Abstract
Cardiovascular disease (CVD) is one of the key causes for death worldwide. We consider the problem of modeling an imaging biomarker, Coronary Artery Calcification (CAC) measured by computed tomography, based on behavioral data. We employ the formalism of Dynamic Bayesian Network (DBN) and learn a DBN from these data. Our learned DBN provides insights about the associations of specific risk factors with CAC levels. Exhaustive empirical results demonstrate that the proposed learning method yields reasonable performance during cross-validation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Detrano, R., Guerci, A.D., Carr, J.J., et al.: Coronary calcium as a predictor of coronary events in four racial or ethnic groups. New England Journal of Medicine 358(13), 1336–1345 (2008)
Eaton, D., Murphy, K.: Bayesian structure learning using dynamic programming and MCMC. In: UAI (2007)
Koller, D., Friedman, N.: Probabilistic Graphical Models: Principles and Techniques. MIT Press (2009)
Liu, Z., Malone, B.M., Yuan, C.: Empirical evaluation of scoring functions for bayesian network model selection. BMC Bioinformatics 13(S-15), S14 (2012)
Vinh, N.X., Chetty, M., Coppel, R.L., et al.: Globalmit: learning globally optimal dynamic bayesian network with the mutual information test criterion. Bioinformatics 27(19), 2765–2766 (2011)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Yang, S., Kersting, K., Terry, G., Carr, J., Natarajan, S. (2015). Modeling Coronary Artery Calcification Levels from Behavioral Data in a Clinical Study. In: Holmes, J., Bellazzi, R., Sacchi, L., Peek, N. (eds) Artificial Intelligence in Medicine. AIME 2015. Lecture Notes in Computer Science(), vol 9105. Springer, Cham. https://doi.org/10.1007/978-3-319-19551-3_24
Download citation
DOI: https://doi.org/10.1007/978-3-319-19551-3_24
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-19550-6
Online ISBN: 978-3-319-19551-3
eBook Packages: Computer ScienceComputer Science (R0)