Abstract
Calcium signalling is a good bio-inspired method for molecular communication due to the advantages of biocompatibility, stability, and long communication range. In this paper, we investigate a few channel characteristics of calcium signaling transfer systems including propagation distance and time delay based on a novel inter-cellular calcium wave (ICW) propagation model. Our model is the first one that can investigate the impact of some exclusive parameters in ICW (e.g., the gap junction permeability). Understanding the channel transfer characteristics of ICW can provide a significant reference for the calcium signaling application in molecular communication. In the future, theoretical and simulation results in this paper can help in the design of molecular communication systems between nanodevices.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Akyildiz, I.F., Brunetti, F., Blazquez, C.: Nanonetworks: a new communication paradigm. Comput. Netw. 52(12), 2260–2279 (2008)
Akyildiz, I.F.: Nanonetworks: a new frontier in communications. In: Proceedings of the 2010, SECRYPT, Athens, Greece, p. IS-5 (2010)
Atakan, B., Akan, O.B., Balasubramaniam, S.: Body area nanonetworks with molecular communications in nanomedicine. IEEE Commun. Mag. 50(1), 28–34 (2012)
Nakano, T.: Biologically inspired network systems: a review and future prospects. IEEE Trans. Syst. Man Cybern. C 41(5), 630–643 (2011)
Kuran, M.S., Tugcu, T., Edis, B.O.: Calcium signaling: overview and research directions of a molecular communication paradigm. IEEE Wirel. Commun. 19(5), 20–27 (2012)
Barros, M.T.: Ca\(^{2+}\)-signaling-based molecular communication systems: design and future research directions. Nano Commun. Netw. 11, 103–113 (2017)
Barros, M.T., Balasubramaniam, S., Jennings, B.: Comparative end-to-end analysis of Ca\(^{2+}\) signaling-based molecular communication in biological tissues. IEEE Trans. Commun. 63, 5128–5142 (2015)
Fink, C., Slepchenko, B., Moraru, I.: An image-based model of calcium waves in differentiated neuroblastoma cells. Biophys. J. 79(1), 163–169 (2000)
Sobie, E., Dilly, K., Dos, S.: Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release. Biophys. J. 83(1), 59–63 (2005)
Bicen, A.O., Akyildiz, I.F., Balasubramaniam, S., Koucheryavy, Y.: Linear channel modeling and error analysis for intra/inter-cellular calcium molecular communication. IEEE Trans. NanoBiosci. 15(5), 488–498 (2016)
Nakano, T., Liu, J.Q.: Design and analysis of molecular relay channels: an information theoretic approach. IEEE Trans. NanoBiosci. 9(3), 213–221 (2010)
Kilinc, D., Akan, O.B.: An information theoretical analysis of nanoscale molecular gap junction communication channel between cardiomyocytes. IEEE Trans. Nanotechnol. 12(2), 129–136 (2013)
Nakano, T., Suda, T., Koujin, T., Haraguchi, T., Hiraoka, Y.: Molecular communication through gap junction channels. In: Priami, C., Dressler, F., Akan, O.B., Ngom, A. (eds.) Transactions on Computational Systems Biology X. LNCS, vol. 5410, pp. 81–99. Springer, Heidelberg (2008). https://doi.org/10.1007/978-3-540-92273-5_5
Houart, G., Dupont, G., Goldbeter, A.: Bursting, chaos and birhythmicity originating from self-modulation of the inositol 1, 4, 5-trisphosphate signal in a model for intracellular Ca(2+) oscillations. Bull. Math. Biol. 61(3), 507–530 (1999)
Acknowledgment
The authors gratefully acknowledge the support from the EPSRC TOUCAN project (Grant No. EP/L020009/1), the EU FP7 QUICK project (Grant No. PIRSES-GA-2013-612652), the EU H2020 5G Wireless project (Grant NO. 641985), Natural Science Foundation of China (Grant No. 61210002 and 61371110), and Key R&D Program of Shandong Province (Grant No. 2016GGX101014).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering
About this paper
Cite this paper
Chang, H., Bian, J., Sun, J., Zhang, W., Wang, CX. (2018). A Novel Channel Model for Molecular Communications Based on Inter-cellular Calcium Wave. In: Li, C., Mao, S. (eds) Wireless Internet. WiCON 2017. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, vol 230. Springer, Cham. https://doi.org/10.1007/978-3-319-90802-1_25
Download citation
DOI: https://doi.org/10.1007/978-3-319-90802-1_25
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-90801-4
Online ISBN: 978-3-319-90802-1
eBook Packages: Computer ScienceComputer Science (R0)