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Conceptual Modeling-Based Cardiopathies Data Management

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Advances in Conceptual Modeling (ER 2022)

Abstract

Familiar cardiopathies are a group of heterogeneous disorders that affect the heart. Although their origin has a strong genetic component, most patients’ variations have not been reported and are not classified. Thus, cardiologists struggle to assess whether the origin of the disease is genetic and are unable to provide an appropriate early diagnosis. Providing an enriched context for understanding the role of such variations in these disorders is crucial. This work reports the identification of the conceptual dimensions that are required to provide such context. Then, we instantiate the identified conceptual dimensions in a use case. Finally, the instantiated dimensions are integrated to provide semantic interoperability.

Supported by ACIF/2021/117, INBIO2021/AP2021-05, MICIN/AEI/10.13039/501100011033, and INNEST/2021/57 grants.

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Notes

  1. 1.

    Through grants INBIO 2021/AP2021-05 and INNEST/2021/57.

  2. 2.

    Ions trigger some processes of the heart’s muscle contraction while ATP and ADP are used by cells to obtain energy.

References

  1. Barriales-Villa, R., et al.: Plan of action for inherited cardiovascular diseases: synthesis of recommendations and action algorithms. Rev. Esp. Cardiol. 69(3), 300–309 (2016). https://doi.org/10.1016/j.rec.2015.11.029

    Article  Google Scholar 

  2. Ciarambino, T., et al.: Cardiomyopathies: an overview. Int. J. Mol. Sci. 22(14), 7722 (2021). https://doi.org/10.3390/ijms22147722

    Article  Google Scholar 

  3. García S., A., Casamayor, J.C., Pastor, O.: ISGE: a conceptual model-based method to correctly manage genome data. In: Nurcan, S., Korthaus, A. (eds.) CAiSE 2021. LNBIP, vol. 424, pp. 47–54. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-79108-7_6

    Chapter  Google Scholar 

  4. García S., A., et al.: A conceptual model-based approach to improve the representation and management of omics data in precision medicine. IEEE Access 9, 154071–154085 (2021). https://doi.org/10.1109/ACCESS.2021.3128757

  5. Guizzardi, G., Wagner, G., Almeida, J.P.A., Guizzardi, R.S.: Towards ontological foundations for conceptual modeling: the unified foundational ontology (UFO) story. Appl. Ontology 10(3–4), 259–271 (2015)

    Article  Google Scholar 

  6. Hall, J.E., Guyton, A.C.: Guyton and Hall Textbook of Medical Physiology. Saunders/Elsevier, Philadelphia (2011)

    Google Scholar 

  7. Henderson, C.A., et al.: Overview of the muscle cytoskeleton. Compr. Physiol. 7(3), 891–944 (2017). https://doi.org/10.1002/cphy.c160033

    Article  Google Scholar 

  8. Krans, J.L.: The sliding filament theory of muscle contraction. Nat. Educ. 3(9), 66 (2010)

    Google Scholar 

  9. Morimoto, S.: Sarcomeric proteins and inherited cardiomyopathies. Cardiovasc. Res. 77(4), 659–666 (2008). https://doi.org/10.1093/cvr/cvm084

    Article  Google Scholar 

  10. Perry, E., et al.: Classification of the cardiomyopathies: a position statement from the European society of cardiology working group on myocardial and pericardial diseases. Eur. Heart J. 29(2), 270–276 (2008). https://doi.org/10.1093/eurheartj/ehm585

    Article  MathSciNet  Google Scholar 

  11. van der Velden, J., Stienen, G.J.: Cardiac disorders and pathophysiology of sarcomeric proteins. Physiol. Rev. 99(1), 381–426 (2019). https://doi.org/10.1152/physrev.00040.2017

    Article  Google Scholar 

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Correspondence to Mireia Costa .

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Costa, M., García S., A., Pastor, O. (2022). Conceptual Modeling-Based Cardiopathies Data Management. In: Guizzardi, R., Neumayr, B. (eds) Advances in Conceptual Modeling. ER 2022. Lecture Notes in Computer Science, vol 13650. Springer, Cham. https://doi.org/10.1007/978-3-031-22036-4_2

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  • DOI: https://doi.org/10.1007/978-3-031-22036-4_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-22035-7

  • Online ISBN: 978-3-031-22036-4

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