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A Simulation for Proportional Biological Operational Mu-Circuit

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Bioinformatics Research and Applications (ISBRA 2014)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 8492))

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Abstract

To quantitatively control the expression of target gene is challenging but highly desired in practice. We design a device-Biological Proportional Operational Mu-circuit (P-BOM) incorporating AND/OR gate and operational amplifier into one circuit and explore its behaviors through simulation. The results imply that we can control input-output proportionly by manipulating the RBS of hrpR, hrpS, tetR and output gene.

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Author information

Authors and Affiliations

  1. Harbin Institute of Technology, Harbin, China

    Dechang Xu, Ke Liu, Xiangmiao Zeng, Yujing Ouyang, Cuihong Dai, Aiju Hou, Dayou Cheng & Jianzhong Li

  2. Georgia State University, Atlanta, USA

    Zhipeng Cai

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  1. Dechang Xu
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  2. Zhipeng Cai
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  3. Ke Liu
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  4. Xiangmiao Zeng
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  5. Yujing Ouyang
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  6. Cuihong Dai
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  7. Aiju Hou
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  8. Dayou Cheng
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  9. Jianzhong Li
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Editor information

Editors and Affiliations

  1. Johns Hopkins University, Computer Science Department, Baltimore, MD 21218, USA and National Science Foundation, 1115, CCF, USA

    Mitra Basu

  2. Department of Computer Science, Georgia State University, 30303, Atlanta, GA, USA

    Yi Pan

  3. School of Information Science and Engineering, Central South University, 410083, Changsha, China

    Jianxin Wang

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© 2014 Springer International Publishing Switzerland

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Xu, D. et al. (2014). A Simulation for Proportional Biological Operational Mu-Circuit . In: Basu, M., Pan, Y., Wang, J. (eds) Bioinformatics Research and Applications. ISBRA 2014. Lecture Notes in Computer Science(), vol 8492. Springer, Cham. https://doi.org/10.1007/978-3-319-08171-7_8

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  • DOI: https://doi.org/10.1007/978-3-319-08171-7_8

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-08170-0

  • Online ISBN: 978-3-319-08171-7

  • eBook Packages: Computer ScienceComputer Science (R0)

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