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3D Spatial Analysis of fMRI Data on a Word Perception Task

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Independent Component Analysis and Blind Signal Separation (ICA 2004)

Abstract

We discuss a 3D spatial analysis of fMRI data taken during a combined word perception and motor task. The event – based experiment was part of a study to investigate the network of neurons involved in the perception of speech and the decoding of auditory speech stimuli. We show that a classical general linear model analysis using SPM does not yield reasonable results. With blind source separation (BSS) techniques using the FastICA algorithm it is possible to identify different independent components (IC) in the auditory cortex corresponding to four different stimuli. Most interesting, we could detect an IC representing a network of simultaneously active areas in the inferior frontal gyrus responsible for word perception.

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References

  1. Kwong, K.K., Belliveau, J.W., Chester, D.A., Goldberg, I.E., Weisskoff, R.M., Poncelet, B.P., Kennedy, D.N., Hoppel, B.E., Cohen, M.S., Turner, R., Cheng, H.-M., Brady, T.J., Rosen, B.R.: Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. USA 89, 5675–5679 (1992)

    Article  Google Scholar 

  2. Ogawa, S., Lee, T.M., Kay, A.R., Tank, D.W.: Brain magnetic-resonance-imaging with contrast dependent on blood oxygenation. Proc. Natl Acad. Sci. USA 87, 9868–9872 (1990)

    Article  Google Scholar 

  3. Frackowiak, R.S.J., Friston, K.J., Frith, C.D., Dolan, R.J., Mazziotta, J.C.: Human Brain Function. Academic Press, San Diego (1997)

    Google Scholar 

  4. Bell, A.J., Sejnowski, T.J.: An information-maximisation approach to blind separation and blind deconvolution. Neural Computation 7(6), 1129–1159 (1995)

    Article  Google Scholar 

  5. McKeown, M.J., Sejnowski, T.J.: Independent Component Analysis of FMRI Data: Examining the Assumptions. Human Brain Mapping 6, 368–372 (1998)

    Article  Google Scholar 

  6. Hyvärinnen, A.: Fast and Robust Fixed-Point Algorithms for Independent Component Analysis. IEEE Transactions on Neural Networks 10(3), 626–634 (1999)

    Article  Google Scholar 

  7. Esposito, F., Formisano, E., Seifritz, E., Goebel, R., Morrone, R., Tedeschi, G., Di Salle, F.: Spatial Independent Component Analysis of Functional MRI Time-Series: To What Extent Do Results Depend on the Algorithm Used? Human Brain Mapping 16, 146–157 (2002)

    Article  Google Scholar 

  8. Specht, K., Reul, J.: Function segregation of the temporal lobes into highly differentiated subsystems for auditory perception: an auditory rapid event-related fMRI-task. NeuroImage 20, 1944–1954 (2003)

    Article  Google Scholar 

  9. SPM2 (July 2003), http://www.fil.ion.ulc.ac.uk/spm/spm2.html

  10. Calhoun, V.D., Adali, T., Pearlson, G.D., Pekar, J.J.: A Method for Making Group Inferences from Functional MRI Data Using Independent Component Analysis. Human Brain Mapping 14, 140–151 (2001)

    Article  Google Scholar 

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© 2004 Springer-Verlag Berlin Heidelberg

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Keck, I.R., Theis, F.J., Gruber, P., Lang, E.W., Specht, K., Puntonet, C.G. (2004). 3D Spatial Analysis of fMRI Data on a Word Perception Task. In: Puntonet, C.G., Prieto, A. (eds) Independent Component Analysis and Blind Signal Separation. ICA 2004. Lecture Notes in Computer Science, vol 3195. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-30110-3_123

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  • DOI: https://doi.org/10.1007/978-3-540-30110-3_123

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23056-4

  • Online ISBN: 978-3-540-30110-3

  • eBook Packages: Springer Book Archive

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