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An Expert-in-the-loop Paradigm for Learning Medical Image Grouping

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Advances in Knowledge Discovery and Data Mining (PAKDD 2016)

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Abstract

Image grouping in knowledge-rich domains is challenging, since domain knowledge and expertise are key to transform image pixels into meaningful content. Manually marking and annotating images is not only labor-intensive but also ineffective. Furthermore, most traditional machine learning approaches cannot bridge this gap for the absence of experts’ input. We thus present an interactive machine learning paradigm that allows experts to become an integral part of the learning process. This paradigm is designed for automatically computing and quantifying interpretable grouping of dermatological images. In this way, the computational evolution of an image grouping model, its visualization, and expert interactions form a loop to improve image grouping. In our paradigm, dermatologists encode their domain knowledge about the medical images by grouping a small subset of images via a carefully designed interface. Our learning algorithm automatically incorporates these manually specified connections as constraints for re-organizing the whole image dataset. Performance evaluation shows that this paradigm effectively improves image grouping based on expert knowledge.

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Notes

  1. 1.

    Primary morphology terms (PRI) and 8 other categories of terms were identified by 2 highly trained dermatologists as thought units in an annotation study to label the stages in diagnostic reasoning [17]. Used here in this interface, these thought units can disclose the influence of each category of terms on the medical image grouping.

  2. 2.

    We do not define image similarity for domain experts to not restrict them by layperson definitions. We use t-SNE only as a feature projection technique for low dimensional visualization.

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Acknowledgments

This work was partially supported by NIH grant 1R21 LM010039-01A1 and NSF grant IIS-0941452. We would like to thank the participating physicians, the reviewers; and Logical Images, Inc. for images. Any opinions, findings, and conclusions or recommendations expressed in this paper are those of the authors and do not necessarily reflect the official views of the NIH or the NSF.

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Correspondence to Xuan Guo .

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Guo, X. et al. (2016). An Expert-in-the-loop Paradigm for Learning Medical Image Grouping. In: Bailey, J., Khan, L., Washio, T., Dobbie, G., Huang, J., Wang, R. (eds) Advances in Knowledge Discovery and Data Mining. PAKDD 2016. Lecture Notes in Computer Science(), vol 9651. Springer, Cham. https://doi.org/10.1007/978-3-319-31753-3_38

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  • DOI: https://doi.org/10.1007/978-3-319-31753-3_38

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