Skip to main content

Training Strategies for Covid-19 Severity Classification

  • Conference paper
  • First Online:
Bioinformatics and Biomedical Engineering (IWBBIO 2023)

Abstract

The COVID-19 pandemic has posed a significant public health challenge on a global scale. It is imperative that we continue to undertake research in order to identify early markers of disease progression, enhance patient care through prompt diagnosis, identification of high-risk patients, early prevention, and efficient allocation of medical resources. In this particular study, we obtained 100 5-min electrocardiograms (ECGs) from 50 COVID-19 volunteers in two different positions, namely upright and supine, who were categorized as either moderately or critically ill. We used classification algorithms to analyze heart rate variability (HRV) metrics derived from the ECGs of the volunteers with the goal of predicting the severity of illness. Our study choose a configuration pro SVC that achieved 76% of accuracy, and 0.84 on F1 Score in predicting the severity of Covid-19 based on HRV metrics.

Grant FUNCAP (Ceará State Foundation for the Support of Scientific and Technological Development) PS1-0186-00439.01.00/21.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Hosseini, E., et al.: The novel coronavirus Disease-2019(COVID-19): mechanism of action, detection and recent therapeutic strategies. Virology 551, 1–9 (2020)

    Article  Google Scholar 

  2. Lai, C., Lam, W.: Laboratory testing for the diagnosis of COVID-19. Biochem. Biophys. Res. Commun. 538, 226–230 (2021)

    Article  CAS  PubMed  Google Scholar 

  3. Wang, S., et al.: A fully automatic deep learning system for COVID-19 diagnostic and prognostic analysis. Eur. Respir. J. 56(2), 2000775 (2020). https://doi.org/10.1183/13993003.00775-2020

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Khuzani, Z., et al.: COVID-classifier: an automated machine learning model to assist in the diagnosis of COVID-19 infection in chest X-ray images. Sci. Rep. J. 6(11) (2021). https://doi.org/10.1038/s41598-021-88807-2

  5. Shaffer, F., McCraty, R., Zerr, C. L.: A healthy heart is not a metronome: an integrative review of the heart’s anatomy and heart rate variability. Front. Psychol. 5, 1040. https://doi.org/10.3389/fpsyg.2014.01040

  6. Mccraty, R., Shaffer, F.: Heart rate variability: new perspectives on physiological mechanisms, assessment of self-regulatory capacity, and health risk. Glob. Adv. Health Med. 4(1), 46–61 (2015). https://doi.org/10.7453/gahmj.2014.073

  7. Yan, X., et al.: Clinical characteristics and prognosis of 218 patients with COVID-19: a retrospective study based on clinical classification. Front. Med. 7, 485 (2020)

    Article  Google Scholar 

  8. Felber Dietrich, D., Schindler, C., Schwartz, J., et al.: Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study. Europace 8(7), 521–529 (2006). https://doi.org/10.1093/europace/eul063

  9. Brown, S.J., Brown, J.A.: Resting and postexercise cardiac autonomic control in trained master athletes. J. Physiol. Sci. 57(1), 23–29 (2007). https://doi.org/10.2170/physiolsci.RP012306

  10. World Medical Association: World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 310(20), 2191–2194 (2013). https://doi.org/10.1001/jama.2013.281053

  11. Vonesch, C., Blu, T., Unser, M.: Generalized daubechies wavelet families. IEEE Trans. Signal Process. 55(9), 4415–4429 (2007). https://doi.org/10.1109/TSP.2007.896255

    Article  Google Scholar 

  12. Madeiro, J.P.V.: An innovative approach of QRS segmentation based on first-derivative, Hilbert and Wavelet Transforms. Med. Eng. Phys. 34(9), 1236–1246 (2012)

    Article  PubMed  Google Scholar 

  13. Kunjan, S., et al.: The necessity of leave one subject out (LOSO) cross validation for EEG disease diagnosis. In: Mahmud, M., Kaiser, M.S., Vassanelli, S., Dai, Q., Zhong, N. (eds.) BI 2021. LNCS (LNAI), vol. 12960, pp. 558–567. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-86993-9_50

    Chapter  Google Scholar 

  14. Pedregosa, F., et al.: Scikit-learn: machine learning in python. J. Mach. Learn. Res. 12, 2825–2830 (2011)

    Google Scholar 

  15. Shaffer, F., Meehan, Z.M., Zerr, C.L.: A critical review of ultra-short-term heart rate variability norms research. Front. Neurosci. 14, 594880 (2020)

    Article  PubMed  PubMed Central  Google Scholar 

  16. Silva, L., et al.: Heart rate variability as a biomarker in patients with Chronic Chagas Cardiomyopathy with or without concomitant digestive involvement and its relationship with the Rassi score. Biomed. Eng. Online 21(1), 44 (2022). https://doi.org/10.1186/s12938-022-01014-6

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Pordeus .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Pordeus, D. et al. (2023). Training Strategies for Covid-19 Severity Classification. In: Rojas, I., Valenzuela, O., Rojas Ruiz, F., Herrera, L.J., Ortuño, F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2023. Lecture Notes in Computer Science(), vol 13919. Springer, Cham. https://doi.org/10.1007/978-3-031-34953-9_40

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-34953-9_40

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-34952-2

  • Online ISBN: 978-3-031-34953-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics