Abstract
Intraoperative ultrasound is an imaging modality frequently used to provide delineation of tissue boundaries. This paper proposes a simulation platform that enables rehearsal of patient-specific deformable ultrasound scanning in real-time, using preoperative CT as the data source. The simulation platform was implemented within the GPU-accelerated NVIDIA FleX position-based dynamics framework. The high-resolution particle model is used to deform both surface and volume meshes. The latter is used to compute the barycentric coordinates of each simulated ultrasound image pixel in the surrounding volume, which is then mapped back to the original undeformed CT volume. To validate the computation of simulated ultrasound images, a kidney phantom with an embedded tumour was CT-scanned in the rest position and at five different levels of probe-induced deformation. Measures of normalised cross-correlation and similarity between features were adopted to compare pairs of simulated and ground truth images. The accurate results demonstrate the potential of this approach for clinical translation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Reichl, T., Passenger, J., Acosta, O., Salvado, O.: Ultrasound goes GPU: real-time simulation using CUDA. In: SPIE Medical Imaging, International Society for Optics and Photonics, p. 726116 (2009)
Shams, R., Hartley, R., Navab, N.: Real-time simulation of medical ultrasound from CT images. In: Metaxas, D., Axel, L., Fichtinger, G., Székely, G. (eds.) MICCAI 2008. LNCS, vol. 5242, pp. 734–741. Springer, Heidelberg (2008). doi:10.1007/978-3-540-85990-1_88
Salehi, M., Ahmadi, S.-A., Prevost, R., Navab, N., Wein, W.: Patient-specific 3D ultrasound simulation based on convolutional ray-tracing and appearance optimization. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9350, pp. 510–518. Springer, Cham (2015). doi:10.1007/978-3-319-24571-3_61
Pheiffer, T.S., Thompson, R.C., Rucker, D.C., Simpson, A.L., Miga, M.I.: Model-based correction of tissue compression for tracked ultrasound in soft tissue image-guided surgery. Ultrasound Med. Biol. 40(4), 788–803 (2014)
Flack, B., Makhinya, M., Goksel, O.: Model-based compensation of tissue deformation during data acquisition for interpolative ultrasound simulation. In: 2016 IEEE 13th International Symposium Biomedical Imaging (ISBI), pp. 502–505 (2016)
Goksel, O., Salcudean, S.E.: B-mode ultrasound image simulation in deformable 3-D medium. IEEE Trans. Med. Imaging 28(11), 1657–1669 (2009)
Selmi, S.-Y., Promayon, E., Sarrazin, J., Troccaz, J.: 3D interactive ultrasound image deformation for realistic prostate biopsy simulation. In: Bello, F., Cotin, S. (eds.) ISBMS 2014. LNCS, vol. 8789, pp. 122–130. Springer, Cham (2014). doi:10.1007/978-3-319-12057-7_14
Bürger, B., Bettinghausen, S., Radle, M., Hesser, J.: Real-time GPU-based ultrasound simulation using deformable mesh models. IEEE Trans. Med. Imaging 32(3), 609–618 (2013)
Morin, R., Eiben, B., Bidaut, L., Hipwell, J., Evans, A., Hawkes, D.J.: 3D ultrasound simulation based on a biomechanical model of prone MRI in breast cancer imaging. In: 2015 IEEE 12th International Symposium Biomedical Imaging (ISBI), pp. 264–267 (2015)
Camara, M., Mayer, E., Darzi, A., Pratt, P.: Soft tissue deformation for surgical simulation: a position-based dynamics approach. Int. J. Comput. Assist. Radiol. Surg. 11(6), 919–928 (2016)
Hughes-Hallett A.: The image-enhanced operating environment in robot assisted laparoscopic partial nephrectomy. Imperial College London (2016)
NVIDIA Gameworks. Nvidia FleX. https://developer.nvidia.com/flex
Kavan, L.: Part I: direct skinning methods and deformation primitives. In: ACM SIGGRAPH, pp. 1–11 (2014)
Miller, K., Lu, J.: On the prospect of patient-specific biomechanics without patient-specific properties of tissues. J. Mech. Behav. Biomed. Mater. 27, 154–166 (2013)
Rodero, C., Real, P., Zuñeda, P., Monteagudo, C., Lozano, M., GarcÃa-Fernández, I.: Characterisation of position based dynamics for elastic materials. In: Proceedings of the XXVI Spanish Computer Graphics Conference, pp. 49–57 (2016)
Acknowledgements
The authors are grateful for the support from the Northwick Park Institute for Medical Research, the Hamlyn Centre for Robotic Surgery and from The Imperial NIHR Biomedical Research Centre (BRC).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this paper
Cite this paper
Camara, M., Mayer, E., Darzi, A., Pratt, P. (2017). Simulation of Patient-Specific Deformable Ultrasound Imaging in Real Time. In: Cardoso, M., et al. Imaging for Patient-Customized Simulations and Systems for Point-of-Care Ultrasound. BIVPCS POCUS 2017 2017. Lecture Notes in Computer Science(), vol 10549. Springer, Cham. https://doi.org/10.1007/978-3-319-67552-7_2
Download citation
DOI: https://doi.org/10.1007/978-3-319-67552-7_2
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-67551-0
Online ISBN: 978-3-319-67552-7
eBook Packages: Computer ScienceComputer Science (R0)