Skip to main content
SpringerLink
Log in

Dictionary Matching Based 2D Thin Slice Generalized Slice-dithered Enhanced Resolution (gSlider) Variable Flip Angle T1 Mapping

  • Conference paper
  • First Online:
Image and Graphics (ICIG 2023)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 14359))

Included in the following conference series:

  • 248 Accesses

Abstract

The accurate estimation of the T1 parameter plays an important role in many fields such as the diagnosis of neurological disorders in clinical practice and dynamic contrast-enhanced studies of tissue perfusion. Many T1 mapping methods suffer from long scan times and inaccurate estimation. As a rapid T1 mapping method, 2D variable flip angle (VFA) enables high temporal and in-plane spatial resolution acquisition. However, 2D VFA is sensitive to inhomogeneity of RF transmit field (B1+) and RF slice profile imperfection, which introduces excitation flip angle variations both in-plane and slice direction, and leads to T1 estimation bias. In this paper, we developed a dictionary matching based 2D VFA T1 mapping method by Bloch equation simulation incorporating B1+ correction and slice profile correction to reduce the T1 estimation bias. To further improve the quality of thin slice T1 mapping, a slab RF encoding generalized slice-dithered enhanced resolution (gSlider) acquisition was introduced and combined with 2D VFA and dictionary matching. The 1.5 mm thin slice T1 mappings showed high accuracy as compared with the inverse recovery (IR) gold standard method in phantom experiments, and show similar image quality as 3 mm thick result in in-vivo experiments.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 74.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Heule, R., Pfeuffer, J., Meyer, C.H., Bieri, O.: Simultaneous B1 and T1 mapping using spiral multislice variable flip angle acquisitions for whole-brain coverage in less than one minute. Magn. Reson. Med. 81, 1876–1889 (2019)

    Article  Google Scholar 

  2. Kober, T., et al.: MP2RAGE multiple sclerosis magnetic resonance imaging at 3 T. Invest. Radiol. 47, 346–352 (2012)

    Article  Google Scholar 

  3. Baudrexel, S., et al.: Quantitative mapping of T1 and T2* discloses nigral and brainstem pathology in early Parkinson’s disease. Neuroimage 51, 512–520 (2010)

    Article  Google Scholar 

  4. Christensen, K.A., Grant, D.M., Schulman, E.M., Walling, C.: Optimal determination of relaxation times of fourier transform nuclear magnetic resonance. Determination of spin-lattice relaxation times in chemically polarized species. J. Phys. Chem. 78(19), 1971–1977 (1974)

    Google Scholar 

  5. Hey, S., et al.: Simultaneous T1 measurements and proton resonance frequency shift based thermometry using variable flip angles. Magn. Reson. Med. 67, 457–463 (2012)

    Article  Google Scholar 

  6. Hurley, S.A., Yarnykh, V.L., Johnson, K.M., Field, A.S., Alexander, A.L., Samsonov, A.A.: Simultaneous variable flip angle–actual flip angle imaging method for improved accuracy and precision of three-dimensional T1 and B1 measurements. Magn. Reson. Med. 68, 54–64 (2012)

    Article  Google Scholar 

  7. Heule, R., Ganter, C., Bieri, O.: Variable flip angle T1 mapping in the human brain with reduced T2 sensitivity using fast radiofrequency-spoiled gradient echo imaging: VFA T1 Mapping in the Human Brain with Reduced T 2 Sensitivity. Magn. Reson. Med. 75, 1413–1422 (2016)

    Article  Google Scholar 

  8. Svedin, B.T., Parker, D.L.: Technical Note: the effect of 2D excitation profile on T1 measurement accuracy using the variable flip angle method with an average flip angle assumption. Med. Phys. 44, 5930–5937 (2017)

    Article  Google Scholar 

  9. Dieringer, M.A., et al.: Rapid parametric mapping of the longitudinal relaxation time T1 using two-dimensional variable flip angle magnetic resonance imaging at 1.5 Tesla, 3 Tesla, and 7 Tesla. PLoS ONE 9, e91318 (2014)

    Google Scholar 

  10. Siversson, C., et al.: Effects of B1 inhomogeneity correction for three-dimensional variable flip angle T1 measurements in hip dGEMRIC at 3 T and 1.5 T. Magn. Reson. Med. 67, 1776–1781 (2012)

    Google Scholar 

  11. Boudreau, M., Tardif, C.L., Stikov, N., Sled, J.G., Lee, W., Pike, G.B.: B1 mapping for bias-correction in quantitative T1 imaging of the brain at 3T using standard pulse sequences. J. Magn. Reson. Imaging 46, 1673–1682 (2017)

