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International Workshop on Digital Mammography

IWDM 2014: Breast Imaging pp 1–8Cite as

Virtual Clinical Trials for the Assessment of Novel Breast Screening Modalities

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Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 8539))

Abstract

Validation of any imaging system is challenging due to the huge number of system parameters that should be evaluated. The ultimate metric of system performance is a clinical trial. However, the use of clinical trials is limited by cost and duration. We are strong proponents of a preclinical alternative, in the form of Virtual Clinical Trials (VCT), which model human anatomy, image acquisition, display and processing, and image analysis and interpretation. A complete VCT pipeline was envisioned by combining the breast anatomy and image acquisition simulation pipeline developed at the University of Pennsylvania, with the MeVIC image display and observation pipeline developed by researchers at Barco. Today an integrated virtual clinical trial design program, VCTdesigner, and a virtual clinical trial management program, VCTmanager, are freely available (www.VCTworld.org). The pipeline design is flexible and extensible, making it possible to add functionality easily and rapidly. It is our hope that by freely distributing the VCTmanager software, our field can standardize on this platform for running VCT.

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Author information

Authors and Affiliations

  1. Dept. of Radiology, University of Pennsylvania, Philadelphia, PA, USA

    Andrew D. A. Maidment

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  1. Andrew D. A. Maidment
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Editors and Affiliations

  1. Department of Intelligent Image Information, Gifu University Graduate School of Medicine, 1-1 Yanagido, 501-1194, Gifu, Gifu, Japan

    Hiroshi Fujita , Takeshi Hara  & Chisako Muramatsu ,  & 

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© 2014 Springer International Publishing Switzerland

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Maidment, A.D.A. (2014). Virtual Clinical Trials for the Assessment of Novel Breast Screening Modalities. In: Fujita, H., Hara, T., Muramatsu, C. (eds) Breast Imaging. IWDM 2014. Lecture Notes in Computer Science, vol 8539. Springer, Cham. https://doi.org/10.1007/978-3-319-07887-8_1

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  • DOI: https://doi.org/10.1007/978-3-319-07887-8_1

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-07886-1

  • Online ISBN: 978-3-319-07887-8

  • eBook Packages: Computer ScienceComputer Science (R0)

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