Skip to main content

Multi-modal Transformer for Brain Tumor Segmentation

  • Conference paper
  • First Online:
Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (BrainLes 2022)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 13769))

Included in the following conference series:

Abstract

Segmentation of brain tumors from multiple MRI modalities is necessary for successful disease diagnosis and clinical treatment. In recent years, Transformer-based networks with the self-attention mechanism have been proposed. But they do not show the performance beyond the U-shaped fully convolutional network. In this paper, we apply HFTrans network to the brain tumor segmentation task of BraTS 2022 challenge by focusing on the multi-modalities of MRI with the benefits of Transformer. By applying BraTS-specific modifications of preprocessing, aggressive data augmentation, and postprocessing, our method shows superior results in comparisons between previous best performers. We show that the final result on the BraTS 2022 validation dataset achieves dice scores of 82.94%, 85.48%, and 92.44% and Hausdorff distances of 14.55 mm, 12.96 mm, and 3.77 mm for enhancing tumor, tumor core, and whole tumor, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bakas, S., et al.: Segmentation labels and radiomic features for the pre-operative scans of the TCGA-GBM collection (2017). https://doi.org/10.7937/K9/TCIA.2017.KLXWJJ1Q

  2. Bakas, S., et al.: Segmentation labels and radiomic features for the pre-operative scans of the TCGA-LGG collection (2017). https://doi.org/10.7937/K9/TCIA.2017.GJQ7R0EF

  3. Bakas, S., et al.: Advancing the cancer genome atlas glioma MRI collections with expert segmentation labels and radiomic features. Sci. Data 4(1), 1–13 (2017)

    Article  Google Scholar 

  4. Bakas, S., et al.: Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the brats challenge. arXiv preprint arXiv:1811.02629 (2018)

  5. Chen, J., et al.: Transunet: transformers make strong encoders for medical image segmentation. arXiv preprint arXiv:2102.04306 (2021)

  6. Cho, J., Park, J.: Hybrid-fusion transformer for multisequence MRI. In: Medical Imaging and Computer-Aided Diagnosis. Springer, Cham (2022, in press)

    Google Scholar 

  7. Dosovitskiy, A., et al.: An image is worth 16x16 words: transformers for image recognition at scale. arXiv preprint arXiv:2010.11929 (2020)

  8. Hatamizadeh, A., Nath, V., Tang, Y., Yang, D., Roth, H., Xu, D.: Swin UNETR: swin transformers for semantic segmentation of brain tumors in MRI images. arXiv preprint arXiv:2201.01266 (2022)

  9. Isensee, F., Jäger, P.F., Full, P.M., Vollmuth, P., Maier-Hein, K.H.: nnU-Net for brain tumor segmentation. In: Crimi, A., Bakas, S. (eds.) BrainLes 2020. LNCS, vol. 12659, pp. 118–132. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-72087-2_11

    Chapter  Google Scholar 

  10. Isensee, F., et al.: nnu-net: self-adapting framework for u-net-based medical image segmentation. arXiv preprint arXiv:1809.10486 (2018)

  11. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)

    Google Scholar 

  12. Luu, H.M., Park, S.H.: Extending nn-unet for brain tumor segmentation. arXiv preprint arXiv:2112.04653 (2021)

  13. Menze, B.H., et al.: The multimodal brain tumor image segmentation benchmark (BRATS). IEEE Trans. Med. Imaging 34(10), 1993–2024 (2014)

    Article  Google Scholar 

  14. Milletari, F., Navab, N., Ahmadi, S.A.: V-net: fully convolutional neural networks for volumetric medical image segmentation. In: 2016 Fourth International Conference on 3D Vision (3DV), pp. 565–571. IEEE (2016)

    Google Scholar 

  15. Pérez-García, F., Sparks, R., Ourselin, S.: Torchio: a python library for efficient loading, preprocessing, augmentation and patch-based sampling of medical images in deep learning. Comput. Methods Programs Biomed. 106236 (2021). https://doi.org/10.1016/j.cmpb.2021.106236. https://www.sciencedirect.com/science/article/pii/S0169260721003102

  16. Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. CoRR abs/1505.04597 (2015). http://arxiv.org/abs/1505.04597

  17. Wang, W., Chen, C., Ding, M., Yu, H., Zha, S., Li, J.: TransBTS: multimodal brain tumor segmentation using transformer. In: de Bruijne, M., et al. (eds.) MICCAI 2021. LNCS, vol. 12901, pp. 109–119. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-87193-2_11

    Chapter  Google Scholar 

Download references

Acknowledgements

This research was supported by the Capacity Enhancement Program for Scientific and Cultural Exhibition Services through the National Research Foundation of Korea (NRF) funded by Ministry of Science and ICT (No. NRF-2018X1A3A1069693) and Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government (MOTIE) (20201510300280, Development of a remote dismantling training system with force-torque responding virtual nuclear power plant).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jinah Park .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Cho, J., Park, J. (2023). Multi-modal Transformer for Brain Tumor Segmentation. In: Bakas, S., et al. Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2022. Lecture Notes in Computer Science, vol 13769. Springer, Cham. https://doi.org/10.1007/978-3-031-33842-7_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-33842-7_12

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-33841-0

  • Online ISBN: 978-3-031-33842-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics