Skip to main content

Multi-scale Volumetric ConvNet with Nested Residual Connections for Segmentation of Anterior Cranial Base

  • Conference paper
  • First Online:
Machine Learning in Medical Imaging (MLMI 2017)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 10541))

Included in the following conference series:

Abstract

Anterior cranial base (ACB) is known as the growth-stable structure. Automatic segmentation of the ACB is a prerequisite to superimpose orthodontic inter-treatment cone-beam computed tomography (CBCT) images. The automatic ACB segmentation is still a challenging task because of the ambiguous intensity distributions around fine-grained structures and artifacts due to the limited radiation dose. We propose a fully automatic segmentation of the ACB from CBCT images by a volumetric convolutional network with nested residual connections (NRN). The multi-scale feature fusion in the NRN not only promotes the information flows, but also introduces the supervision to multiple intermediate layers to speed up the convergence. The multi-level shortcut connections augment the feature maps in the decompression pathway and the end-to-end voxel-wise label prediction. The proposed NRN has been applied to the ACB segmentation from clinically-captured CBCT images. The quantitative assessment over the practitioner-annotated ground truths demonstrates the proposed method produces improvements to the state-of-the-arts.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Afrand, M., Ling, C.P., Khosrotehrani, S., Flores-Mir, C., Lagravère-Vich, M.O.: Anterior cranial-base time-related changes: a systematic review. Am. J. Orthod. Dentofac. Orthop. 146(1), 21–32 (2014)

    Article  Google Scholar 

  2. Kayalibay, B., Jensen, G., van der Smagt, P.: Cnn-based segmentation of medical imaging data. arXiv:1701.03056 [cs.CV] (2017)

  3. Brosch, T., Tang, L.Y., Yoo, Y., Li, D.K., Traboulsee, A., Tam, R.: Deep 3d convolutional encoder networks with shortcuts for multiscale feature integration applied to multiple sclerosis lesion segmentation. IEEE TMI 35(5), 1229–1239 (2016)

    Google Scholar 

  4. Cevidanes, L.H., Motta, A., Proffit, W.R., Ackerman, J.L., Styner, M.: Cranial base superimposition for 3-dimensional evaluation of soft-tissue changes. Am. J. Orthod. Dentofac. Orthop. 137(4), S120–S129 (2010)

    Article  Google Scholar 

  5. Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3D U-Net: learning dense volumetric segmentation from sparse annotation. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 424–432. Springer, Cham (2016). doi:10.1007/978-3-319-46723-8_49

    Chapter  Google Scholar 

  6. Coup, P., Tong, T., Misawa, K., Fujiwara, M., Mori, K., Rueckert, D., Glocker, B., Manjn, J.V., Fonov, V., Pruessner, J., Robles, M., Collins, D.L.: Patch-based segmentation using expert priors: application to hippocampus and ventricle segmentation. NeuroImage 54(2), 940–954 (2011)

    Article  Google Scholar 

  7. Hariharan, B., Arbeláez, P., Girshick, R., Malik, J.: Hypercolumns for object segmentation and fine-grained localization. In: CVPR, pp. 447–456 (2015)

    Google Scholar 

  8. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: CVPR, pp. 770–778 (2016)

    Google Scholar 

  9. Li, C., Xu, C., Gui, C., Fox, M.D.: Level set evolution without re-initialization: a new variational formulation. In: CVPR, vol. 1, pp. 430–436 (2005)

    Google Scholar 

  10. Milletari, F., Navab, N., Ahmadi, S.A.: V-net: fully convolutional neural networks for volumetric medical image segmentation. In: 3DV, pp. 565–571

    Google Scholar 

  11. Mostajabi, M., Yadollahpour, P., Shakhnarovich, G.: Feedforward semantic segmentation with zoom-out features. In: CVPR, pp. 3376–3385 (2015)

    Google Scholar 

  12. Noh, H., Hong, S., Han, B.: Learning deconvolution network for semantic segmentation. In: ICCV, pp. 1520–1528 (2015)

    Google Scholar 

  13. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). doi:10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  14. Xie, S., Tu, Z.: Holistically-nested edge detection. In: ICCV, pp. 1395–1403 (2015)

    Google Scholar 

  15. Yu, L., Yang, X., Chen, H., Qin, J., Heng, P.A.: Volumetric convnets with mixed residual connections for automated prostate segmentation from 3d mr images. In: AAAI (2017)

    Google Scholar 

  16. Zhang, S., Zhan, Y., Dewan, M., Huang, J., Metaxas, D.N., Zhou, X.S.: Deformable segmentation via sparse shape representation. In: Fichtinger, G., Martel, A., Peters, T. (eds.) MICCAI 2011. LNCS, vol. 6892, pp. 451–458. Springer, Heidelberg (2011). doi:10.1007/978-3-642-23629-7_55

    Chapter  Google Scholar 

Download references

Acknowledgments

This work was supported by National Natural Science Foundation of China under Grant 61272342.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yuru Pei .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Pei, Y. et al. (2017). Multi-scale Volumetric ConvNet with Nested Residual Connections for Segmentation of Anterior Cranial Base. In: Wang, Q., Shi, Y., Suk, HI., Suzuki, K. (eds) Machine Learning in Medical Imaging. MLMI 2017. Lecture Notes in Computer Science(), vol 10541. Springer, Cham. https://doi.org/10.1007/978-3-319-67389-9_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-67389-9_15

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-67388-2

  • Online ISBN: 978-3-319-67389-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics