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ISLES Challenge 2015: Automated Model-Based Segmentation of Ischemic Stroke in MR Images

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Book cover Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (BrainLes 2015)

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Abstract

We present a novel fully-automated generative ischemic stroke lesion segmentation method that can be applied to individual patient images without need for a training data set. An Expectation Maximization-approach is used for estimating intensity models for both normal and pathological tissue. The segmentation is represented by a level-set that is iteratively updated to label voxels as either normal or pathological, based on which intensity model explains the voxels’ intensity the best. A convex level-set formulation is adopted, that eliminates the need for manual initialization of the level-set. The performance of the method for segmenting the ischemic stroke is summarized by an average Dice score of \(0.78\pm 0.08\) and \(0.53 \pm 0.26\) for the SPES and SISS 2015 training data set respectively and \(0.67\pm 0.24\) and \(0.37 \pm 0.33\) for the test data set.

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References

  1. Rekik, I., Allassonnière, S., Carpenter, T.K., Wardlaw, J.M.: Medical image analysis methods in MR/CT-imaged acute-subacute ischemic stroke lesion: segmentation, prediction and insights into dynamic evolution simulation models. A critical appraisal. NeuroImage Clin. 1(1), 164–178 (2012)

    Article  Google Scholar 

  2. Van Leemput, K., Maes, F., Vandermeulen, D., Suetens, P.: Automated model-based tissue classification of MR images of the brain. IEEE Trans. Med. Imaging 18, 897–908 (1999)

    Article  Google Scholar 

  3. Rousson, M., Deriche, R.: A variational framework for active and adaptative segmentation of vector valued images. In: Proceedings of the Workshop on Motion and Video Computing, MOTION 2002. IEEE Computer Society (2002)

    Google Scholar 

  4. Riklin-Raviv, T., Van Leemput, K., Menze, B.H., Wells, W.M., Golland, P.: Segmentation of image ensembles via latent atlases. Med. Image Anal. 14(5), 654–665 (2010)

    Article  Google Scholar 

  5. Chan, T.F., Esedoglu, S., Nikolova, M.: Algorithms for finding global minimizers of image segmentation and denoising models. SIAM J. Appl. Math. 66(5), 1632–1648 (2006)

    Article  MathSciNet  MATH  Google Scholar 

  6. Goldstein, T., Bresson, X., Osher, S.: Geometric applications of the split Bregman method: segmentation and surface reconstruction. J. Sci. Comput. 45(1–3), 272–293 (2010)

    Article  MathSciNet  MATH  Google Scholar 

  7. Avants, B.B., Tustison, N.J., Song, G., Cook, P.A., Klein, A., Gee, J.C.: A reproducible evaluation of ants similarity metric performance in brain image registration. Neuroimage 54(3), 2033–2044 (2011)

    Article  Google Scholar 

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Correspondence to Tom Haeck .

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Haeck, T., Maes, F., Suetens, P. (2016). ISLES Challenge 2015: Automated Model-Based Segmentation of Ischemic Stroke in MR Images. In: Crimi, A., Menze, B., Maier, O., Reyes, M., Handels, H. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2015. Lecture Notes in Computer Science(), vol 9556. Springer, Cham. https://doi.org/10.1007/978-3-319-30858-6_21

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  • DOI: https://doi.org/10.1007/978-3-319-30858-6_21

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-30857-9

  • Online ISBN: 978-3-319-30858-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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