Skip to main content

Remifentanil Dose Prediction for Patients During General Anesthesia

  • Conference paper
  • First Online:
Hybrid Artificial Intelligent Systems (HAIS 2018)

Abstract

In the anesthesia field there are some challenges, such as achieving new methods to control, and, of course, for reducing the pain suffered for the patients during surgeries. The first steps in this field were focused on obtaining representative measurements for pain measurement. Nowadays, one of the most promiser index is the ANI (Antinociception Index). This research works deals the model for the remifentanil dose prediction for patients undergoing general anesthesia. To do that, a hybrid model based on intelligent techniques is implemented. The model was trained using Support Vector Regression (SVR) and Artificial Neural Networks (ANN) algorithms. Results were validated with a real dataset of patients. It was possible to check the really successful model performance.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Chang, J.J., Syafiie, S., Kamil, R., Lim, T.A.: Automation of anaesthesia: a review on multivariable control. J. Clin. Monit. Comput. 29(2), 231–239 (2015)

    Article  Google Scholar 

  2. Mendez, J.A., Marrero, A., Reboso, J.A., Leon, A.: Adaptive fuzzy predictive controller for anesthesia delivery. Control Eng. Pract. 46, 1–9 (2016)

    Article  Google Scholar 

  3. Marrero, A., Méndez, J.A., Reboso, J.A., Martín, I., Calvo, J.L.: Adaptive fuzzy modeling of the hypnotic process in anesthesia. J. Clin. Monit. Comput. 31(2), 319–330 (2017)

    Article  Google Scholar 

  4. Casteleiro-Roca, J., Calvo-Rolle, J., Meizoso-Lopez, M., Piñon-Pazos, A., Rodriguez-Gómez, B.: New approach for the QCM sensors characterization. Sens. Actuators, A 207, 1–9 (2014)

    Article  Google Scholar 

  5. Crespo-Ramos, M.J., Machón-González, I., López-García, H., Calvo-Rolle, J.L.: Detection of locally relevant variables using SOM-NG algorithm. Eng. Appl. Artif. Intell. 26(8), 1992–2000 (2013)

    Article  Google Scholar 

  6. Cowen, R., Stasiowska, M.K., Laycock, H., Bantel, C.: Assessing pain objectively: the use of physiological markers. Anaesthesia 70(7), 828–847 (2015)

    Article  Google Scholar 

  7. Ledowski, T.: Analgesia-nociception index. Br. J. Anaesth. 112(5), 937 (2014)

    Article  Google Scholar 

  8. Jeanne, M., Clément, C., De Jonckheere, J., Logier, R., Tavernier, B.: Variations of the analgesia nociception index during general anaesthesia for laparoscopic abdominal surgery. J. Clin. Monit. Comput. 26(4), 289–294 (2012)

    Article  Google Scholar 

  9. Jove, E., Gonzalez-Cava, J.M., Casteleiro-Roca, J.L., Pérez, J.A.M., Calvo-Rolle, J.L., de Cos Juez, F.J.: An intelligent model to predict ANI in patients undergoing general anesthesia. In: Pérez García, H., Alfonso-Cendón, J., Sánchez González, L., Quintián, H., Corchado, E. (eds.) SOCO/CISIS/ICEUTE -2017. AISC, vol. 649, pp. 492–501. Springer, Cham (2018). https://doi.org/10.1007/978-3-319-67180-2_48

    Chapter  Google Scholar 

  10. Casteleiro-Roca, J.L., Pérez, J.A.M., Piñón-Pazos, A.J., Calvo-Rolle, J.L., Corchado, E.: Modeling the electromyogram (EMG) of patients undergoing anesthesia during surgery. In: Herrero, Á., Sedano, J., Baruque, B., Quintián, H., Corchado, E. (eds.) 10th International Conference on Soft Computing Models in Industrial and Environmental Applications. AISC, vol. 368, pp. 273–283. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-19719-7_24

