Abstract
Accurate coronary vessels segmentation from invasive coronary angiography (ICA) is essential for diagnosis and treatment planning for patients with coronary stenosis. Current machine learning-based approaches primarily utilise convolutional neural networks (CNNs), which heavily focus on the local vessels features and ignore the geometric structures such as the shapes and directions of vessels. This limits the machine understandability of ICA images and creates a bottleneck for improvements of computer-generated segmentation quality, including unstable generalisation ability in low contrast areas and disconnection in vascular structures. To address these issues, we propose a fusion of Graph Attention Network (GAT) and CNN to assist in the learning of global geometric information during coronary vessels segmentation. We train and evaluate the proposed method on a large-scale ICA dataset and demonstrate that combining GAT into a unified network yields improved segmentation performance. Additionally, we utilise specific metrics to demonstrate the achieved improvements, as they offer greater potential for future research and exploration.
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References
Banerjee, A., Choudhury, R.P., Grau, V.: Optimized rigid motion correction from multiple non-simultaneous x-ray angiographic projections. In: Deka, B., Maji, P., Mitra, S., Bhattacharyya, D.K., Bora, P.K., Pal, S.K. (eds.) PReMI 2019. LNCS, vol. 11942, pp. 61–69. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-34872-4_7
Banerjee, A., Galassi, F., Zacur, E., De Maria, G.L., Choudhury, R.P., Grau, V.: Point-cloud method for automated 3D coronary tree reconstruction from multiple non-simultaneous angiographic projections. IEEE Trans. Med. Imaging 39(4), 1278–1290 (2020)
Banerjee, A., Kharbanda, R.K., Choudhury, R.P., Grau, V.: Automated motion correction and 3d vessel centerlines reconstruction from non-simultaneous angiographic projections. In: Pop, M., et al. (eds.) STACOM 2018. LNCS, vol. 11395, pp. 12–20. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-12029-0_2
Fan, J., Yang, J., Wang, Y., et al.: Multichannel fully convolutional network for coronary artery segmentation in x-ray angiograms. IEEE Access 6, 44635–44643 (2018)
Hao, D., et al.: Sequential vessel segmentation via deep channel attention network. Neural Netw. 128, 172–187 (2020)
He, H., Banerjee, A., Beetz, M., Choudhury, R.P., Grau, V.: Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function. In: 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI), pp. 1–5 (2022)
Hong, D., Gao, L., Yao, J., Zhang, B., Plaza, A., Chanussot, J.: Graph convolutional networks for hyperspectral image classification. IEEE Trans. Geosci. Remote Sens. 59(7), 5966–5978 (2020)
Kipf, T.N., Welling, M.: Semi-supervised classification with graph convolutional networks (2017)
Kočka, V.: The coronary angiography - an old-timer in great shape. Cor Vasa 57(6), e419–e424 (2015)
Lan, Y., Xiang, Y., Zhang, L.: An elastic interaction-based loss function for medical image segmentation. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12265, pp. 755–764. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59722-1_73
Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)
Maninis, K.-K., Pont-Tuset, J., Arbeláez, P., Van Gool, L.: Deep retinal image understanding. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 140–148. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_17
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Shen, Y., Zhou, B., Xiong, X., Gao, R., Wang, Y.G.: How GNNs facilitate CNNs in mining geometric information from large-scale medical images (2022)
Shin, S.Y., Lee, S., Yun, I.D., Lee, K.M.: Deep vessel segmentation by learning graphical connectivity. Med. Image Anal. 58, 101556 (2019)
Tsao, C.W., et al.: Heart disease and stroke statistics-2022 update: a report from the American heart association. Circulation 145(8), e153–e639 (2022)
Vaduganathan, M., Mensah, G.A., Turco, J.V., Fuster, V., Roth, G.A.: The global burden of cardiovascular diseases and risk. J. Am. Coll. Cardiol. 80(25), 2361–2371 (2022)
Vasudevan, V., Bassenne, M., Islam, M.T., Xing, L.: Image classification using graph neural network and multiscale wavelet superpixels. Pattern Recogn. Lett. 166, 89–96 (2023)
Veličković, P., Cucurull, G., Casanova, A., Romero, A., Liò, P., Bengio, Y.: Graph attention networks (2018)
Xie, G.S., Liu, J., Xiong, H., Shao, L.: Scale-aware graph neural network for few-shot semantic segmentation. In: 2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), pp. 5471–5480 (2021)
Youssef, R., Ricordeau, A., Sevestre-Ghalila, S., Benazza-Benyahya, A.: Evaluation protocol of skeletonization applied to grayscale curvilinear structures. In: 2015 International Conference on Digital Image Computing: Techniques and Applications (DICTA), pp. 1–6 (2015)
Zhang, J., Gu, R., Wang, G., Xie, H., Gu, L.: SS-CADA: a semi-supervised cross-anatomy domain adaptation for coronary artery segmentation. 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI), pp. 1227–1231 (2021)
Acknowledgments
The authors acknowledge the use of the facilities and services of the Institute of Biomedical Engineering (IBME), Department of Engineering Science, University of Oxford and the use of the University of Oxford Advanced Research Computing (ARC) facility, http://dx.doi.org/10.5281/zenodo.22558, in carrying out this work. AB is a Royal Society University Research Fellow and is supported by the Royal Society Grant No. URF\(\backslash \)R1\(\backslash \)221314. The works of AB, RPC, and VG were partially supported by the British Heart Foundation (BHF) Project under Grant PG/20/21/35082. The work of VG was supported by the CompBioMed 2 Centre of Excellence in Computational Biomedicine (European Commission Horizon 2020 research and innovation programme, grant agreement No. 823712).
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He, H., Banerjee, A., Choudhury, R.P., Grau, V. (2024). Automated Coronary Vessels Segmentation in X-ray Angiography Using Graph Attention Network. In: Camara, O., et al. Statistical Atlases and Computational Models of the Heart. Regular and CMRxRecon Challenge Papers. STACOM 2023. Lecture Notes in Computer Science, vol 14507. Springer, Cham. https://doi.org/10.1007/978-3-031-52448-6_20
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