Abstract
A new imaging system based on an x-ray Talbot-Lau interferometry was developed. The preclinical study with mastectomy specimens was conducted, and the three types of images, i.e., the attenuation contrast(ATT) image, the differential phase contrast(DPC) image, and the x-ray small angle scattering(SAS) image, obtained by the system were compared to the pathological result. As a result, the SAS image showed micro-calcifications clearly. On the other hand, the inside of the mass with invasive carcinoma was visualized with relatively lower signal. The SAS image seemed to correspond to the homogeneity of the breast tissues. The breast images obtained with Talbot-Lau interferometry showed the different aspects which cannot be depicted with the conventional x-ray image. Comparative reading of the three images would enable us to get additional information of breast tissues.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Momose, A., Kawamoto, S., Koyama, I., Hamaishi, Y., Takai, K., Suzuki, Y.: Demonstration of X-ray Talbot Interferometry. Jpn J. Appl. Phys. 42, L866-L868 (2003)
Pfeiffer, F., Weitkamp, T., Bunk, O., David, C.: Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources. Nat. Phys. 2, 258–261 (2006)
Stampanoni, M., Wang, Z., Thuring, T., David, C., Roessl, E., Trippel, M., Kubik-Huch, R.A., Singer, G., Hohl, M.K., Hauser, N.: The First Analysis and Clinical Evaluation of Native Breast Tissue Using Differential Phase-Contrast Mammography. Invest. Radiol. 46, 801–806 (2011)
Anton, G., Bayer, F., Beckmann, M.W., Durst, J., Fasching, P.A., Haas, W., Hartmann, A., Michel, T., Pelzer, G., Radicke, M., Rauh, C., Rieger, J., Ritter, A., Schulz-Wendtland, R., Uder, M., Wachter, D.L., Weber, T., Wenkel, E., Wucherer, L.: Grating-based darkfield imaging of human breast tissue. Z. Med. Phys. 23, 228–235 (2013)
Endo, T., Ooiwa, M., Shiraiwa, M., Morita, T., Ichihara, S., Moritani, S., Hasegawa, M., Satoh, Y., Hayashi, T., Katou, A., Kiyohara, J., Nagatsuka, S., Momose, A.: Development of a New Breast Imaging Method Based on X-ray Talbot-Lau Interferometry. In: RSNA 2011 SSC15 (2011)
Noda, D., Tanaka, M., Shimada, K., Hattori, T.: Fabrication of Diffraction Grating with High Aspect Ratio Using X-ray Lithography Technique for X-ray Phase Imaging. Jpn J. Appl. Phys. 46, 849–851 (2007)
Pfeiffer, F., Bech, M., Bunk, O., Kraft, P., Eikenberry, E.F., Bronnimann, C., Grunzweig, C., David, C.: Hard X-ray dark-field imaging using a grating interferometer. Nat. Mater. 7, 134–137 (2008)
Tanaka, J., Nagashima, M., Kido, K., Hoshino, Y., Kiyohara, J., Makifuchi, C., Nishino, S., Nagatsuka, S., Momose, A.: Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry. Z. Med. Phys. 23, 222–227 (2013)
Yashiro, W., Terui, Y., Kawabata, K., Momose, A.: On the origin of visibility contrast in x-ray Talbot interferometry. Opt. Express 18, 16890–16901 (2010)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer International Publishing Switzerland
About this paper
Cite this paper
Endo, T. et al. (2014). Development of New Imaging System Based on Grating Interferometry : Preclinical Study in Breast Imaging. In: Fujita, H., Hara, T., Muramatsu, C. (eds) Breast Imaging. IWDM 2014. Lecture Notes in Computer Science, vol 8539. Springer, Cham. https://doi.org/10.1007/978-3-319-07887-8_68
Download citation
DOI: https://doi.org/10.1007/978-3-319-07887-8_68
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-07886-1
Online ISBN: 978-3-319-07887-8
eBook Packages: Computer ScienceComputer Science (R0)