    Article  Google Scholar 

  12. Ma, D., et al.: Magnetic resonance fingerprinting. Nature 495, 187–192 (2013)

    Article  Google Scholar 

  13. Setsompop, K., et al.: High-resolution in vivo diffusion imaging of the human brain with generalized slice dithered enhanced resolution: simultaneous multislice (gSlider-SMS): high-Resolution Diffusion Imaging With gSlider-SMS. Magn. Reson. Med. 79, 141–151 (2018)

    Article  Google Scholar 

  14. Cao, X., et al.: Efficient T2 mapping with blip-up/down EPI and gSlider-SMS (T2-BUDA-gSlider). Magn. Reson. Med. 86, 2064–2075 (2021)

    Article  Google Scholar 

  15. Cheng, H.-L.M., Wright, G.A.: Rapid high-resolution T1 mapping by variable flip angles: accurate and precise measurements in the presence of radiofrequency field inhomogeneity. Magn. Reson. Med. 55, 566–574 (2006)

    Article  Google Scholar 

  16. Deoni, S.C.L., Rutt, B.K., Peters, T.M.: Rapid combined T1 and T2 mapping using gradient recalled acquisition in the steady state. Magn. Reson. Med. 49, 515–526 (2003)

    Article  Google Scholar 

  17. Wang, H.Z., Riederer, S.J., Lee, J.N.: Optimizing the precision in T1 relaxation estimation using limited flip angles. Magn. Reson. Med. 5, 399–416 (1987)

    Article  Google Scholar 

  18. Preibisch, C., Deichmann, R.: Influence of RF spoiling on the stability and accuracy of T1 mapping based on spoiled FLASH with varying flip angles. Magn. Reson. Med. 61, 125–135 (2009)

    Article  Google Scholar 

  19. Chung, S., Kim, D., Breton, E., Axel, L.: Rapid B 1 + mapping using a preconditioning RF pulse with TurboFLASH readout. Magn. Reson. Med. 64, 439–446 (2010)

    Article  Google Scholar 

  20. Liao, C., et al.: High-fidelity, high-isotropic-resolution diffusion imaging through gSlider acquisition with and T 1 corrections and integrated Δ B 0 / Rx shim array. Magn. Reson. Med. 83, 56–67 (2020)

    Article  Google Scholar 

  21. Haldar, J.P., Liu, Y., Liao, C., Fan, Q., Setsompop, K.: Fast submillimeter diffusion MRI using gSlider-SMS and SNR-enhancing joint reconstruction. Magn. Reson. Med. 84, 762–776 (2020)

    Article  Google Scholar 

  22. Liao, C., et al.: Distortion-free, high-isotropic-resolution diffusion MRI with gSlider BUDA-EPI and multicoil dynamic B0 shimming. Magn. Reson. Med. 86, 791–803 (2021)

    Article  Google Scholar 

  23. Ramos-Llordén, G., et al.: High-fidelity, accelerated whole-brain submillimeter in vivo diffusion MRI using gSlider-spherical ridgelets (gSlider-SR). Magn. Reson. Med. 84, 1781–1795 (2020)

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported in part by the National Key Research and Development Program of China (No: 2020AAA0109502), by the National Natural Science Foundation of China (No: U1809204, 61701436), and by the Zhejiang Provincial Natural Science Foundation of China (No: LY22F010007).

Author information

Authors and Affiliations

  1. State Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, 310027, China

    Yuting Chen, Huafeng Liu & Huihui Ye

Authors
  1. Yuting Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Huafeng Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Huihui Ye
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Huihui Ye .

Editor information

Editors and Affiliations

  1. Dalian University of Technology, Dalian, China

    Huchuan Lu

  2. University of Sydney, Sydney, NSW, Australia

    Wanli Ouyang

  3. Shenzhen University, Shenzhen, China

    Hui Huang

  4. Tsinghua University, Beijing, China

    Jiwen Lu

  5. Dalian University of Technology, Dalian, China

    Risheng Liu

  6. Institute of Automation, CAS, Beijing, China

    Jing Dong

  7. University of Technology Sydney, Sydney, NSW, Australia

    Min Xu

Ethics declarations

This study was approved by the Ethic Review Board of Zhejiang University College of Biomedical Engineering and Instrument Science (No. 2022-IRB-02). And all the volunteers were given informed approval before scanning.

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Chen, Y., Liu, H., Ye, H. (2023). Dictionary Matching Based 2D Thin Slice Generalized Slice-dithered Enhanced Resolution (gSlider) Variable Flip Angle T1 Mapping. In: Lu, H., et al. Image and Graphics . ICIG 2023. Lecture Notes in Computer Science, vol 14359. Springer, Cham. https://doi.org/10.1007/978-3-031-46317-4_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-46317-4_9

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-46316-7

  • Online ISBN: 978-3-031-46317-4

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics

Search

Navigation