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XR-Based Serious Game for Assessing Bradykinesia in Patients with Parkinson’s Disease

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Extended Reality (XR Salento 2024)

Abstract

Parkinson’s Disease (PD) is a neurodegenerative disorder that compromises different motor, behavioural and cognitive functions. Recent technological advances have encouraged the development of eXtended Reality (XR) applications for PD, both in diagnostics and therapeutics. In this study, we present a new XR-based serious game designed to assess hand bradykinesia in individuals with PD. The game involves popping randomly generated colored balloons in the real-world environment, requiring players to perform finger-tap gestures within a limited time frame. Game difficulty escalates across levels, introducing simple or complex cognitive dual tasks. Five PD participants participated in the first usability and user experience evaluations. Overall, the participants encountered no significant issues during the game and showed considerable interest in the application. Usability tests indicated optimal usability levels but revealed a high perceived workload among participants. Future research will focus on assessing the efficacy of the proposed XR system through a comprehensive clinical trial.

This work was financially supported by the Italian Ministry of Health, through the project HubLife Science - Digital Health (LSH-DH) PNC-E3-2022-23683267 - DHEAL-COM - CUP E63C22003790001, within the “National Plan for Complementary Investments - Innovative Health Ecosystem” - Unique Investment Code: PNC-E.3.

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References

  1. https://unity.com

  2. https://www.microsoft.com/it-it/hololens

  3. Akram, N., et al.: Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson’s disease: a distal finger tapping test. Sci. Rep. 12(1), 386 (2022)

    Google Scholar 

  4. Arias, P., Robles-García, V., Sanmartín, G., Flores, J., Cudeiro, J.: Virtual reality as a tool for evaluation of repetitive rhythmic movements in the elderly and Parkinson’s disease patients. PLoS ONE 7(1), e30021 (2012)

    Google Scholar 

  5. Balestrino, R., Schapira, A.: Parkinson disease. Eur. J. Neurol. 27(1), 27–42 (2020)

    Google Scholar 

  6. Bangor, A., Kortum, P.T., Miller, J.T.: An empirical evaluation of the system usability scale. Int. J. Hum.-Comput. Interact. 24(6), 574–594 (2008)

    Google Scholar 

  7. Bank, P.J., Marinus, J., Meskers, C.G., de Groot, J.H., van Hilten, J.J.: Optical hand tracking: a novel technique for the assessment of bradykinesia in Parkinson’s disease. Move. Disord. Clin. Pract. 4(6), 875–883 (2017)

    Google Scholar 

  8. Bloem, B.R., Okun, M.S., Klein, C.: Parkinson’s disease. Lancet 397(10291), 2284–2303 (2021)

    Google Scholar 

  9. Canning, C.G., Allen, N.E., Nackaerts, E., Paul, S.S., Nieuwboer, A., Gilat, M.: Virtual reality in research and rehabilitation of gait and balance in Parkinson disease. Nat. Rev. Neurol. 16(8), 409–425 (2020)

    Google Scholar 

  10. Fernández-González, D., Rodriguez-Costa, I., Sanz-Esteban, I., Estrada-Barranco, C.: Therapeutic intervention with virtual reality in patients with Parkinson’s disease for upper limb motor training: a systematic review. Rehabilitacion 57(2), 100751 (2023)

    Google Scholar 

  11. Gulcan, K., Guclu-Gunduz, A., Yasar, E., Ar, U., Sucullu Karadag, Y., Saygili, F.: The effects of augmented and virtual reality gait training on balance and gait in patients with Parkinson’s disease. Acta Neurol. Belg. 123(5), 1917–1925 (2023)

    Google Scholar 

  12. Hart, S.G., Staveland, L.E.: Development of NASA-TLX (task load index): results of empirical and theoretical research. Adv. Psychol. 52, 139–183 (1988). Elsevier

    Google Scholar 

  13. Hoehn, M.M., Yahr, M.D.: Parkinsonism: onset, progression, and mortality. Neurology 17(5), 427–427 (1967)

    Google Scholar 

  14. Kwon, S.H., Park, J.K., Koh, Y.H.: A systematic review and meta-analysis on the effect of virtual reality-based rehabilitation for people with Parkinson’s disease. J. Neuroeng. Rehabil. 20(1), 94 (2023)

    Google Scholar 

  15. Lee, C.Y., Kang, S.J., Hong, S.K., Ma, H.I., Lee, U., Kim, Y.J.: A validation study of a smartphone-based finger tapping application for quantitative assessment of bradykinesia in Parkinson’s disease. PLoS ONE 11(7), e0158852 (2016)

    Google Scholar 

  16. de Oliveira, L.C., et al.: A systematic review of serious games used for rehabilitation of individuals with Parkinson’s disease. Res. Biomed. Eng. 1–17 (2021)

    Google Scholar 

  17. Paraskevopoulos, I.T., Tsekleves, E., Craig, C., Whyatt, C., Cosmas, J.: Design guidelines for developing customised serious games for Parkinson’s disease rehabilitation using bespoke game sensors. Entertain. Comput. 5(4), 413–424 (2014)

    Google Scholar 

  18. Movement Disorder Society Task Force on Rating Scales for Parkinson’s disease. The unified Parkinson’s disease rating scale (UPDRS): status and recommendations. Move. Disord. 18(7), 738–750 (2003)

    Google Scholar 

  19. Pasluosta, C.F., Gassner, H., Winkler, J., Klucken, J., Eskofier, B.M.: An emerging era in the management of Parkinson’s disease: wearable technologies and the internet of things. IEEE J. Biomed. Health Inform. 19(6), 1873–1881 (2015)

    Google Scholar 

  20. Roalf, D.R., et al.: Quantitative assessment of finger tapping characteristics in mild cognitive impairment, Alzheimer’s disease, and Parkinson’s disease. J. Neurol. 265, 1365–1375 (2018)

    Google Scholar 

  21. Rodríguez-Mansilla, J., et al.: Effects of virtual reality in the rehabilitation of Parkinson’s disease: a systematic review. J. Clin. Med. 12(15), 4896 (2023)

    Google Scholar 

  22. Salazar, R.D., et al.: Dual tasking in Parkinson’s disease: cognitive consequences while walking. Neuropsychology 31(6), 613 (2017)

    Google Scholar 

  23. Sánchez-Herrera-Baeza, P., et al.: The impact of a novel immersive virtual reality technology associated with serious games in Parkinson’s disease patients on upper limb rehabilitation: a mixed methods intervention study. Sensors 20(8), 2168 (2020)

    Google Scholar 

  24. Schrepp, M., Hinderks, A., Thomaschewski, J.: Design and evaluation of a short version of the user experience questionnaire (UEQ-S). Int. J. Interact. Multimedia Artif. Intell. 4(6), 103–108 (2017)

    Google Scholar 

  25. Thangavelu, K., et al.: Designing virtual reality assisted psychotherapy for anxiety in older adults living with Parkinson’s disease: integrating literature for scoping. Clin. Gerontol. 45(2), 235–251 (2022)

    Google Scholar 

  26. Tuena, C., et al.: Usability issues of clinical and research applications of virtual reality in older people: a systematic review. Front. Hum. Neurosci. 14, 93 (2020)

    Google Scholar 

  27. Willis, A. W., et al.: Incidence of Parkinson disease in North America. NPJ Parkinson’s Disease 8(1), 170 (2022)

    Google Scholar 

  28. Yun, S.J., Hyun, S.E., Oh, B.M., Seo, H.G.: Fully immersive virtual reality exergames with dual-task components for patients with Parkinson’s disease: a feasibility study. J. Neuroeng. Rehabil. 20(1), 92 (2023)

    Google Scholar 

  29. Zhao, N., et al.: Quality of life in Parkinson’s disease: a systematic review and meta-analysis of comparative studies. CNS Neurosci. Therapeutics 27(3), 270–279 (2021)

    Google Scholar 

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Correspondence to Egidio De Benedetto .

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Arpaia, P. et al. (2024). XR-Based Serious Game for Assessing Bradykinesia in Patients with Parkinson’s Disease. In: De Paolis, L.T., Arpaia, P., Sacco, M. (eds) Extended Reality. XR Salento 2024. Lecture Notes in Computer Science, vol 15028. Springer, Cham. https://doi.org/10.1007/978-3-031-71704-8_8

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  • DOI: https://doi.org/10.1007/978-3-031-71704-8_8

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