    Chapter  Google Scholar 

  11. Gonzalez-Cava, J.M., Reboso, J.A., Casteleiro-Roca, J.L., Calvo-Rolle, J.L., Méndez Pérez, J.A.: A novel fuzzy algorithm to introduce new variables in the drug supply decision-making process in medicine. In: Complexity 2018 (2018)

    Article  Google Scholar 

  12. Ghanghermeh, A., Roshan, G., Orosa, J.A., Calvo-Rolle, J.L., Costa, A.M.: New climatic indicators for improving urban sprawl: a case study of Tehran city. Entropy 15(3), 999–1013 (2013)

    Article  Google Scholar 

  13. Calvo-Rolle, J.L., Quintian-Pardo, H., Corchado, E., del Carmen Meizoso-López, M., García, R.F.: Simplified method based on an intelligent model to obtain the extinction angle of the current for a single-phase half wave controlled rectifier with resistive and inductive load. J. Appl. Logic 13(1), 37–47 (2015)

    Article  Google Scholar 

  14. Calvo-Rolle, J.L., Fontenla-Romero, O., Pérez-Sánchez, B., Guijarro-Berdinas, B.: Adaptive inverse control using an online learning algorithm for neural networks. Informatica 25(3), 401–414 (2014)

    Article  Google Scholar 

  15. Casteleiro-Roca, J.L., Calvo-Rolle, J.L., Meizoso-López, M.C., Piñón-Pazos, A., Rodríguez-Gómez, B.A.: Bio-inspired model of ground temperature behavior on the horizontal geothermal exchanger of an installation based on a heat pump. Neurocomputing 150, 90–98 (2015)

    Article  Google Scholar 

  16. Machón-González, I., López-García, H., Calvo-Rolle, J.L.: A hybrid batch SOM-NG algorithm. In: The 2010 International Joint Conference on Neural Networks (IJCNN), pp. 1–5. IEEE (2010)

    Google Scholar 

  17. Alaiz Moretón, H., Calvo Rolle, J., García, I., Alonso Alvarez, A.: Formalization and practical implementation of a conceptual model for PID controller tuning. Asian J. Control 13(6), 773–784 (2011)

    Article  Google Scholar 

  18. Rolle, J., Gonzalez, I., Garcia, H.: Neuro-robust controller for non-linear systems. DYNA 86(3), 308–317 (2011)

    Article  Google Scholar 

  19. Jove, E., Aláiz-Moretón, H., Casteleiro-Roca, J.L., Corchado, E., Calvo-Rolle, J.L.: Modeling of bicomponent mixing system used in the manufacture of wind generator blades. In: Corchado, E., Lozano, J.A., Quintián, H., Yin, H. (eds.) IDEAL 2014. LNCS, vol. 8669, pp. 275–285. Springer, Cham (2014). https://doi.org/10.1007/978-3-319-10840-7_34

    Chapter  Google Scholar 

  20. Casteleiro-Roca, J.L., Jove, E., Sánchez-Lasheras, F., Méndez-Pérez, J.A., Calvo-Rolle, J.L., de Cos Juez, F.J.: Power cell SOC modelling for intelligent virtual sensor implementation. J. Sens. 2017, 10 (2017)

    Article  Google Scholar 

  21. Casteleiro-Roca, J.L., Calvo-Rolle, J.L., Méndez Pérez, J.A., Roqueñí Gutiérrez, N., de Cos Juez, F.J.: Hybrid intelligent system to perform fault detection on BIS sensor during surgeries. Sensors 17(1), 179 (2017)

    Article  Google Scholar 

  22. Gonzalez-Cava, J.M., et al.: A machine learning based system for analgesic drug delivery. In: Pérez García, H., Alfonso-Cendón, J., Sánchez González, L., Quintián, H., Corchado, E. (eds.) SOCO/CISIS/ICEUTE -2017. AISC, vol. 649, pp. 461–470. Springer, Cham (2018). https://doi.org/10.1007/978-3-319-67180-2_45

    Chapter  Google Scholar 

  23. García, R.F., Rolle, J.L.C., Gomez, M.R., Catoira, A.D.: Expert condition monitoring on hydrostatic self-levitating bearings. Expert Syst. Appl. 40(8), 2975–2984 (2013)

    Article  Google Scholar 

  24. Calvo-Rolle, J.L., Casteleiro-Roca, J.L., Quintián, H., del Carmen Meizoso-Lopez, M.: A hybrid intelligent system for PID controller using in a steel rolling process. Expert Syst. Appl. 40(13), 5188–5196 (2013)

    Article  Google Scholar 

  25. García, R.F., Rolle, J.L.C., Castelo, J.P., Gomez, M.R.: On the monitoring task of solar thermal fluid transfer systems using NN based models and rule based techniques. Eng. Appl. Artif. Intell. 27, 129–136 (2014)

    Article  Google Scholar 

  26. Quintián, H., Calvo-Rolle, J.L., Corchado, E.: A hybrid regression system based on local models for solar energy prediction. Informatica 25(2), 265–282 (2014)

    Article  Google Scholar 

  27. Quintian Pardo, H., Calvo Rolle, J.L., Fontenla Romero, O.: Application of a low cost commercial robot in tasks of tracking of objects. DYNA 79(175), 24–33 (2012)

    Google Scholar 

  28. Wasserman, P.: Advanced Methods in Neural Computing, 1st edn. Wiley, New York (1993)

    MATH  Google Scholar 

  29. Zeng, Z., Wang, J.: Advances in Neural Network Research and Applications, 1st edn. Springer, Heidelberg (2010). https://doi.org/10.1007/978-3-642-12990-2

    Book  Google Scholar 

  30. Vapnik, V.: The Nature of Statistical Learning Theory. Springer, New York (1995). https://doi.org/10.1007/978-1-4757-3264-1

    Book  MATH  Google Scholar 

  31. Kaski, S., Sinkkonen, J., Klami, A.: Discriminative clustering. Neurocomputing 69(1–3), 18–41 (2005)

    Article  Google Scholar 

  32. Fernández-Serantes, L.A., Estrada Vázquez, R., Casteleiro-Roca, J.L., Calvo-Rolle, J.L., Corchado, E.: Hybrid intelligent model to predict the SOC of a LFP power cell type. In: Polycarpou, M., de Carvalho, A.C.P.L.F., Pan, J.-S., Woźniak, M., Quintian, H., Corchado, E. (eds.) HAIS 2014. LNCS (LNAI), vol. 8480, pp. 561–572. Springer, Cham (2014). https://doi.org/10.1007/978-3-319-07617-1_49

    Chapter  Google Scholar 

  33. Li, Y., Shao, X., Cai, W.: A consensus least squares support vector regression (LS-SVR) for analysis of near-infrared spectra of plant samples. Talanta 72(1), 217–222 (2007)

    Article  Google Scholar 

  34. Casteleiro-Roca, J.L., Quintián, H., Calvo-Rolle, J.L., Corchado, E., del Carmen Meizoso-López, M., Piñón-Pazos, A.: An intelligent fault detection system for a heat pump installation based on a geothermal heat exchanger. J. Appl. Logic 17, 36–47 (2016)

    Article  MathSciNet  Google Scholar 

Download references

Acknowledgments

Jose M. Gonzalez-Cava’s research was supported by the Spanish Ministry of Education, Culture and Sport (www.mecd.gob.es), under the “Formación de Profesorado” grant FPU15/03347.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Esteban Jove .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Jove, E. et al. (2018). Remifentanil Dose Prediction for Patients During General Anesthesia. In: de Cos Juez, F., et al. Hybrid Artificial Intelligent Systems. HAIS 2018. Lecture Notes in Computer Science(), vol 10870. Springer, Cham. https://doi.org/10.1007/978-3-319-92639-1_45

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-92639-1_45

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-92638-4

  • Online ISBN: 978-3-319-92639-1

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics