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Character-Based Phylogeny Construction and Its Application to Tumor Evolution

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Unveiling Dynamics and Complexity (CiE 2017)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 10307))

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Abstract

Character-based Phylogeny Construction is a well-known combinatorial problem whose input is a matrix M and we want to compute a phylogeny that is compatible with the actual species encoded by M.

In this paper we survey some of the known formulations and algorithms for some variants of this problem. Finally, we present the connections between these problems and tumor evolution, and we discuss some of the most important open problems.

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Acknowledgments

We acknowledge the support of the MIUR PRIN 2010–2011 grant “Automi e Linguaggi Formali: Aspetti Matematici e Applicativi” code 2010LYA9RH, of the Cariplo Foundation grant 2013–0955 (Modulation of anti cancer immune response by regulatory non-coding RNAs), of the FA grants 2013-ATE-0281, 2014-ATE-0382, and 2015-ATE-0113.

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Authors and Affiliations

  1. DISCo, University of Milano–Bicocca, Milan, Italy

    Gianluca Della Vedova, Murray Patterson, Raffaella Rizzi & Mauricio Soto

Authors
  1. Gianluca Della Vedova
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  2. Murray Patterson
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  3. Raffaella Rizzi
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  4. Mauricio Soto
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Corresponding author

Correspondence to Gianluca Della Vedova .

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Editors and Affiliations

  1. University of Turku, Turku, Finland

    Jarkko Kari

  2. Christian-Albrechts-University of Kiel, Kiel, Germany

    Florin Manea

  3. Åbo Akademi University, Turku, Finland

    Ion Petre

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Della Vedova, G., Patterson, M., Rizzi, R., Soto, M. (2017). Character-Based Phylogeny Construction and Its Application to Tumor Evolution. In: Kari, J., Manea, F., Petre, I. (eds) Unveiling Dynamics and Complexity. CiE 2017. Lecture Notes in Computer Science(), vol 10307. Springer, Cham. https://doi.org/10.1007/978-3-319-58741-7_1

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  • DOI: https://doi.org/10.1007/978-3-319-58741-7_1

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  • Print ISBN: 978-3-319-58740-0

  • Online ISBN: 978-3-319-58741-7

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