Abstract
In this paper, we presented the results of data analysis of 1-year measurements from diabetes patients within the Slovenian healthcare project eCare. We focused on looking for groups/clusters of patients with the similar time profile of the glucose values and describe those patients with their clinical status. We treated in a similar way the WONCA scores (i.e., patients’ functional status). Considering the complexity of the data at hand (time series with a different number of measurements and different time intervals), we used predictive clustering trees with dynamic time warping as the distance between time series. The obtained PCTs identified several groups of patients that exhibit similar behavior. More specifically, we described groups of patients that are able to keep under control their disease, and groups that are less successful in that. Furthermore, we identified and described groups of patients that have similar functional status.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Abraham, C., Michie, S.: A taxonomy of behavior change techniques used in interventions. Health Psychol.: Off. J. Div. Health Psychol. Am. Psychol. Assoc. 27(3), 379–387 (2008)
Beštek, M., Brodnik, A.: Interoperability and mHealth precondition for successful eCare. In: Adibi, S. (ed.) Mobile Health (mHeath) The Technology Road Map. Springer Series in Bio-/Neuroinformatics. Springer, Switzerland (2014). doi:10.1007/978-3-319-12817-7_16
Beštek, M., Brodnik, A.: Preconditions for successful eCare. Inform. Med. Slov. 20(1–2), 17–29 (2015)
Blockeel, H.: Top-down induction of first order logical decision trees. Ph.D. thesis, Katholieke Universiteit Leuven, Leuven, Belgium (1998)
Breiman, L., Friedman, J., Olshen, R., Stone, C.J.: Classification and Regression Trees. Chapman & Hall/CRC, Boca Raton (1984)
Debeljak, M., Squire, G.R., Kocev, D., Hawes, C., Young, M.W., Džeroski, S.: Analysis of time series data on agroecosystem vegetation using predictive clustering trees. Ecol. Model. 222(14), 2524–2529 (2011)
Džeroski, S.: Introduction: the challenges for data mining. In: 5th International Workshop Knowledge Discovery in Inductive Databases, KDID 2006, pp. 259–300 (2007)
Eljil, K.A.A.S.: Predicting hypoglycemia. In: Diabetic Patients Using Machine Learning Techniques, pp. 1–92. Faculty of the American University of Sharjah College of Engineering, UAE (2014)
Georga, E., Protopappas, V.C.: Short-term vs. long-term analysis of diabetes data: application of machine learning and data mining techniques. In: IEEE 13th International Conference on Bioinformatics and Bioengineering (BIBE) (2013)
Gjorgjioski, V.: Distance-based learning from structured data. Ph.D. thesis, International postgraduate school Jožef Stefan, Ljubljana, Slovenia (2015)
Karpel’ev, V.A., Filippov, Y., Tarasov, Y., Boyarsky, M.D., Mayorov, A., Shestakova, M.V., Dedov, I.I.: Mathematical modeling of the blood glucose regulation system in diabetes mellitus patients. Vestn. Ross. Akad. Med. Nauk 70(5), 549–560 (2015). https://www.scopus.com/inward/record.uri?eid=2-s2.0-84948981003&doi=10.15690%2Fvramn.v70.i5.1441&partnerID=40&md5=b578cbe1711a9bee957a656eb681c1c2
Kavakiotis, I., Tsave, O., Salifoglou, A., Maglaveras, N., Vlahavas, I., Chouvarda, I.: Machine learning and data mining methods in diabetes research. Comput. Struct. Biotechnol. J. 15, 104–116 (2017). http://dx.doi.org/10.1016/j.csbj.2016.12.005
Kocev, D., Vens, C., Struyf, J., Džeroski, S.: Tree ensembles for predicting structured outputs. Pattern Recognit. 46(3), 817–833 (2013)
Lenert, L., Norman, G.J., Mailhot, M., Patrick, K.: A framework for modeling health behavior protocols and their linkage to behavioral theory. J. Biomed. Inform. 38(4), 270–280 (2005)
Marinov, M., Mosa, A.S.M., Yoo, I., Boren, S.A.: Data-mining technologies for diabetes: a systematic review. J. Diabetes Sci. Technol. 5(6), 1549–1556 (2011). http://dst.sagepub.com/lookup/doi/10.1177/193229681100500631
Reifman, J., Rajaraman, S., Gribok, A., Ward, W.K.: Predictive monitoring for improved management of glucose levels. J. Diabetes Sci. Technol. 1(4), 478–486 (2007). https://www.scopus.com/inward/record.uri?eid=2-s2.0-52449101078&partnerID=40&md5=07e50cc16ed4d23ac38ba713efed205a
Sakoe, H., Chiba, S.: Dynamic programming algorithm optimization for spokenword recognition. IEEE Trans. Acoust. Speech Signal Process. ASSP–26, 43–49 (1978)
Shivakumar, B.L.: A survey on data-mining technologies for prediction and diagnosis of diabetes (2014)
Slavkov, I., Gjorgjioski, V., Struyf, J., Džeroski, S.: Finding explained groups of time-course gene expression profiles with predictive clustering trees. Mol. BioSyst. 6(4), 729–740 (2010)
Sowjanya, K., Singhal, A., Choudhary, C.: MobDBTest: a machine learning based system for predicting diabetes risk using mobile devices. In: 2015 IEEE International Advance Computing Conference (IACC), pp. 397–402 (2015)
Sumalatha, G., Muniraj, N.J.R.: Survey on medical diagnosis using data mining techniques. In: 2013 International Conference on Optical Imaging Sensor and Security (ICOSS), pp. 1–8 (2013). http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6678433
Zecchin, C., Facchinetti, A., Sparacino, G., Cobelli, C.: Reduction of number and duration of hypoglycemic events by glucose prediction methods: a proof-of-concept in silico study. Diabetes Technol. Therapeutics 15(1), 66–77 (2013)
Zhao, C., Yu, C.: Rapid model identification for online subcutaneous glucose concentration prediction for new subjects with type i diabetes. IEEE Trans. Biomed. Eng. 62(5), 1333–1344 (2015). https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929075114&doi=10.1109%2FTBME.2014.2387293&partnerID=40&md5=e23db851493020e4f51367ce89f66dcb
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this paper
Cite this paper
Beštek, M., Kocev, D., Džeroski, S., Brodnik, A., Iljaž, R. (2017). Modelling Time-Series of Glucose Measurements from Diabetes Patients Using Predictive Clustering Trees. In: ten Teije, A., Popow, C., Holmes, J., Sacchi, L. (eds) Artificial Intelligence in Medicine. AIME 2017. Lecture Notes in Computer Science(), vol 10259. Springer, Cham. https://doi.org/10.1007/978-3-319-59758-4_11
Download citation
DOI: https://doi.org/10.1007/978-3-319-59758-4_11
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-59757-7
Online ISBN: 978-3-319-59758-4
eBook Packages: Computer ScienceComputer Science (R0)