Skip to main content

Supporting Bioinformatics Applications with Hybrid Multi-cloud Services

  • Conference paper
Bioinformatics and Biomedical Engineering (IWBBIO 2015)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 9043))

Included in the following conference series:

Abstract

Cloud computing provides a promising solution to the big data problem associated with next generation sequencing applications. The increasing number of cloud service providers, who compete in terms of performance and price, is a clear indication of a growing market with high demand. However, current cloud computing based applications in bioinformatics do not profit from this progress, because they are still limited to just one cloud service provider. In this paper, we present different use case scenarios using hybrid services and resources from multiple cloud providers for bioinformatics applications. We also present a new version of the elasticHPC package to realize these scenarios and to support the creation of cloud computing resources over multiple cloud platforms, including Amazon, Google, Azure, and clouds supporting OpenStack. The instances created on these cloud environments are pre-configured to run big sequence analysis tasks using a large set of pre-installed software tools and parallelization techniques. In addition to its flexibility, we show by experiments that the use of hybrid cloud resources from different providers can save time and cost.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Angiuoli, S., Matalka, M., Gussman, A., et al.: CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computing. BMC Bioinformatics 12(1), 356+ (2011)

    Google Scholar 

  2. Gregory, J., Kuczynski, J., Stombaugh, J.: QIIME allows analysis of high-throughput community sequencing data. Nat. Meth. 7(5), 335–336 (2010)

    Article  Google Scholar 

  3. Langmead, B., Schatz, M.C., Lin, J., Pop, M., Salzberg, S.L.: Searching for snps with cloud computing. Genome Biology 10(R134) (2009)

    Google Scholar 

  4. Wall, D.P., Kudtarkar, P., Fusaro, V.A., Pivovarov, R., Patil, P., Tonellato, P.J.: Cloud computing for comparative genomics. BMC Bioinformatics 11, 259 (2010)

    Article  Google Scholar 

  5. Langmead, B., Hansen, K., Leek, J.: Cloud-scale rna-sequencing differential expression analysis with Myrna. Genome Biology 11(8), R83+ (2010)

    Google Scholar 

  6. StarCluster, http://web.mit.edu/stardev/cluster

  7. Vappio, http://vappio.sf.net

  8. Afgan, E., Coraor, N., Chapman, B., et al.: Galaxy CloudMan: delivering cloud compute clusters. BMC Bioinformatics 11(suppl. 12), S4+ (2010)

    Google Scholar 

  9. El-Kalioby, M., Abouelhoda, M., Krüger, J., et al.: Personalized cloud-based bioinformatics services for research and education: use cases and the elastichpc package. BMC Bioinformatics 13(S-17), S22 (2012)

    Google Scholar 

  10. AWS: Amazon Web Services, http://aws.amazon.com

  11. Azure, W., http://www.microsoft.com/windowsazure

  12. Magellan-a cloud for Science, http://magellan.alcf.anl.gov

  13. DIAG-Data Intensive Academic Grid, http://diagcomputing.org

  14. Li, H., Durbin, R.: Fast and accurate short read alignment with burrows and wheeler transform. Bioinformatics 25(14), 1754–1760 (2009)

    Article  Google Scholar 

  15. DePristo, M., Banks, E., et al.: A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nature Genetics 43(5), 491–498 (2011)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this paper

Cite this paper

Ali, A.A., El-Kalioby, M., Abouelhoda, M. (2015). Supporting Bioinformatics Applications with Hybrid Multi-cloud Services. In: Ortuño, F., Rojas, I. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2015. Lecture Notes in Computer Science(), vol 9043. Springer, Cham. https://doi.org/10.1007/978-3-319-16483-0_41

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-16483-0_41

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-16482-3

  • Online ISBN: 978-3-319-16483-0

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics