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The Relationship of Volumetric Breast Density to Socio-Economic Status in a Screening Population

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Breast Imaging (IWDM 2014)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 8539))

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Abstract

Breast cancer incidence has previously been shown to be greater in women of higher socio-economic status (SES), although the picture is complex due to variations in breast cancer risk factors. We have investigated the relationship between one of the strongest risk factors, breast density, with SES in a population of 6398 post- and peri-menopausal women. Volumetric breast density was measured using QuantraTM and VolparaTM, and SES was based on the Index of Multiple Deprivation (IMD) associated with each woman’s postcode. The mean IMD score was 26.39 (SD 16.7). Our results show a weak but significant association between SES and volumetric breast density; women from more deprived areas have slightly less dense breasts. After controlling for age, BMI and HRT use the relationship remained significant for density measured by VolparaTM (gradient -0.01, p <0.005) but not QuantraTM (gradient -0.007, p=0.07).

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References

  1. Heck, K.E., Pamuk, E.R.: Explaining the relation between education and postmenopausal breast cancer. American Journal of Epidemiology 145(4), 366–372 (1997)

    Article  Google Scholar 

  2. Braaten, T., Weiderpass, E., Kumle, M., Adami, H.O., Lund, E.: Education and risk of breast cancer in the Norwegian‐Swedish women’s lifestyle and health cohort study. International Journal of Cancer 110(4), 579–583 (2004)

    Article  Google Scholar 

  3. Robert, S.A., Trentham-Dietz, A., Hampton, J.M., McElroy, J.A., Newcomb, P.A., Remington, P.L.: Socioeconomic risk factors for breast cancer: distinguishing individual-and community-level effects. Epidemiology 15(4), 442–450 (2004)

    Article  Google Scholar 

  4. Brambilla, D.J., McKinlay, S.M.: A prospective study of factors affecting age at menopause. Journal of Clinical Epidemiology 42(11), 1031–1039 (1989)

    Article  Google Scholar 

  5. Rindfuss, R.R., Morgan, S.P., Offutt, K.: Education and the changing age pattern of American fertility: 1963–1989. Demography 33(3), 277–290 (1996)

    Article  Google Scholar 

  6. Liu, L., Deapen, D., Bernstein, L.: Socioeconomic status and cancers of the female breast and reproductive organs: a comparison across racial/ethnic populations in Los Angeles County, California (United States). Cancer Causes & Control 9(4), 369–380 (1998)

    Article  Google Scholar 

  7. Kaufman, Z., Garstin, W., Hayes, R., Michell, M., Baum, M.: The mammographic parenchymal patterns of women on hormonal replacement therapy. Clinical Radiology 43(6), 389–392 (1991)

    Article  Google Scholar 

  8. Egeland, G.M., Matthews, K.A., Kuller, L.H., Kelsey, S.: Characteristics of noncontraceptive hormone users. Preventive Medicine 17(4), 403–411 (1988)

    Article  Google Scholar 

  9. Sobal, J., Stunkard, A.J.: Socioeconomic status and obesity: a review of the literature. Psychological Bulletin 105(2), 260–275 (1989)

    Article  Google Scholar 

  10. Moser, K., Patnick, J., Beral, V.: Inequalities in reported use of breast and cervical screening in Great Britain: Analysis of cross sectional survey data. British Medical Journal 338, b. 2025 (2009)

    Google Scholar 

  11. Vachon, C.M., Kuni, C.C., Anderson, K., Anderson, V.E., Sellers, T.A.: Association of mammographically defined percent breast density with epidemiologic risk factors for breast cancer (United States). Cancer Causes & Control 11(7), 653–662 (2000)

    Article  Google Scholar 

  12. Aitken, Z., Walker, K., Stegeman, B., Wark, P., Moss, S., McCormack, V., et al.: Mammographic density and markers of socioeconomic status: a cross-sectional study. BMC Cancer 10(1), 35 (2010)

    Article  Google Scholar 

  13. Evans, G.: PROCAS study (2011), http://www.uhsm.nhs.uk/research/Pages/PROCASstudy.aspx (June 16, 2013)

  14. Hologic- Quantra Volumetric Assessment (2012), http://www.hologic.com/en/breast-screening/volumetric-assessment/

  15. Volpara Density (2013), http://www.volparadensity.com/

  16. Department for Communities and Local Government. English indices of deprivation. Online: GOV.UK (2012), https://www.gov.uk/government/organisations/department-for-communities-and-local-government/series/english-indices-of-deprivation (cited June 02, 2013)

  17. Sauber, N., Chan, A., Highnam, R.: BI-RADS breast density classification - an international standard? In: EPOS, European Society of Radiology, Online: European Society of Radiology (2013)

    Google Scholar 

  18. Gross, C.P., Filardo, G., Mayne, S.T., Krumholz, H.M.: The impact of socioeconomic status and race on trial participation for older women with breast cancer. Cancer 103(3), 483–491 (2005)

    Article  Google Scholar 

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Authors and Affiliations

  1. Manchester Medical School, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, UK

    Louisa Samuels & D. Gareth Evans

  2. Centre for Imaging Sciences, Institute of Population Health, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, UK

    Elaine Harkness, Susan M. Astley, Anthony Maxwell & Jamie Sergeant

  3. Genesis Breast Cancer Prevention Centre, University Hospital of South Manchester NHS Trust, Wythenshawe, Manchester, M23 9LT, UK

    Elaine Harkness, Susan M. Astley, Anthony Maxwell, Mary Wilson, Paula Stavrinos, D. Gareth Evans, Tony Howell & Megan Bydder

  4. Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, The University of Manchester, Wythenshawe, Manchester, M23 9LT, UK

    Elaine Harkness, Susan M. Astley, Anthony Maxwell, Julie Morris, Paula Stavrinos, D. Gareth Evans & Tony Howell

  5. Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK

    Jamie Sergeant

  6. NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, UK

    Jamie Sergeant

  7. Centre for Biostatistics, Institute of Population Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK

    Julie Morris

  8. Manchester Centre for Genomic Medicine, Central Manchester Foundation Trust, St. Mary’s Hospital, Oxford Road, Manchester, M13 9WL, UK

    D. Gareth Evans

  9. Manchester Breast Centre, Manchester Cancer Research Centre, University of Manchester, Christie Hospital, Withington, Manchester, M20 4BX, UK

    Susan M. Astley, Anthony Maxwell & Tony Howell

Authors
  1. Louisa Samuels
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  2. Elaine Harkness
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  3. Susan M. Astley
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  4. Anthony Maxwell
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  5. Jamie Sergeant
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  6. Julie Morris
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  7. Mary Wilson
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  8. Paula Stavrinos
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  9. D. Gareth Evans
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  10. Tony Howell
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  11. Megan Bydder
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Editors and Affiliations

  1. Department of Intelligent Image Information, Gifu University Graduate School of Medicine, 1-1 Yanagido, 501-1194, Gifu, Gifu, Japan

    Hiroshi Fujita , Takeshi Hara  & Chisako Muramatsu ,  & 

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Samuels, L. et al. (2014). The Relationship of Volumetric Breast Density to Socio-Economic Status in a Screening Population. In: Fujita, H., Hara, T., Muramatsu, C. (eds) Breast Imaging. IWDM 2014. Lecture Notes in Computer Science, vol 8539. Springer, Cham. https://doi.org/10.1007/978-3-319-07887-8_39

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  • DOI: https://doi.org/10.1007/978-3-319-07887-8_39

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-07886-1

  • Online ISBN: 978-3-319-07887-8

  • eBook Packages: Computer ScienceComputer Science (R0)

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