Abstract
Identification of differentially expressed genes between two sample groups are important to find which genes are increased in expression (up-regulated) or decreased in expression (down-regulated). We have identified differentially expressed genes between wild type HIV-1 Vpr and two HIV-1 mutant Vprs separately by using statistical t-test and false discovery rate. We also compute q-value of test to measure minimum FDR which occurs. We have found 1524 number of differentially expressed genes between wild type HIV-1 vpr and HIV-1 mutant vpr, R80A. Again we found 1525 diffrential genes between wild type HIV-1 vpr and HIV-1 mutant vpr, F72A/R73A. From these two differentially expressed gene sets we get 941 number of down-regulated genes for both sets and rest genes are found as up-regulated genes.
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Barman, B., Mukhopadhyay, A. (2015). Detection of Differentially Expressed Genes in Wild Type HIV-1 Vpr and Two HIV-1 Mutant Vprs. In: Satapathy, S., Biswal, B., Udgata, S., Mandal, J. (eds) Proceedings of the 3rd International Conference on Frontiers of Intelligent Computing: Theory and Applications (FICTA) 2014. Advances in Intelligent Systems and Computing, vol 327. Springer, Cham. https://doi.org/10.1007/978-3-319-11933-5_67
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DOI: https://doi.org/10.1007/978-3-319-11933-5_67
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-11932-8
Online ISBN: 978-3-319-11933-5
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