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Automatic Whole-Heart Segmentation in Congenital Heart Disease Using Deeply-Supervised 3D FCN

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Reconstruction, Segmentation, and Analysis of Medical Images (RAMBO 2016, HVSMR 2016)

Abstract

Accurate whole-heart segmentation plays an important role in the surgical planning for heart defects such as congenital heart disease (CHD). In this work, we propose a deep learning method for automatic whole-heart segmentation in cardiac magnetic resonance (CMR) images with CHD. First, we start with a 3D fully convolutional network (3D FCN) in order to ensure an efficient voxel-wise labeling. Then we introduce dilated convolutional layers (3D-HOL layers) into the baseline model to expand its receptive field, so as to make better use of the spatial information. Last, we employ deeply-supervised pathways to accelerate training and exploit multi-scale information. We evaluate the proposed method on 3D CMR images from the dataset of the HVSMR 2016 Challenge. The results of controlled experiments demonstrate the efficacy of the proposed 3D-HOL layers and deeply-supervised pathways. We achieve an average Dice score of 80.1% in training (5-fold cross-validation) and 69.5% in testing.

J. Li and R. Zhang—Joint first authors.

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Notes

  1. 1.

    Other combination operators such as summation or max fusion need more memory to store the new volumes, whereas by concatenation we can directly do the processing on the existed volumes.

  2. 2.

    http://segchd.csail.mit.edu/data.html.

  3. 3.

    During the training phase, we noticed that the time point at which the loss of the 3D-FCN-HOL network started to decrease was later than the baseline’s, and the descent speed was also lower, which indicates that the network with 3D-HOL layers is more difficult to train.

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Acknowledgements

The work described in this paper was partially supported by a grant from the Science, Technology and Innovation Commission of Shenzhen Municipality (No.: CXZZ20140606164105361), a grant from Technology and Business Development Fund (No.: TBF15MED004), a grant from the Innovation and Technology Commission (No.: ITS/293/14FP), and grants from the Research Grants Council of the Hong Kong Special Administrative Region, China (No.: CUHK 416712, and CUHK 14113214), and a grant from the National Natural Science Foundation of China (No.: 81271653).

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Correspondence to Defeng Wang .

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Li, J., Zhang, R., Shi, L., Wang, D. (2017). Automatic Whole-Heart Segmentation in Congenital Heart Disease Using Deeply-Supervised 3D FCN. In: Zuluaga, M., Bhatia, K., Kainz, B., Moghari, M., Pace, D. (eds) Reconstruction, Segmentation, and Analysis of Medical Images. RAMBO HVSMR 2016 2016. Lecture Notes in Computer Science(), vol 10129. Springer, Cham. https://doi.org/10.1007/978-3-319-52280-7_11

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  • DOI: https://doi.org/10.1007/978-3-319-52280-7_11

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