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Simulating the Effect of Cell Migration Speed on Wound Healing Using a 3D Cellular Automata Model for Multicellular Tissue Growth

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Computational Science and Its Applications -- ICCSA 2015 (ICCSA 2015)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 9156))

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Abstract

We present the simulation of the effect of cell migration speed on wound healing using a three-dimensional computational model for multicellular tissue growth. The computational model uses a discrete approach based on cellular automata to simulate wound-healing times and tissue growth rates of multiple populations of proliferating and migrating cells. Each population of cells has its own division, motion, collision, and aggregation characteristics resulting in a number of useful system parameters that allow us to investigate their emergent effects. Our sequential performance results point to the need of porting the model to modern high performance machines to harness the computational power available in multicore and GPU-based computers. Discrete systems of this kind can be a valuable approach for studying many complex systems, including biological ones.

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Authors and Affiliations

  1. Department of Computer Engineering, College of Computer and Information Sciences, King Saud University, Riyadh, Saudi Arabia

    Belgacem Ben Youssef

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  1. Belgacem Ben Youssef
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Correspondence to Belgacem Ben Youssef .

Editor information

Editors and Affiliations

  1. University of Perugia, Perugia, Italy

    Osvaldo Gervasi

  2. University of Basilicata, Potenza, Italy

    Beniamino Murgante

  3. Covenant University, Canaanland, Nigeria

    Sanjay Misra

  4. University of Calgary, Calgary, Alberta, Canada

    Marina L. Gavrilova

  5. University of Minho, Braga, Portugal

    Ana Maria Alves Coutinho Rocha

  6. Polytechnic University, Bari, Italy

    Carmelo Torre

  7. Monash University, Clayton, Victoria, Australia

    David Taniar

  8. Kyushu Sangyo University, Fukuoka, Japan

    Bernady O. Apduhan

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Ben Youssef, B. (2015). Simulating the Effect of Cell Migration Speed on Wound Healing Using a 3D Cellular Automata Model for Multicellular Tissue Growth. In: Gervasi, O., et al. Computational Science and Its Applications -- ICCSA 2015. ICCSA 2015. Lecture Notes in Computer Science(), vol 9156. Springer, Cham. https://doi.org/10.1007/978-3-319-21407-8_3

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  • DOI: https://doi.org/10.1007/978-3-319-21407-8_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21406-1

  • Online ISBN: 978-3-319-21407-8

  • eBook Packages: Computer ScienceComputer Science (R0)

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