Abstract
In this study we set to explore the potentialities of the inter-genomic symbols distance for finding the coding regions in DNA sequences. We use the distance between STOP symbols in the DNA sequence and a chi-square statistic to evaluate the nonhomogeneity of the three possible reading frames. The results of this exploratory study suggest that inter-STOP symbols distance has strong ability to discriminate coding regions.
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© 2013 Springer International Publishing Switzerland
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Bastos, C.A.C., Afreixo, V., Garcia, S.P., Pinho, A.J. (2013). Segmentation of DNA into Coding and Noncoding Regions Based on Inter-STOP Symbols Distances. In: Mohamad, M., Nanni, L., Rocha, M., Fdez-Riverola, F. (eds) 7th International Conference on Practical Applications of Computational Biology & Bioinformatics. Advances in Intelligent Systems and Computing, vol 222. Springer, Heidelberg. https://doi.org/10.1007/978-3-319-00578-2_4
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DOI: https://doi.org/10.1007/978-3-319-00578-2_4
Publisher Name: Springer, Heidelberg
Print ISBN: 978-3-319-00577-5
Online ISBN: 978-3-319-00578-2
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