Abstract
Fractional flow reserve (FFR) is the golden standard for making decision on surgical treatment of coronary vessels with multiple stenosis. Clinical measurements of FFR require expensive invasive procedure with endovascular ultrasound probe. In this work a method of FFR simulation is considered. It is based on modelling 1D haemodynamics in patient-specific coronary vessels network reconstructed from CT scans. In contrast to our previous studies we used explicit minimum oscillating 2nd order characteristic method for internal nodes and 2nd order approximation of compatibility conditions for discretization of boundary conditions in junctions. The model is applied for simulating the change of FFR due to variability of the vessels elasticity and autoregulation response rate.
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Acknowledgements
The research was supported by Russian Science Foundation (RSF) grant 14-31-00024.
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Gamilov, T., Kopylov, P., Simakov, S. (2016). Computational Simulations of Fractional Flow Reserve Variability. In: Karasözen, B., Manguoğlu, M., Tezer-Sezgin, M., Göktepe, S., Uğur, Ö. (eds) Numerical Mathematics and Advanced Applications ENUMATH 2015. Lecture Notes in Computational Science and Engineering, vol 112. Springer, Cham. https://doi.org/10.1007/978-3-319-39929-4_48
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DOI: https://doi.org/10.1007/978-3-319-39929-4_48
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