Abstract
In this paper, we introduce the new software environment CRIMSON: CardiovasculaR Integrated Modelling and SimulatiON. This software provides a number of tools for medical image data analysis, preprocessing, segmentation and blood flow simulation. In this paper we describe the work flow necessary to perform such tasks as well its implementation in CRIMSON based on multiple well-established open-source libraries, such as MITK and OpenCASCADE. We show that the software is easy to use for both experts and non-experts in the field of hemodynamic modelling. The intuitive and responsive interface of CRIMSON facilitates learning and speeds up the model building process by up to a factor of two compared to the existing tool being used for the same purpose. The overall goal of this work is to produce a feature-rich and intuitive open-source blood flow modelling framework that can be used both by engineers and medical personnel.
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Additional information can be found at http://www.crimson.software.
References
Bloomenthal, J.: Calculation of Reference Frames Along a Space Curve. In: Graphics Gems, pp. 567–571. Academic Press Prof. Inc, San Diego, CA (1990)
Herman, G.T., Zheng, J., Bucholtz, C.A.: Shape-based interpolation. IEEE Comput. Graph. Appl. 12(3), 69–79 (1992)
Kretschmer, J., Godenschwager, C., Preim, B., Stamminger, M.: Interactive patient-specific vascular modeling with sweep surfaces. IEEE Trans. Vis. Comput. Graphics 19(12), 2828–2837 (2013)
Mazzeo, M., Coveney, P.: HemeLB: a high performance parallel lattice-Boltzmann code for large scale fluid flow in complex geometries. Comput. Phys. Commun. 178(12), 894–914 (2008)
Noorani, A., Kiessewetter, C., Botnar, R., Figueroa, C.A., Henningsson, M.: Volumetric black-blood imaging of aortic dissection using t2 prepared inversion recovery. J. Cardiovasc. Magn. Reson. 17(Suppl 1), 396 (2015)
Schmidt, J., Delp, S., Sherman, M., Taylor, C., Pande, V., Altman, R.: The simbios national center: systems biology in motion. Proc. IEEE 96(8), 1266–1280 (2008)
Schneider, P.J., Eberly, D.: Geometric Tools for Computer Graphics. Elsevier Science Inc., New York (2002)
Wang, K., Dutton, R.: Improving geometric model construction for blood flow modeling. IEEE Eng. Med. Biol. Mag. 18(6), 33–39 (1999). IEEE
Wolf, I., Vetter, M., Wegner, I., Bttger, T., Nolden, M., Schbinger, M., Hastenteufel, M., Kunert, T., Meinzer, H.P.: The medical imaging interaction toolkit. Med. Image Anal. 9(6), 594–604 (2005)
Acknowledgement
We gratefully acknowledge support from the ERC under the EUs 7th Framework Programme / ERC Grant Agreement n. 307532, and the UK Department of Health via the NIHR comprehensive Biomedical Research Centre award to Guys and St Thomas NHS Foundation Trust in partnership with KCL and Kings College Hospital NHS Foundation Trust.
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Khlebnikov, R., Figueroa, C.A. (2016). CRIMSON: Towards a Software Environment for Patient-Specific Blood Flow Simulation for Diagnosis and Treatment. In: Oyarzun Laura, C., et al. Clinical Image-Based Procedures. Translational Research in Medical Imaging. CLIP 2015. Lecture Notes in Computer Science(), vol 9401. Springer, Cham. https://doi.org/10.1007/978-3-319-31808-0_2
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DOI: https://doi.org/10.1007/978-3-319-31808-0_2
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