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PARA-Antibodies: An Immunological Model for Clonal Expansion Based on Bacteriophages and Plasmids

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Advances in Nature and Biologically Inspired Computing

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 419))

Abstract

This paper presents a novel method for modelling the growth of agents undergoing clonal expansion. Using the concept of plasmids, clonal agents are broken into components which can be judged independently of the agents themselves. These components can be redistributed by objects analogous to bacteriophages. Full algorithms for the model are given, and results of an implementation provided. The work presented in this paper has significant implications for the field of clonal expansion.

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References

  1. Biology-Online: Plasmid http://www.biology-online.orgidictionary/Plasmid (2009). Accessed 4 April 2012

  2. Cavanagh, J.P., Hjerde, E., Holden, M.T., Kahlke, T., Klingenberg, C., Flægstad, T., Parkhill, J., Bentley, S.D., Sollid, J.U.E.: Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals. J. Antimicrob. Chemother. 69(11), 2920–2927 (2014)

    Article  Google Scholar 

  3. Dasgupta, D., Niño, L.F.: Immunological Computation—Theory and Application. Auerbach Publications, Boca Raton (2009)

    Google Scholar 

  4. Hartl, D.L., Jones, E.W.: Genetics: Principles and Analysis (1998)

    Google Scholar 

  5. Maloy, S.: Horizontal gene transfer, http://www.sci.sdsu.edu/smaloy/MicrobialGenetics/topicsigenetic-exchange/exchange/exchange.html (2002). Accessed 4 April 2012

  6. Monteiro, S.M., Goldberg, E.F., Goldberg, M.C.: A plasmid based transgenetic algorithm for the biobjective minimum spanning tree problem, pp. 49–60 (2009)

    Google Scholar 

  7. Rocha, D.A.M., Goldberg, E.F.G., Goldberg, M.C.: A new evolutionary algorithm for the biobjective minimum spanning tree, pp. 735–740 (2007)

    Google Scholar 

  8. Soucy, S.M., Huang, J., Gogarten, J.P.: Horizontal gene transfer: building the web of life. Nat, Rev. Genet. 16(8), 472–482 (2015)

    Article  Google Scholar 

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Authors and Affiliations

  1. Academy of Computer Science and Software Engineering, University of Johannesburg, Johannesburg, South Africa

    Mark Heydenrych & Elizabeth Marie Ehlers

Authors
  1. Mark Heydenrych
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  2. Elizabeth Marie Ehlers
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Corresponding author

Correspondence to Mark Heydenrych .

Editor information

Editors and Affiliations

  1. School of Mathematics, Statistics and CS, University of KwaZulu-Natal, Pietermaritzburg, South Africa

    Nelishia Pillay

  2. Sch of IT, Dept of CS, University of Pretoria, Pretoria, South Africa

    Andries P. Engelbrecht

  3. Sci N/w for Innova and Research Exc, Machine Intelligence Research Labs, Auburn, Washington, USA

    Ajith Abraham

  4. Department of Computing Sciences,, Nelson Mandela Metropolitan University, Port Elizabeth, South Africa

    Mathys C. du Plessis

  5. Faculty of Electrical Engineering and, Technical University of Ostrava, Ostrava-Poruba, Czech Republic

    Václav Snášel

  6. Fakulti Teknologi Maklumat dan Komunikas, Universiti Teknikal Malaysia Melaka, Durian Tunggal, Malaysia

    Azah Kamilah Muda

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Heydenrych, M., Ehlers, E.M. (2016). PARA-Antibodies: An Immunological Model for Clonal Expansion Based on Bacteriophages and Plasmids. In: Pillay, N., Engelbrecht, A., Abraham, A., du Plessis, M., Snášel, V., Muda, A. (eds) Advances in Nature and Biologically Inspired Computing. Advances in Intelligent Systems and Computing, vol 419. Springer, Cham. https://doi.org/10.1007/978-3-319-27400-3_16

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  • DOI: https://doi.org/10.1007/978-3-319-27400-3_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-27399-0

  • Online ISBN: 978-3-319-27400-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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