Abstract
Evaluating disease progression risk is a key issue in medicine that has been revolutionized by the advent of machine learning approaches and the wide availability of medical data in electronic form. It is time to provide physicians with near-to-the-clinical-practice and effective tools to spread this important technological innovation. In this paper, we describe RISK, a web service that implements a multiple kernel learning approach for predicting breast cancer disease progression. We report on the experience of the BIBIOFAR project where RISK Web Predictor has been developed and tested. Results of our system demonstrate that this kind of approaches can effectively support physicians in the evaluation of risk.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Delen, D., Walker, G., Kadam, A.: Predicting breast cancer survivability: a comparison of three data mining methods. Artif. Intell. Med. 34(2), 113–127 (2005)
Sun, Y., Goodison, S., Li, J., Liu, L., Farmerie, W.: Improved breast cancer prognosis through the combination of clinical and genetic markers. Bioinformatics 23(1), 30–37 (2007)
Kim, J., Shin, H.: Breast cancer survivability prediction using labeled, unlabeled, and pseudo-labeled patient data. J. Am. Med. Inform. Assoc. 20(4), 613–618 (2013)
Park, K., Ali, A., Kim, D., An, Y., Kim, M., Shin, H.: Robust predictive model for evaluating breast cancer survivability. Eng. Appl. Artif. Intell. 26(9), 2194–2205 (2013)
Ferroni, P., et al.: Risk assessment for venous thromboembolism in chemotherapy-treated ambulatory cancer patients: a machine learning approach. Med. Decis. Mak. 37(2), 234–242 (2016)
Cristianini, N., Shawe-Taylor, J.: An introduction to support vector machines and other kernel based learning methods. Ai Mag. 22(2), 190 (2000)
Matyas, J.: Random optimization. Autom. Remote Control 26(2), 246–253 (1965)
Ferroni, P., et al.: Pretreatment insulin levels as a prognostic factor for breast cancer progression. Oncologist 21(9), 1041–1049 (2016)
Filice, S., Croce, D., Basili, R., Zanzotto, F.M.: Linear online learning over structured data with distributed tree kernels. In: Proceedings of the 2013 12th International Conference on Machine Learning and Applications, ICMLA 2013, vol. 1, pp. 123–128 (2013)
Filice, S., Castellucci, G., Croce, D., Basili, R.: KeLP: a kernel-based learning platform for natural language processing. In: Proceedings of ACL-IJCNLP 2015 System Demonstrations (2015)
Acknowledgements
This work was partially supported by the European Social Fund, under the Italian Ministry of Education, University and Research PON03PE_00146_1/10 BIBIOFAR (CUP B88F12000730005) to Guadagni F.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this paper
Cite this paper
Guadagni, F. et al. (2017). RISK: A Random Optimization Interactive System Based on Kernel Learning for Predicting Breast Cancer Disease Progression. In: Rojas, I., Ortuño, F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2017. Lecture Notes in Computer Science(), vol 10208. Springer, Cham. https://doi.org/10.1007/978-3-319-56148-6_16
Download citation
DOI: https://doi.org/10.1007/978-3-319-56148-6_16
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-56147-9
Online ISBN: 978-3-319-56148-6
eBook Packages: Computer ScienceComputer Science (R0)