Abstract
Deep learning methods, especially convolutional neural networks, have become more and more popular in medical image classifications. However, training a deep neural network from scratch can be a luxury for many medical image datasets as the process requires a large and well-balanced sample to output satisfactory results. Unlike natural image datasets, medical images are expensive to collect owing to labor and equipment costs. Besides, the class labels in medical image datasets are usually severely imbalanced subject to the availability of patients. Further, aggregating medical images from multiple sources can be challenging due to policy restrictions, privacy concerns, communication costs, and data heterogeneity caused by equipment differences and labeling discrepancies. In this paper, we propose to address these issues with the help of transfer learning and artificial samples created by generative models. Instead of requesting medical images from source data, our method only needs a parsimonious supplement of model parameters pre-trained on the source data. The proposed method preserves the data privacy in the source data and significantly reduces the communication cost. Our study shows transfer learning together with artificial samples can improve the pneumonia classification accuracy on a small but heavily imbalanced chest X-ray image dataset by \(11.53\%\) which performs even better than directly augmenting that source data into the training process.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
Available at https://data.mendeley.com/datasets/rscbjbr9sj/2.
- 2.
Available at https://nihcc.app.box.com/v/ChestXray-NIHCC.
References
Albahli, S., Rauf, H.T., Arif, M., Nafis, M.T., Algosaibi, A.: Identification of thoracic diseases by exploiting deep neural networks. Neural Netw. 5, 6 (2021)
Arjovsky, M., Bottou, L.: Towards principled methods for training generative adversarial networks (2017)
Arjovsky, M., Chintala, S., Bottou, L.: Wasserstein GAN (2017)
Azizpour, H., Razavian, A.S., Sullivan, J., Maki, A., Carlsson, S.: Factors of transferability for a generic convnet representation. IEEE Trans. Pattern Anal. Mach. Intell. 38(9), 1790–1802 (2015)
Buda, M., Maki, A., Mazurowski, M.A.: A systematic study of the class imbalance problem in convolutional neural networks. Neural Netw. 106, 249–259 (2018)
Cai, T.T., Wei, H.: Transfer learning for nonparametric classification: minimax rate and adaptive classifier. Ann. Statist. 49(1), 100–128 (2021)
Chowdhury, N.I., Smith, T.L., Chandra, R.K., Turner, J.H.: Automated classification of osteomeatal complex inflammation on computed tomography using convolutional neural networks. In: International forum of Allergy & Rhinology, vol. 9, pp. 46–52. Wiley Online Library (2019)
Gao, J., Jiang, Q., Zhou, B., Chen, D.: Convolutional neural networks for computer-aided detection or diagnosis in medical image analysis: an overview. Math. Biosci. Eng. 16(6), 6536–6561 (2019)
Giger, M.L., Suzuki, K.: Computer-aided diagnosis. In: Biomedical Information Technology, pp. 359-XXII. Elsevier (2008)
Goodfellow, I.J., et al.: Generative adversarial networks (2014)
Gulrajani, I., Ahmed, F., Arjovsky, M., Dumoulin, V., Courville, A.: Improved training of Wasserstein GANs (2017)
Halalli, B., Makandar, A.: Computer aided diagnosis-medical image analysis techniques. In: Breast Imaging, p. 85 (2018)
Hinton, G.E., Salakhutdinov, R.R.: Reducing the dimensionality of data with neural networks. Science 313(5786), 504–507 (2006)
Hosny, K.M., Kassem, M.A., Foaud, M.M.: Classification of skin lesions using transfer learning and augmentation with Alex-net. PLOS ONE 14(5), e0217293 (2019)
Ioffe, S., Szegedy, C.: Batch normalization: accelerating deep network training by reducing internal covariate shift (2015)
Kermany, D.S., Zhang, K., Goldbaum, M.H.: Labeled optical coherence tomography (OCT) and chest x-ray images for classification (2018)
Kingma, D.P., Ba, J.: Adam: A method for stochastic optimization (2017)
Kingma, D.P., Welling, M.: Auto-encoding variational bayes (2014)
Krizhevsky, A., Sutskever, I., Hinton, G.E.: ImageNet classification with deep convolutional neural networks. In: Advances in Neural Information Processing Systems, pp. 1097–1105 (2012)
Krizhevsky, A., Sutskever, I., Hinton, G.E.: ImageNet classification with deep convolutional neural networks. In: Pereira, F., Burges, C.J.C., Bottou, L., Weinberger, K.Q. (eds.) Advances in Neural Information Processing Systems. Curran Associates, Inc. (2012)
Lawrence, S., Giles, C.L., Tsoi, A.C., Back, A.D.: Face recognition: a convolutional neural-network approach. IEEE Trans. Neural Netw. 8(1), 98–113 (1997)
Lee, K.S., Jung, S.K., Ryu, J.J., Shin, S.W., Choi, J.: Evaluation of transfer learning with deep convolutional neural networks for screening osteoporosis in dental panoramic radiographs. J. Clin. Med. 9(2), 392 (2020)
Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)
Long, M., Cao, Y., Wang, J., Jordan, M.: Learning transferable features with deep adaptation networks. In: Proceedings of the 32nd International Conference on International Conference on Machine Learning (ICML), vol. 13, pp. 97–105 (2015)
Long, M., Zhu, H., Wang, J., Jordan, M.I.: Unsupervised domain adaptation with residual transfer networks. In: Advances in Neural Information Processing Systems, pp. 136–144 (2016)
Lu, D., Weng, Q.: A survey of image classification methods and techniques for improving classification performance. Int. J. Remote Sens. 28(5), 823–870 (2007)
Maas, A.L., Hannun, A.Y., Ng, A.Y.: Rectifier nonlinearities improve neural network acoustic models. In: ICML Workshop on Deep Learning for Audio, Speech and Language Processing (2013)
Mahendran, A., Vedaldi, A.: Understanding deep image representations by inverting them. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 5188–5196 (2015)
Maity, S., Sun, Y., Banerjee, M.: Minimax optimal approaches to the label shift problem. arXiv preprint arXiv:2003.10443 (2020)
Maninis, K.-K., Pont-Tuset, J., Arbeláez, P., Van Gool, L.: Deep retinal image understanding. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 140–148. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_17
Mao, J., Jain, A.K.: Artificial neural networks for feature extraction and multivariate data projection. IEEE Trans. Neural Netw. 6(2), 296–317 (1995)
Mirza, M., Osindero, S.: Conditional generative adversarial nets (2014)
Mou, L., et al.: How transferable are neural networks in NLP applications? arXiv preprint arXiv:1603.06111 (2016)
Qin, X., Bui, F.M., Nguyen, H.H.: Learning from an imbalanced and limited dataset and an application to medical imaging. In: 2019 IEEE Pacific Rim Conference on Communications, Computers and Signal Processing (PACRIM), pp. 1–6. IEEE (2019)
Radford, A., Metz, L., Chintala, S.: Unsupervised representation learning with deep convolutional generative adversarial networks (2016)
Rocher, L., Hendrickx, J.M., De Montjoye, Y.A.: Estimating the success of re-identifications in incomplete datasets using generative models. Nat. Commun. 10(1), 1–9 (2019)
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Russakovsky, O., et al.: ImageNet large scale visual recognition challenge. Int. J. Comput. Vision 115(3), 211–252 (2015). https://doi.org/10.1007/s11263-015-0816-y
Sharma, H., Jain, J.S., Bansal, P., Gupta, S.: Feature extraction and classification of chest x-ray images using CNN to detect pneumonia. In: 2020 10th International Conference on Cloud Computing, Data Science & Engineering (Confluence), pp. 227–231. IEEE (2020)
Simonyan, K., Zisserman, A.: Very deep convolutional networks for large-scale image recognition (2015)
Stephen, O., Sain, M., Maduh, U.J., Jeong, D.U.: An efficient deep learning approach to pneumonia classification in healthcare. J. Healthcare Eng. 2019 (2019)
Stoitsis, J., et al.: Computer aided diagnosis based on medical image processing and artificial intelligence methods. Nuclear Instrum. Methods Phys. Res. Sect. A: Accel. Spectrom. Detect. Assoc. Equip. 569(2), 591–595 (2006)
Tian, Y., Feng, Y.: Transfer learning under high-dimensional generalized linear models. arXiv preprint arXiv:2105.14328 (2021)
Wang, X., Peng, Y., Lu, L., Lu, Z., Bagheri, M., Summers, R.M.: ChestX-ray8: Hospital-scale chest x-ray database and benchmarks on weakly-supervised classification and localization of common thorax diseases. In: 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), July 2017
White, T., Blok, E., Calhoun, V.D.: Data sharing and privacy issues in neuroimaging research: opportunities, obstacles, challenges, and monsters under the bed. Human Brain Map. 43(1), 278–291 (2022)
Yosinski, J., Clune, J., Bengio, Y., Lipson, H.: How transferable are features in deep neural networks? In: Advances in neural information processing systems (NIPS), pp. 3320–3328 (2014)
Zhang, C., et al.: A visual encoding model based on deep neural networks and transfer learning for brain activity measured by functional magnetic resonance imaging. J. Neurosci. Methods 325, 108318 (2019)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this paper
Cite this paper
Li, X., Ke, Y. (2022). Privacy Preserving and Communication Efficient Information Enhancement for Imbalanced Medical Image Classification. In: Yang, G., Aviles-Rivero, A., Roberts, M., Schönlieb, CB. (eds) Medical Image Understanding and Analysis. MIUA 2022. Lecture Notes in Computer Science, vol 13413. Springer, Cham. https://doi.org/10.1007/978-3-031-12053-4_49
Download citation
DOI: https://doi.org/10.1007/978-3-031-12053-4_49
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-12052-7
Online ISBN: 978-3-031-12053-4
eBook Packages: Computer ScienceComputer Science (R0)