, 170117 (2017). https://doi.org/10.1038/sdata.2017.117

    Article  Google Scholar 

  6. Bakas, S., et al.: Segmentation labels and radiomic features for the pre-operative scans of the TCGA-GBM collection. The Cancer Imaging Archive (2017). https://doi.org/10.7937/K9/TCIA.2017.KLXWJJ1Q

    Article  Google Scholar 

  7. Bakas, S., et al.: Segmentation labels and radiomic features for the pre-operative scans of the TCGA-LGG collection. The Cancer Imaging Archive (2017). https://doi.org/10.7937/K9/TCIA.2017.GJQ7R0EF

    Article  Google Scholar 

  8. Bakas, S., et al.: Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge. arXiv preprint arXiv:1811.02629 (2018)

  9. Gal, Y., Ghahramani, Z.: Dropout as a bayesian approximation: representing model uncertainty in deep learning. arXiv preprint. arXiv:1506.02142 (2015)

  10. Pan, H., Feng, Y., Chen, Q., Meyer, C., Feng, X.: Prostate segmentation from 3D MRI using a two-stage model and variable-input based uncertainty measure. arXiv preprint. arXiv:1903.02500 (2019)

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xue Feng .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Feng, X., Bai, H., Kim, D., Maragkos, G., Machaj, J., Kellogg, R. (2022). Brain Tumor Segmentation with Patch-Based 3D Attention UNet from Multi-parametric MRI. In: Crimi, A., Bakas, S. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2021. Lecture Notes in Computer Science, vol 12963. Springer, Cham. https://doi.org/10.1007/978-3-031-09002-8_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-09002-8_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-09001-1

  • Online ISBN: 978-3-031-09002-8

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics