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Noise2Aliasing: Unsupervised Deep Learning for View Aliasing and Noise Reduction in 4DCBCT

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Medical Image Computing and Computer Assisted Intervention – MICCAI 2023 (MICCAI 2023)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 14229))

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Abstract

Respiratory Correlated Cone Beam Computed Tomography (4DCBCT) is a technique used to address respiratory motion artifacts that affect reconstruction quality, especially for the thorax and upper-abdomen. 4DCBCT sorts the acquired projection images in multiple respiratory correlated bins. This technique results in the emergence of aliasing artifacts caused by the low number of projection images per bin, which severely impacts the image quality and limits downstream use. Previous attempts to address this problem relied on traditional algorithms, while only recently deep learning techniques are being employed.

In this work, we propose Noise2Aliasing, which reduces both view-aliasing and statistical noise present in 4DCBCT scans. Using a fundamental property of the FDK reconstruction algorithm, and prior results from the literature, we prove mathematically the ability of the method to work and specify the underlying assumptions.

We apply the method to a public dataset and to an in-house dataset and show that it matches the performance of a supervised approach and outperforms it when measurement noise is present in the data.

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References

  1. Dawson, L.A., Jaffray, D.A.: Advances in image-guided radiation therapy. J. Clin. Oncol. 25(8), 938–946 (2007)

    Article  Google Scholar 

  2. Feldkamp, L.A., Davis, L.C., Kress, J.W.: Practical cone-beam algorithm. Josa a 1(6), 612–619 (1984)

    Article  Google Scholar 

  3. Hastie, T., Tibshirani, R., Friedman, J.H., Friedman, J.H.: The Elements of Statistical Learning: Data Mining, Inference, and Prediction, vol. 2. Springer, New York (2009)

    Book  MATH  Google Scholar 

  4. Hendriksen, A.A., Pelt, D.M., Batenburg, K.J.: Noise2Inverse: self-supervised deep convolutional denoising for tomography. IEEE Trans. Comput. Imaging 6, 1320–1335 (2020). https://doi.org/10.1109/TCI.2020.3019647

    Article  MathSciNet  Google Scholar 

  5. Lehtinen, J., et al.: Noise2Noise: learning image restoration without clean data. In: Proceedings of the 35th International Conference on Machine Learning, pp. 2965–2974. PMLR, July 2018

    Google Scholar 

  6. Madesta, F., Sentker, T., Gauer, T., Werner, R.: Self-contained deep learning-based boosting of 4D cone-beam CT reconstruction. Med. Phys. 47(11), 5619–5631 (2020). https://doi.org/10.1002/mp.14441

    Article  Google Scholar 

  7. Mory, C., Janssens, G., Rit, S.: Motion-aware temporal regularization for improved 4d cone-beam computed tomography. Phys. Med. Biol. 61(18), 6856 (2016)

    Article  Google Scholar 

  8. Pelt, D.M., Sethian, J.A.: A mixed-scale dense convolutional neural network for image analysis. Proc. Natl. Acad. Sci. 115(2), 254–259 (2018)

    Article  MathSciNet  Google Scholar 

  9. Quinto, E.T.: An introduction to x-ray tomography and radon transforms. In: Proceedings of Symposia in Applied Mathematics, vol. 63, p. 1 (2006)

    Google Scholar 

  10. Ren, L., et al.: A novel digital tomosynthesis (DTS) reconstruction method using a deformation field map. Med. Phys. 35(7Part1), 3110–3115 (2008)

    Article  Google Scholar 

  11. Riblett, M.J., Christensen, G.E., Weiss, E., Hugo, G.D.: Data-driven respiratory motion compensation for four-dimensional cone-beam computed tomography (4D-CBCT) using GroupWise deformable registration. Med. Phys. 45(10), 4471–4482 (2018)

    Article  Google Scholar 

  12. Rit, S., van Herk, M., Zijp, L., Sonke, J.J.: Quantification of the variability of diaphragm motion and implications for treatment margin construction. Int. J. Radiat. Oncol. * Biol.* Phys. 82(3), e399–e407 (2012)

    Google Scholar 

  13. Rit, S., Oliva, M.V., Brousmiche, S., Labarbe, R., Sarrut, D., Sharp, G.C.: The reconstruction toolkit (RTK), an open-source cone-beam CT reconstruction toolkit based on the insight toolkit (ITK). J. Phys. Conf. Ser. 489, 012079 (2014)

    Article  Google Scholar 

  14. Rit, S., Wolthaus, J.W., van Herk, M., Sonke, J.J.: On-the-fly motion-compensated cone-beam CT using an a priori model of the respiratory motion. Med. Phys. 36(6Part1), 2283–2296 (2009)

    Article  Google Scholar 

  15. Shieh, C.C., et al.: Spare: sparse-view reconstruction challenge for 4d cone-beam CT from a 1-min scan. Med. Phys. 46(9), 3799–3811 (2019)

    Article  Google Scholar 

  16. Sonke, J.J., Zijp, L., Remeijer, P., van Herk, M.: Respiratory correlated cone beam CT: respiratory correlated cone beam CT. Med. Phys. 32(4), 1176–1186 (2005). https://doi.org/10.1118/1.1869074

    Article  Google Scholar 

  17. Wang, Z., Bovik, A.C., Sheikh, H.R., Simoncelli, E.P.: Image quality assessment: from error visibility to structural similarity. IEEE Trans. Image Process. 13(4), 600–612 (2004)

    Article  Google Scholar 

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Acknowledgements and Disclosures

We thank Celia Juan de la Cruz, Nikita Moriakov, Xander Staal, and Jonathan Mason for helping during the development of this work.

This work was funded by ROV with grant number PPS2102 and Elekta Oncology AB and was supported by an institutional grant of the Dutch Cancer Society and the Dutch Ministry of Health.

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Correspondence to Samuele Papa .

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Papa, S., Gavves, E., Sonke, JJ. (2023). Noise2Aliasing: Unsupervised Deep Learning for View Aliasing and Noise Reduction in 4DCBCT. In: Greenspan, H., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023. MICCAI 2023. Lecture Notes in Computer Science, vol 14229. Springer, Cham. https://doi.org/10.1007/978-3-031-43999-5_46

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  • DOI: https://doi.org/10.1007/978-3-031-43999-5_46

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  • Online ISBN: 978-3-031-43999-5

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