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A Coarse-to-Fine Network for Craniopharyngioma Segmentation

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Machine Learning in Medical Imaging (MLMI 2022)

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Abstract

Craniopharyngioma (CP) is one of the most common intracranial tumors located in the sellar region and its surroundings, which often leads to visual acuity, visual field disorders, and pituitary hypothalamus dysfunction. Segmentation of CP is an essential prerequisite in the diagnosis, screening, and treatment. Also, It’s a challenging task due to the indistinguishable borders, the small tumor size, and high diversity in size, shape, and texture. In this work, a novel automatic coarse-to-fine CP segmentation network is proposed, consisting of two stages: the coarse segmentation stage and the refinement stage. During the first stage, the Coarse Segmentation Guided Module (CSGM) is proposed to generate rough segmentation results and exclude the interference of background regions. During the refinement stage, the Local Feature Aggregation (LFA) module is proposed to solve the boundary ambiguity problem. It can encode the fine-grained information and adaptively explore the dependencies between a local spatial neighborhood. To validate the effectiveness of our model, a realistic CP dataset was constructed and a 4.26% dice score promotion is achieved compared to the baseline.

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References

  1. Müller, H.L.: Childhood craniopharyngioma. Pituitary 16(1), 56–67 (2013)

    Article  Google Scholar 

  2. Stamm, A.C., Vellutini, E., Balsalobre, L.: Craniopharyngioma. Otolaryngol. Clin. North Am. 44(4), 937–952 (2011)

    Article  Google Scholar 

  3. Müller, H.L., Merchant, T.E., Warmuth-Metz, M., Martinez-Barbera, J.P., Puget, S.: Craniopharyngioma. Nature Rev. Disease Primers 5(1), 1–19 (2019)

    Article  Google Scholar 

  4. Inenaga, C., Kakita, A., Iwasaki, Y., Yamatani, K., Takahashi, H.: Autopsy findings of a craniopharyngioma with a natural course over 60 years. Surg. Neurol. 61(6), 536–540 (2004)

    Article  Google Scholar 

  5. Iandola, F.N., Han, S., Moskewicz, M.W., Ashraf, K., Dally, W.J., Keutzer, K.: SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and< 0.5 MB model size. arXiv preprint arXiv:1602.07360 (2016)

  6. Fan, D., et al.: Inf-Net: automatic COVID-19 lung infection segmentation from CT images. IEEE Trans. Med. Imaging 39(8), 2626–2637 (2020)

    Article  Google Scholar 

  7. Takikawa, T., Acuna, D., Jampani, V., Fidler, S.: Gated-SCNN: gated shape CNNs for semantic segmentation. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 5229–5238 (2019)

    Google Scholar 

  8. Oktay, O., et al.: Attention U-Net: learning where to look for the pancreas. arXiv preprint arXiv:1804.03999 (2018)

  9. Zhang, Z., Fu, H., Dai, H., Shen, J., Pang, Y., Shao, L.: ET-Net: a generic Edge-aTtention guidance network for medical image segmentation. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11764, pp. 442–450. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32239-7_49

    Chapter  Google Scholar 

  10. Feng, S., et al.: CPFNet: context pyramid fusion network for medical image segmentation. IEEE Trans. Med. Imaging 39(10), 3008–3018 (2020)

    Article  Google Scholar 

  11. Kaluva, K.C., Khened, M., Kori, A., Krishnamurthi, G.: 2D-densely connected convolution neural networks for automatic liver and tumor segmentation. arXiv preprint arXiv:1802.02182 (2018)

  12. Feng, X., Wang, C., Cheng, S., Guo, L.: Automatic liver and tumor segmentation of CT based on cascaded U-Net. In: Jia, Y., Du, J., Zhang, W. (eds.) Proceedings of 2018 Chinese Intelligent Systems Conference. LNEE, vol. 529, pp. 155–164. Springer, Singapore (2019). https://doi.org/10.1007/978-981-13-2291-4_16

    Chapter  Google Scholar 

  13. Albishri, A.A., Shah, S.J.H., Lee, Y.: CU-Net: cascaded u-net model for automated liver and lesion segmentation and summarization. In: 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), pp. 1416–1423. IEEE (2019)

    Google Scholar 

  14. Yan, Y., et al.: Cascaded multi-scale convolutional encoder-decoders for breast mass segmentation in high-resolution mammograms. In: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 6738–6741. IEEE (2019)

    Google Scholar 

  15. Ma, Q., Zu, C., Wu, X., Zhou, J., Wang, Y.: Coarse-to-fine segmentation of organs at risk in nasopharyngeal carcinoma radiotherapy. In: de Bruijne, M., et al. (eds.) MICCAI 2021. LNCS, vol. 12901, pp. 358–368. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-87193-2_34

    Chapter  Google Scholar 

  16. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  17. Wang, X., Girshick, R., Gupta, A., He, K.: Non-local neural networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7794–7803 (2018)

    Google Scholar 

  18. Lee, C.Y., Xie, S., Gallagher, P., Zhang, Z., Tu, Z.: Deeply-supervised nets. In: Artificial Intelligence and Statistics, pp. 562–570. PMLR (2015)

    Google Scholar 

  19. Salehi, S.S.M., Erdogmus, D., Gholipour, A.: Tversky loss function for image segmentation using 3D fully convolutional deep networks. In: Wang, Q., Shi, Y., Suk, H.-I., Suzuki, K. (eds.) MLMI 2017. LNCS, vol. 10541, pp. 379–387. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-67389-9_44

    Chapter  Google Scholar 

  20. Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980 (2014)

  21. Zhou, Z., Rahman Siddiquee, M.M., Tajbakhsh, N., Liang, J.: UNet++: a nested U-Net architecture for medical image segmentation. In: Stoyanov, D., et al. (eds.) DLMIA/ML-CDS -2018. LNCS, vol. 11045, pp. 3–11. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00889-5_1

    Chapter  Google Scholar 

  22. Jha, D., et al.: ResUNet++: an advanced architecture for medical image segmentation. In: 2019 IEEE International Symposium on Multimedia (ISM), pp. 225–2255. IEEE (2019)

    Google Scholar 

  23. Chen, L.-C., Zhu, Y., Papandreou, G., Schroff, F., Adam, H.: Encoder-decoder with atrous separable convolution for semantic image segmentation. In: Ferrari, V., Hebert, M., Sminchisescu, C., Weiss, Y. (eds.) ECCV 2018. LNCS, vol. 11211, pp. 833–851. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01234-2_49

    Chapter  Google Scholar 

  24. Ypsilantis, P.P., Montana, G.: Learning what to look in chest x-rays with a recurrent visual attention model. arXiv preprint arXiv:1701.06452 (2017)

  25. Gu, R., et al.: CA-Net: comprehensive attention convolutional neural networks for explainable medical image segmentation. IEEE Trans. Med. Imaging 40(2), 699–711 (2020)

    Article  Google Scholar 

  26. Fan, D.-P., et al.: PraNet: parallel reverse attention network for polyp segmentation. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12266, pp. 263–273. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59725-2_26

    Chapter  Google Scholar 

  27. Song, J., et al.: Global and local feature reconstruction for medical image segmentation. IEEE Trans. Med. Imaging 41(9), 2273–2284 (2022)

    Google Scholar 

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Acknowledgements

This work was supported by the National Natural Science Fund for Distinguished Young Scholar under Grants No. 62025601.

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Correspondence to Lei Zhang .

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Yu, Y., Zhang, L., Shu, X., Wang, Z., Chen, C., Xu, J. (2022). A Coarse-to-Fine Network for Craniopharyngioma Segmentation. In: Lian, C., Cao, X., Rekik, I., Xu, X., Cui, Z. (eds) Machine Learning in Medical Imaging. MLMI 2022. Lecture Notes in Computer Science, vol 13583. Springer, Cham. https://doi.org/10.1007/978-3-031-21014-3_10

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  • DOI: https://doi.org/10.1007/978-3-031-21014-3_10

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